117 results match your criteria: "Center for Clinical Management Research (CCMR)[Affiliation]"

Enhancing representation of special populations: An approach to the inclusion of women veterans in VA clinical trials.

Contemp Clin Trials

January 2025

VA HSR Center for Innovation to Implementation (Ci2i), VA Palo Alto Health Care System, Palo Alto, CA, USA; Division of Primary Care and Population Health, Stanford University School of Medicine, Stanford, CA, USA.

The under-recruitment of historically marginalized populations into clinical trials thwarts equitable inclusion of individuals who could benefit from healthcare innovations and limits the generalizability of results. For decades, the Veterans Health Administration (VA) has conducted large clinical trials that impact clinical guidelines for veterans and civilians alike. Within the VA, women are a numeric minority, and recruitment of this population into trials is challenged by gender-specific care structures, distinct demographic characteristics, and mistreatment such as higher rates of military sexual trauma and harassment on VA grounds.

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Primary Care Practice Telehealth Use and Low-Value Care Services.

JAMA Netw Open

November 2024

Institute for Healthcare Policy and Innovation, Department of Urology, University of Michigan, Ann Arbor.

Importance: The rapid expansion of telehealth transformed how primary care practices deliver care; however, uncertainties about the quality of telehealth-delivered care compared with in-person care remain. While there are concerns that increased telehealth may introduce wasteful care, how telehealth affects the delivery of low-value care is unknown.

Objective: To examine whether a primary care practice's level of telehealth use is associated with changes in the rates of low-value care.

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Opioid-related emergency admissions in people with opioid dependence/use disorder with and without sickle cell disease: An analysis of multi-state insurance claims.

Gen Hosp Psychiatry

December 2024

Health and Behavior Research Center, Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid Ave, St. Louis, MO 63110, United States of America. Electronic address:

Article Synopsis
  • The study aimed to evaluate opioid-related hospital admissions among patients with sickle cell disease (SCD) who have opioid-related disorders, analyzing a decade's worth of data from over 191,000 individuals in the U.S.
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  • Findings revealed that while patients with SCD had more all-cause admissions, only a small percentage were for opioid-related events, highlighting that vaso-occlusive crises (VOCs) were far more prevalent.
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  • Although SCD patients showed a higher likelihood of opioid-related admissions compared to those without SCD, these events were still relatively uncommon, suggesting that the perception of elevated substance use risk may be overstated.
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Objective: The increasing prevalence of and inequities in childhood obesity demand improved access to effective treatment. The SmartMoves curriculum used in Bright Bodies, a proven-effective, intensive health behavior and lifestyle treatment (IHBLT), was disseminated to ≥30 US sites from 2003 to 2018. We aimed to identify barriers to and facilitators of IHBLT implementation/sustainment.

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Comparison of Treatment Receipt and Hospitalization Among Patients With Stimulant Use Disorder and/or Opioid Use Disorder in the Veterans Health Administration.

J Addict Med

October 2024

From the Department of Health Systems and Population Health, University of Washington School of Public Health, Seattle, WA (MCF); Health Systems Research (HSR) Center of Innovation for Veteran-Centered and Value-Driven Care, VA Puget Sound Health Care System, Seattle, WA (MCF); Michigan Innovations in Addiction Care through Research & Education (MI-ACRE), Addiction Center, Department of Psychiatry, University of Michigan, Ann Arbor, MI (LNC, LZ, LAL); and VA Center for Clinical Management Research (CCMR), VA Ann Arbor Healthcare System, Ann Arbor, MI 48105 (LZ, LAL).

Article Synopsis
  • - The study analyzes service utilization differences between patients with stimulant use disorder (StUD) and those with opioid use disorder (OUD), noting that patients with StUD are often overlooked in comparison to the opioid crisis.
  • - Data from 132,273 veterans reveals that individuals with StUD alone are significantly less likely to receive outpatient treatment compared to those with either OUD alone or co-occurring OUD and StUD, but they have higher chances of being hospitalized and receiving residential treatment.
  • - The findings suggest that patients with StUD may require more focused efforts to improve treatment access and reduce hospitalizations, highlighting a gap in current healthcare responses to stimulant use issues.
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Background: Medications for opioid use disorders (MOUDs) are effective, but most people with opioid use disorder (OUD) do not receive treatment. Prior research has explored patients' structural barriers to access and perceptions of MOUD. Little research has considered treatment knowledge and perceptions outside of the patient population.

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Introduction: In ensuring the timely delivery of emergency care to Veterans, Veterans Affairs (VA) offers both emergency care services in its own facilities and, increasingly, purchases care for Veterans in non-VA (community) emergency department (ED) settings. Although in recent years emergency care coverage has become the single largest contributor to VA community care spending, no study to date has examined Veteran decision-making as it relates to ED setting choice. The purpose of this study is to identify and describe reasons why Veterans choose VA versus non-VA emergency care settings.

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Purpose: Negative perceptions around medications for opioid use disorder (MOUD) amongst the public could deter patients with opioid use disorder (OUD) from engaging with MOUD. Thus, we evaluated whether a brief intervention could improve preferences for MOUD in people who may or may not use opioids.

Methods: We employed a pre-post design to assess the effect of a brief educational intervention on preferences for methadone, buprenorphine, naltrexone, and non-medication treatment in an online sample of US adults stratified by race, who may or may not use opioids.

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Contingency management for substance use disorders in the U.S. Veterans Health Administration: 2018-2022.

J Subst Use Addict Treat

August 2024

Addiction Center, Department of Psychiatry, University of Michigan, Ann Arbor, MI, United States of America; VA Center for Clinical Management Research (CCMR), VA Ann Arbor Healthcare System, Ann Arbor, MI, United States of America.

Article Synopsis
  • Contingency management (CM) is an effective treatment for substance use disorders, notably within the Veterans Health Administration, which implemented a large-scale CM program from 2018 to 2022.
  • A study involving 2,844 patients revealed that the majority were median-aged 52, with many facing homelessness or multiple substance use disorders, and that stimulant use was the focus of 86% of CM visits.
  • While CM was widely adopted, the COVID-19 pandemic led to an 83% drop in CM visits, and the volume of these visits has not yet recovered to levels observed before the pandemic.
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Article Synopsis
  • - The Veterans Health Administration (VHA) implemented 57 evidence-informed practices across 82 facilities through its Diffusion of Excellence program from 2016 to 2021, aiming to understand how these practices transition to long-term sustainment.
  • - A mixed-methods evaluation revealed that after five years, about one-third of facilities fully sustained their practices, while another one-third experienced mixed results or discontinued, leading to a significant variation in primary outcomes.
  • - Facilities that successfully sustained their practices reported overcoming challenges and demonstrated resilience, with 70% showing inconsistent outcomes over time compared to 30% with stable results.
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Perceptions around medications for opioid use disorder among a diverse sample of U.S. adults.

J Subst Use Addict Treat

August 2024

Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; VA Center for Clinical Management Research (CCMR), VA Ann Arbor Healthcare System, Ann Arbor, MI, USA. Electronic address:

Introduction: Medications for opioid use disorder (MOUD) including methadone (MMT), buprenorphine (BUP), and naltrexone (NTX) are safe and effective. However, there are significant negative perceptions surrounding MOUD, creating barriers to uptake. While research on MOUD stigma has largely focused on provider and patient experiences, fewer studies have explored MOUD perceptions among the general public.

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Medical-surgical patients with untreated hazardous drinking: Randomized controlled trial of the DO-MoST intervention to improve health outcomes over 12-month follow-up.

Drug Alcohol Depend

May 2024

Center for Clinical Management Research (CCMR), VA Ann Arbor Healthcare System, 2800 Plymouth Road, Building 16, Ann Arbor, MI 48109, USA; Department of Psychiatry, University of Michigan School of Medicine, 4250 Plymouth Road, Ann Arbor, MI 48109, USA. Electronic address:

Introduction: High prevalence and harmful consequences of hazardous drinking among medical-surgical patients underscore the importance of intervening with drinking to improve patients' health. This study evaluated a novel intervention, "Drinking Options - Motivate, Shared Decisions, Telemonitor" (DO-MoST).

Methods: In a randomized design, 155 medical-surgical patients with untreated hazardous drinking were assigned to enhanced usual care or DO-MoST, and followed 3, 6, and 12 months later.

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Toward a Harm Reduction Approach to Cannabis Use Disorder.

Am J Psychiatry

February 2024

Department of Psychiatry, University of Michigan, Ann Arbor, Mich. (Lin, Bonar, Coughlin); VA Center for Clinical Management Research (CCMR), VA Ann Arbor Healthcare System, Ann Arbor, Mich. (Lin).

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Telehealth-delivered Psychotherapy for the Treatment of Alcohol Use Disorder: Patient Perspectives in the Age of COVID-19.

J Addict Med

November 2023

From the University of Rhode Island, Department of Psychology, Kingston, RI (RG); VA Center for Clinical Management Research (CCMR), VA Ann Arbor Healthcare System, Ann Arbor, MI (JF, LAL); Heinz College of Information Systems and Public Policy, Carnegie Mellon University, Pittsburgh, PA (EP); Addiction Center, Department of Psychiatry, University of Michigan, Ann Arbor, MI (EEB, AF, LAL); and Injury Prevention Center, University of Michigan, Ann Arbor, MI (EEB).

Objectives: The COVID-19 pandemic precipitated increases in alcohol use and ushered in virtually delivered health care, creating an opportunity to examine the impacts of telehealth on alcohol use disorder (AUD) treatment. To understand these impacts, we explored perspectives on telehealth-delivered psychotherapy among individuals with AUD.

Methods: This was a qualitative study using semi-structured interviews.

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Objectives: With support from others, individuals with depression can build skills and implement lifestyle changes that help them manage their illness. The objective of the current study was to understand how the CarePartners for Depression Program, a randomized clinical trial aimed at enhancing the role of caregivers in the management of depression, improved communication and shared understandings of depression among individuals with depression and their close others.

Methods: We conducted in-depth, semi-structured interviews with individuals with depression and their caregivers who participated in the CarePartners program.

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Impact of COVID-19 on stimulant use disorder treatment: A national cohort study in the Veterans Health Administration.

Drug Alcohol Depend

November 2023

Addiction Center, Department of Psychiatry, University of Michigan, Ann Arbor, MI,  USA; VA Center for Clinical Management Research (CCMR), VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.

Objective: Rates of stimulant overdose have increased dramatically, which may have been exacerbated by treatment disruptions during the pandemic, but no recent studies have examined use of stimulant use disorder (StUD) treatment.

Methods: In this retrospective cohort study (March 2018 to February 2022) of national Veterans Health Administration patients, we use an interrupted time-series analysis to examine the impact of COVID-19 (starting in March 2020) on treatment use for StUD.

Results: The number of patients receiving StUD care was increasing pre-COVID (22,640-23,020, February 2018-February 2020) but dropped post-pandemic to 18,578 in February 2022.

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Perceived risk of harm for different methods of cannabis consumption: A brief report.

Drug Alcohol Depend

October 2023

Addiction Center, Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA; Injury Prevention Center, University of Michigan, Ann Arbor, MI, USA.

Background: Emerging adults' (EAs; ages 18-25) perceived risk of cannabis-related harms has decreased in recent decades, potentially contributing to their high prevalence of cannabis consumption. With the changing cannabis policy and product landscape, it is critical to understand perceived risk related to different consumption methods (e.g.

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Telephone monitoring and 15-month outcomes for patients with co-occurring substance use and mental health disorders: Moderating effects of high-risk patient characteristics.

J Subst Use Addict Treat

September 2023

Center for Innovation to Implementation, Veterans Affairs (VA) Health Care System, 795 Willow Rd, Menlo Park, CA 94025, USA; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94304, USA. Electronic address:

Introduction: Telephone monitoring interventions for substance use disorders are an important component of continuing care to reduce relapse and connect patients to services. However, a knowledge gap still exists as to which patient groups benefit most from them. This secondary analysis of a randomized controlled trial examined moderators of associations between telephone monitoring and 15-month substance use outcomes among patients with co-occurring substance use and mental health disorders.

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