Biofidelity Assessment of the WIAMan Thorax by a Comparative Study With Hybrid III, THOR, and PMHS in Frontal Sled Testing.

The Warrior Injury Assessment Manikin (WIAMan) anthropomorphic test device (ATD) has been originally developed to predict and prevent injuries for occupants in military vehicles, in an underbody blast environment. However, its crash performance and biofidelity of the thoracic region have not been explored. The aim of this study was to determine and evaluate the WIAMan thoracic responses in a typical frontal sled test.

Human Lumbar Spine Injury Risk in Dynamic Combined Compression and Flexion Loading.

Anticipating changes to vehicle interiors with future automated driving systems, the automobile industry recently has focused attention on crash response in novel postures with increased seatback recline. Prior research found that this posture may result in greater risk of lumbar spine injury in the event of a frontal crash. This study developed a lumbar spine injury risk function (IRF) that estimated injury risk as a function of simultaneously applied compression force and flexion moment.

Development and Performance Evaluation of an IoT-Integrated Breath Analyzer.

Although alcohol consumption may produce effects that can be beneficial or harmful, alcohol consumption prevails among communities around the globe. Additionally, alcohol consumption patterns may be associated with several factors among communities and individuals. Numerous technologies and methods are implemented to enhance the detection and tracking of alcohol consumption, such as vehicle-integrated and wearable devices.

Investigation of factors influencing submarining mitigation with child booster seats.

Objective: Automobile booster seats are intended to improve belt fit for children that are too large for a harness-style child restraint, but not yet big enough to fit properly in an adult seat belt. Our objective was to prospectively study the relationship between booster seat design and interaction with the seat belt (specifically, submarining risk) for a child occupant using computer simulation of automobile crash events.

Methods: Frontal-impact simulations were performed with a 6-year-old child human body model.

Quantifying Arms and Legs Contributions during Repetitive Electrically-Assisted Sit-To-Stand Exercise in Paraplegics: A Pilot Study.

Execution of Sit-to-Stand (SitTS) in incomplete spinal cord injury (SCI) patients involves motor function in both upper and lower extremities. The use of arm support, in particular, is a significant assistive factor while executing SitTS movement in SCI population. In addition, the application of functional electrical stimulation (FES) onto quadriceps and gluteus maximus muscles is one of the prescribed management for incomplete SCI to improve muscle action for simple lower limb movements.

Abnormal proximal-distal interactions in upper-limb of stroke survivors during object manipulation: A pilot study.

Despite its importance, abnormal interactions between the proximal and distal upper extremity muscles of stroke survivors and their impact on functional task performance has not been well described, due in part to the complexity of upper extremity tasks. In this pilot study, we elucidated proximal-distal interactions and their functional impact on stroke survivors by quantitatively delineating how hand and arm movements affect each other across different phases of functional task performance, and how these interactions are influenced by stroke. Fourteen subjects, including nine chronic stroke survivors and five neurologically-intact subjects participated in an experiment involving transport and release of cylindrical objects between locations requiring distinct proximal kinematics.

Generating Human Arm Kinematics Using Reinforcement Learning to Train Active Muscle Behavior in Automotive Research.

Computational human body models (HBMs) are important tools for predicting human biomechanical responses under automotive crash environments. In many scenarios, the prediction of the occupant response will be improved by incorporating active muscle control into the HBMs to generate biofidelic kinematics during different vehicle maneuvers. In this study, we have proposed an approach to develop an active muscle controller based on reinforcement learning (RL).

Alterations in motor modules and their contribution to limitations in force control in the upper extremity after stroke.

The generation of isometric force at the hand can be mediated by activating a few motor modules. Stroke induces alterations in motor modules underlying steady-state isometric force generation in the human upper extremity (UE). However, how the altered motor modules impact task performance (force production) remains unclear as stroke survivors develop and converge to the three-dimensional (3D) target force.

Assessing the Effects of Geniculate Artery Embolization in a Nonsurgical Animal Model of Osteoarthritis.

Purpose: To create a nonsurgical animal model of osteoarthritis (OA) to evaluate the effects of embolotherapy during geniculate artery embolization (GAE).

Materials And Methods: Fluoroscopy-guided injections of 700 mg of sodium monoiodoacetate were performed into the left stifle in 6 rams. Kinematic data were collected before and after induction.

A Review of Finite Element Models of Ligaments in the Foot and Considerations for Practical Application.

Finite element (FE) modeling has been used as a research tool for investigating underlying ligaments biomechanics and orthopedic applications. However, FE models of the ligament in the foot have been developed with various configurations, mainly due to their complex three-dimensional geometry, material properties, and boundary conditions. Therefore, the purpose of this review was to summarize the current state of finite element modeling approaches that have been used in the field of ligament biomechanics, to discuss their applicability to foot ligament modeling in a practical setting, and also to acknowledge current limitations and challenges.

Methodology to measure seat belt fit in relation to skeletal geometry using an upright open MRI.

Objective: Poor seat belt fit can result in submarining behavior and injuries to the lower extremity and abdomen. While previous studies have explored seat belt fit relative to skeletal landmarks using palpation, medical imaging remains the gold standard for visualizing and locating skeletal landmarks and soft tissues. The goal of this study was to create a method to image automotive postures and seat belt fit from the pelvis to the clavicle using an Upright Open MRI.

Integrating Human and Nonhuman Primate Data to Estimate Human Tolerances for Traumatic Brain Injury.

Traumatic brain injury (TBI) contributes to a significant portion of the injuries resulting from motor vehicle crashes, falls, and sports collisions. The development of advanced countermeasures to mitigate these injuries requires a complete understanding of the tolerance of the human brain to injury. In this study, we developed a new method to establish human injury tolerance levels using an integrated database of reconstructed football impacts, subinjurious human volunteer data, and nonhuman primate data.

Evaluation of a diverse population of morphed human body models for prediction of vehicle occupant crash kinematics.

Morphing can be used to alter human body models (HBMs) to represent a diverse population of occupants in car crashes. The mid-sized male SAFER HBM v9 was parametrically morphed to match 22 Post Mortem Human Subjects, loaded in different configurations. Kinetics and kinematics were compared for the morphed and baseline HBMs.

Sensory tricks modulate corticocortical and corticomuscular connectivity in cervical dystonia.

Objective: To examine interactions between cortical areas and between cortical areas and muscles during sensory tricks in cervical dystonia (CD).

Methods: Thirteen CD patients and thirteen age-matched healthy controls performed forewarned reaction time tasks, sensory tricks, and two tasks replicating aspects of the tricks (moving necks/arms). Control subjects mimicked sensory tricks.

Effect of Temperature and Freezing on Human Adipose Tissue Material Properties Characterized by High-Rate Indentation: Puncture Testing.

The characterization of human subcutaneous adipose tissue (SAT) under high-rate loading is valuable for development of biofidelic finite element human body models (FE-HBMs) to predict seat belt-pelvis interaction and injury risk in vehicle crash simulations. While material characterization of SAT has been performed at 25 °C or 37 °C, the effect of temperature on mechanical properties of SAT under high-rate and large-deformation loading has not been investigated. Similarly, while freezing is the most common preservation technique for cadaveric specimens, the effect of freeze-thaw on the mechanical properties of SAT is also absent from the literature.

Evaluation of the Effectiveness of Newer Helmet Designs with Emergent Shell and Padding Technologies Versus Older Helmet Models for Preserving White Matter Following a Season of High School Football.

We aimed to objectively compare the effects of wearing newer, higher-ranked football helmets (HRank) vs. wearing older, lower-ranked helmets (LRank) on pre- to post-season alterations to neuroimaging-derived metrics of athletes' white matter. Fifty-four high-school athletes wore an HRank helmet, and 62 athletes wore an LRank helmet during their competitive football season and completed pre- and post-season diffusion tensor imaging (DTI).

Is optimized restraint system for an occupant with obesity different than that for a normal BMI occupant?

Objective: To optimize the components of restraint systems for protecting obese (BMI = 35 kg/m) and normal BMI (BMI = 25) human body models (HBMs) in frontal crash simulations, and to compare the two optimized designs.

Methods: The Life Years Lost metric, which incorporates the risk of injury and long-term disability to different body regions, was used as the optimization objective function. Parametric simulations, sampled from a 15-parameter design space using the Latin Hypercube technique, were performed and metamodels of the HBM responses were developed.

Toward subject-specific evaluation: methods of evaluating finite element brain models using experimental high-rate rotational brain motion.

Computational models of the brain have become the gold standard in biomechanics to understand, predict, and mitigate traumatic brain injuries. Many models have been created and evaluated with limited experimental data and without accounting for subject-specific morphometry of the specimens in the dataset. Recent advancements in the measurement of brain motion using sonomicrometry allow for a comprehensive evaluation of brain model biofidelity using a high-rate, rotational brain motion dataset.

Effect of various restraint configurations on submarining occurrence across varied seat configurations in autonomous driving system environment.

Objective: Self-driving technology will bring novelty in vehicle interior design and allow for a wide variety of occupant seating choices. Previous studies have shown that the increased risk of submarining exhibited by reclined occupants cannot be fully mitigated by changes in the seat configuration alone. This study aims to investigate the effects of three restraint countermeasures on cases with marginal submarining events and estimate their effect on submarining risk and injury prediction metrics.

Force-limiting and the mechanical response of natural turfgrass used in the National Football League: A step toward the elimination of differential lower limb injury risk on synthetic turf.

Lower limb injury rate in the National Football League (NFL) is greater on synthetic turf than on natural turfgrass. Foot loading in potentially injurious situations can be mitigated by damage to natural turfgrass that limits the peak load by allowing relative motion between the foot and the ground. Synthetic turf surfaces do not typically sustain such damage and thus lack such a load-limiting mechanism.

Development and multi-level validation of a computational model to predict traumatic aortic injury.

Traumatic aortic injury (TAI) is one of the leading causes of fatalities in blunt impact. However, there is no consensus on the injury mechanism of TAI in traffic accidents, mainly due to the complexity of occurrence scenarios and limited real-world crash data relevant to TAI. In this study, a computational model of the aorta with nonlinear mechanical characteristics and accurate morphology was developed and integrated within a thorax finite element model that included all major anatomical structures.

Evaluation and Validation of Thorax Model Responses: A Hierarchical Approach to Achieve High Biofidelity for Thoracic Musculoskeletal System.

As one of the most frequently occurring injuries, thoracic trauma is a significant public health burden occurring in road traffic crashes, sports accidents, and military events. The biomechanics of the human thorax under impact loading can be investigated by computational finite element (FE) models, which are capable of predicting complex thoracic responses and injury outcomes quantitatively. One of the key challenges for developing a biofidelic FE model involves model evaluation and validation.