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Hematopoietic Stem Cells in Neural-crest Derived Bone Marrow.
Sci Rep
December 2016
Columbia University Medical Center, Center for Craniofacial Regeneration (CCR) 630 W. 168 St., New York, NY 10032, USA.
Hematopoietic stem cells (HSCs) in the endosteum of mesoderm-derived appendicular bones have been extensively studied. Neural crest-derived bones differ from appendicular bones in developmental origin, mode of bone formation and pathological bone resorption. Whether neural crest-derived bones harbor HSCs is elusive.
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