2 results match your criteria: "Center for Drug Evaluation of China[Affiliation]"
Exp Ther Med
January 2017
Center for Drug Evaluation of China, Beijing 100038, P.R. China.
Yao Xue Xue Bao
December 2003
Center for Drug Evaluation of China, Beijing 100038, China.
Aim: To synthesize acylated prodrug of tacrine hydrochloride (THA) to improve the infiltration ability across the blood brain barrier (BBB).
Methods: A series of prodrugs were prepared by acylation of the 7-amino group of THA. The degradation of prodrugs was investigated under different conditions.