Post-surgical outcome and prognostic factors in canine malignant melanomas of the haired skin: 87 cases (2003-2015).

The medical records of 87 dogs treated with surgery for cutaneous malignant melanoma (CMM) of the haired skin were retrospectively reviewed for overall survival time (OST), progression-free survival time (PFS), and prognostic factors. The post-surgery median PFS and median OST were 1282 days and 1363 days, respectively. The post-surgery metastatic rate was 21.

Effect of Variations in Stent Placement on Outcome of Endoluminal Stenting for Canine Tracheal Collapse.

The study's objective was to determine effects of relative size and placement location of endoluminal stents on incidence of complications and survival for canine tracheal collapse. Measurements were obtained on lateral radiographs before and after stenting to determine percent of the trachea occupied by the stent. These values were monitored over time and compared to complication rates and survival.

Liver lobe torsion in pet rabbits: clinical consequences, diagnosis, and treatment.

This article reviews diagnosis and management of liver lobe torsion in rabbits. Practitioners should recommend initial diagnostics including radiographs and blood work on rabbits presenting with nonspecific signs of gastrointestinal (GI) stasis to better determine possible etiology and make the best treatment recommendations. If hepatic enzyme elevation is found in a rabbit with GI stasis, abdominal ultrasound is recommended to rule out liver lobe torsion.

Targeting the unfolded protein response, XBP1, and the NLRP3 inflammasome in fibrosis and cancer.

Increasing health care costs in the US are due in a large part to the increasing prevalence of chronic diseases in an aging population. Current therapeutic strategies for treating chronic diseases alleviate symptoms allowing patients to live longer with these diseases, but they do little, however, to alter the underlying disease course. Recent advances in molecular biology are revealing new drug targets that may significantly alter the course of these diseases and, as a result, offer economic relief from burgeoning health care costs.

Upper respiratory tract endoscopy in the cat: a minimally invasive approach to diagnostics and therapeutics.

Clinical Challenges: Endoscopy of the feline upper respiratory tract has always taken a bit of a back seat to exploration of the canine nose and paranasal sinuses, pharynx and trachea, due to some anatomic limitations and lack of availability of appropriate-sized equipment.

Practical Relevance: With proper training, however, even the inexperienced endoscopist can find that endoscopy and endoscopic surgery can be of tremendous utility in feline practice. What had previously been largely off-limits sites, in terms of direct visualization and surgical intervention, the feline rhinarium, paranasal sinuses, pharynx and trachea are now anatomic areas that can be effectively visualized in most clinical scenarios.

Intravitreal cidofovir injection for the management of chronic glaucoma in dogs.

Objective: The objective of this retrospective study was to determine whether an intravitreal injection of 562.5 ug of cidofovir was effective in lowering the intraocular pressure (IOP) in chronically glaucomatous avisual canine eyes.

Patients: This study reviews the medical records of 167 canine patients diagnosed with chronic glaucoma between 2006 and 2011.

Intraoperative antinociception and postoperative analgesia following epidural anesthesia versus femoral and sciatic nerve blockade in dogs undergoing stifle joint surgery.

Objective: To compare analgesic efficacy of preoperative epidural anesthesia with efficacy of femoral and sciatic nerve blockade in dogs undergoing hind limb orthopedic surgery.

Design: Prospective randomized blinded clinical study.

Animals: 22 dogs requiring stifle joint surgery.