359 results match your criteria: "Center for Biological and Health Sciences[Affiliation]"

Letter to the editor "Quality of life of caregivers of patients on home enteral nutrition".

Clin Nutr

December 2024

Postgraduate Program in Movement Sciences, Center for Biological and Health Sciences, Federal University of Sergipe, São Cristovão 49107-230, Sergipe, Brazil. Electronic address:

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Genetic diversity of Bartonella spp. in vampire bats and associated Streblidae bat flies in the Brazilian Amazon.

Parasitol Int

December 2024

Vector-Borne Bioagents Laboratory (VBBL), Department of Pathology, Reproduction and One Health, School of Agricultural and Veterinarian Sciences, São Paulo State University (Unesp), Jaboticabal, SP, Brazil. Electronic address:

Among mammals, bats stand out as important reservoirs for Bartonella spp., second only to rodents. In Brazil, out of the 182 species of bats described, three are hematophagous: Desmodus rotundus, Diphylla ecaudata and Diaemus youngii.

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The intensive use of oil and its derivatives is related to a greater frequency of accidents involving the release of pollutants that cause harmful effects on ecosystems. Actinobacteria are cosmopolitan and saprophytic microorganisms of great commercial interest, but because they are predominantly found in soil, most research into the products of this phylum's metabolism has focused on this habitat. Marine actinobacteria exhibit unique metabolic characteristics in response to extreme conditions in their habitat, which distinguishes them from terrestrial actinobacteria.

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Article Synopsis
  • - Leprosy, a chronic infectious disease with significant disabling effects, presents a major public health challenge in Brazil, which has the second-highest number of cases globally, following India.
  • - A systematic review and meta-analysis of studies from the last 20 years was conducted to analyze the prevalence of paucibacillary leprosy in Brazil, utilizing various databases and following strict methodological guidelines.
  • - The findings from 48 studies indicated a prevalence rate of 50.5% for paucibacillary cases in Brazil, with regional variations, showing the highest frequency in the Midwest and the lowest in the South, and no significant publication bias detected.
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Background/objectives: Trypanosomiasis and bovine babesiosis correspond to important diseases that cause great economic losses, but there are still no studies evaluating their occurrence in herds of dairy cattle in Ceará. The aim of this study was to perform molecular diagnosis of the main hemoparasites of dairy cows in the microregion of the central hinterland of Ceará.

Methods: For the molecular diagnosis of parasites, genomic material was extracted and polymerase chain reaction directed to the cdCatL-like gene for and SS rRNA of and was performed.

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Background/objectives: Approximately 25% of the world's population and more than 60% of patients with type 2 diabetes (T2D) have metabolic-dysfunction-associated steatotic liver disease (MASLD). The association between these pathologies is an important cause of morbidity and mortality in Brazil and worldwide due to the high frequency of advanced fibrosis and cirrhosis. The objective of this study was to determine the epidemiologic and clinical-laboratory profile of patients with T2D and MASLD treated at an endocrinology reference service in a state in northeastern Brazil, and to investigate the association of liver fibrosis with anthropometric and laboratory measurements.

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Increasing pollination possibilities in species: in vitro and in vivo viability of cryopreserved pollen to address flowering asynchrony.

3 Biotech

December 2024

Embrapa Southeastern Livestock, Brazilian Agricultural Research Corporation, Rodovia Washington Luís, Km 234, CP 339, São Carlos, SP 13560-970 Brazil.

is a vital forage and turf grass in tropical and subtropical regions, yet its breeding programs face challenges due to the lack of natural flowering synchronization between some parent species. Pollen cryopreservation offers a potential solution to this issue. This study aimed to adapt a cryopreservation protocol for the pollen of , , and , and to evaluate the viability of cryopreserved pollen grains (CPG) for hybridization purposes.

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The lack of vaccines shows the need for alternative leishmaniasis treatments. study previously demonstrated the leishmanicidal activity of extracts. This study describes for the first time, the antileishmanial activity of extracts in infected Balb/c mice and its immunomodulatory effect.

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Background: Some odontogenic cysts (OCs) and odontogenic tumors (OTs) are infiltrative and often recur, causing bone destruction and tooth loss. In the elderly, in particular, these injuries cause significant morbidity, making rehabilitation difficult and compromising the quality of life of these individuals. Objective: To determine the prevalence and demographic characteristics of OCs, non-odontogenic cysts (NOCs), and OTs diagnosed in an elderly Brazilian population (≥60 years).

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Structure-based virtual screening and drug repurposing studies indicate potential inhibitors of bovine papillomavirus E6 oncoprotein.

Microbiol Immunol

December 2024

Laboratory of Molecular Genetics and Biotechnology, Department of Biology, Center for Biological and Health Sciences, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil.

Bovine papillomavirus type 1 (BPV1) is an oncogenic virus that causes lesions and cancer in infected cattle. Despite being one of the most studied genotypes in the family and occurring in herds worldwide, there are currently no vaccines or drugs for its control. The viral E6 oncoprotein plays a crucial role in infection by this virus, making it a promising target for the development of new therapies.

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Inhibitory activity of Euterpe oleracea Mart. fruit extract in West Nile virus infection.

Microb Pathog

December 2024

Center for Biological and Health Sciences, University of Pará State, Travessa Perebebuí 2623, Belém, 66095-662, Brazil; Section for Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Rodovia BR-316 km 7 s/n, Ananindeua, 67030-000, Brazil. Electronic address:

West Nile virus (WNV) is a neurovirulent arbovirus whose epidemic capacity is enhanced by the wide occurrence of competent vectors and susceptible avian amplifying hosts. In this study, we investigated the antiviral potential of Euterpe oleracea Mart. fruit extract (EoFE) in WNV infection of monkey kidney (Vero) cell cultures.

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Article Synopsis
  • - Leprosy is a chronic infectious disease that affects peripheral nerves, leading to pain and decreased sensitivity, which can impair balance; measures such as center of pressure (COP) oscillations are important for evaluating balance in patients.
  • - The study aimed to validate the use of inertial sensors for assessing balance in leprosy patients by comparing the results to those obtained from a force platform.
  • - Results showed significant differences in balance parameters between leprosy patients and healthy controls, with the inertial sensors confirming the findings from the force platform, indicating their potential as a portable balance assessment tool.
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Oral Species and MRSA Strains in Patients with Orofacial Clefts Undergoing Surgical Rehabilitation Diagnosed by MALDI-TOF MS.

Pathogens

September 2024

Department of Morphology and Pathology & Biotechnology Graduate Program (PPGBiotec), Center for Biological and Health Sciences (CCBS), Federal University of São Carlos (UFSCar), Km 235 Washington Luís Road, São Carlos 13565-905, SP, Brazil.

Article Synopsis
  • - The study analyzed the presence and behavior of oral bacteria in 59 patients with orofacial clefts receiving surgical rehabilitation, focusing on factors like age, gender, and surgical history.
  • - Salivary samples were collected and tested using traditional microbiological methods and advanced techniques to identify MRSA strains and overall staphylococcal colonization, with 55.9% of patients showing signs of colonization at different points.
  • - Factors influencing oral bacterial colonization during treatment included surgical asepsis practices, the potential for new bacterial colonization in treated areas, and the patients' repeat visits to medical facilities, which might elevate MRSA acquisition risk.
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Introduction: Root canal retreatment is carried out in cases where previous endodontic therapies failed and involves the removal of root canal filling materials, followed by cleaning, shaping, and obturating of the canals.

Aims: : The objective of this study was to collect information regarding attitudes, methods, and materials employed during the non-surgical endodontic retreatment (NSER) by general dentists working in Sousse Governorate, Tunisia.

Materials And Methods: A descriptive cross-sectional survey was conducted among 147 general dentists working in the Sousse Governorate, Tunisia, from May to November 2021.

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Introduction: Levothyroxine (L-T4) monotherapy is the standard of care for the treatment of hypothyroidism. A minority of the L-T4-treated patients remain symptomatic and report better outcomes with combination therapy that contains liothyronine (L-T3) or with desiccated thyroid extract (DTE).

Goal: To assess patient preferences in the treatment of hypothyroidism.

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Ecological networks in savannas reflect different levels of hydric stress in adjacent palm swamp forest ecosystems.

Sci Rep

September 2024

Graduate Program in Animal Biodiversity, Institute of Biological Sciences, Federal University of Goiás, Goiânia, 74690-900, Brazil.

Palm swamp forests are wetland ecosystems typical of the Brazilian Cerrado, which in recent decades have undergone intense changes due to land use alterations and climate change. As a result of these disturbances, many palm swamps have been experiencing significant drying, which can also affect adjacent vegetation. In the present study, we evaluated whether the drying of palm swamps affects the structure of plant-herbivore networks located in adjacent savanna areas in Brazil.

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Objective: Glucagon-like peptide-1 (GLP1) and leptin (Lep) are afferent signals that regulate energy metabolism. Lactational hypernutrition results in hyperphagia and adiposity in adult life, and these events can be prevented by exercise. We evaluated the effects of swimming training on hypothalamic (GLP1-R) and Lep receptor (Lep-R) gene expressions in lactational hypernutrition-induced obesity.

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This study aimed to develop a novel ureasil-polyether transdermal hybrid matrix (U-PEO) loaded with concentrated extract (AMCE), which exhibits potent anti-inflammatory activity. The extract was obtained by maceration, a method that allowed for the extraction of a high concentration of flavonoids (39.27 mg/g of extract).

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Status of β-Adrenoceptor Signal Transduction System in Cardiac Hypertrophy and Heart Failure.

Rev Cardiovasc Med

September 2023

Heart Biophysics Laboratory, Department of Physiology, Center for Biological and Health Sciences, Federal University of Sergipe, 73330 Sergipe, Brazil.

Although -adrenoceptor ( -AR) signal transduction, which maintains cardiac function, is downregulated in failing hearts, the mechanisms for such a defect in heart failure are not fully understood. Since cardiac hypertrophy is invariably associated with heart failure, it is possible that the loss of -AR mechanisms in failing heart occurs due to hypertrophic process. In this regard, we have reviewed the information from a rat model of adaptive cardiac hypertrophy and maladaptive hypertrophy at 4 and 24 weeks after inducing pressure overload as well as adaptive cardiac hypertrophy and heart failure at 4 and 24 weeks after inducing volume overload, respectively.

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Hair collection protocol in 12-month-old infants.

Compr Psychoneuroendocrinol

August 2024

Human Developmental Sciences Graduate Program, Center for Biological and Health Sciences, Mackenzie Presbyterian University, Rua da Consolacao, 930, Building 28, 9th floor, Sao Paulo, 01302-000, Brazil.

Purpose: Most studies assessing hair cortisol were conducted with adults. As specific guidelines for infant hair collection are lacking, we developed a hair collection protocol for 12-month-old infants and assessed its acceptability and feasibility.

Results: Out of the total ( = 45), 95.

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Volatile oils or essential oils (EOs) were extracted from three samples (labeled as A, B, and C) in September 2018 and February 2019; the extraction process involved hydrodistillation of the leaves. The chemical compositions of the EOs were analyzed using gas chromatography-mass spectrometry (GC/MS). The volatile components were identified by comparing their retention indices and mass spectra with standard substances documented in the literature (ADAMS).

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Diabetes mellitus is a metabolic disorder commonly associated with atherosclerosis. Plants with therapeutic potential, such as Kunth, emerge as effective alternatives for treating these diseases. Therefore, this work aims to analyze the antihyperglycemic and antidyslipidemic potential of the hydroalcoholic extract of Kunth (ELo) in alloxan-diabetic rats.

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Article Synopsis
  • * A cross-sectional approach was used, enrolling 1,138 individuals over nearly two years, with tests revealing a 20% prevalence of IgM antibodies and a remarkable 97.5% for IgG antibodies against HSV-1.
  • * The presence of HSV-1 DNA was confirmed in over a quarter of individuals with positive IgM results, indicating a significant silent prevalence of the virus within this community, particularly in individuals with certain urinary and genital symptoms.
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