5 results match your criteria: "Center for Advanced Integrated Renal Science[Affiliation]"

Background: Several studies have reported that lower body mass index (BMI) is associated with high mortality in patients with chronic kidney disease (CKD). Rate of infection-related death in CKD patients is increasing. However, the relationship between BMI and infection-related death is unclear.

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Background: Anemia greatly affects the development of renal and cardiovascular outcomes in chronic kidney disease (CKD) patients. However, the impact based on CKD stage remains unclear.

Methods: We prospectively followed 2,602 Japanese CKD patients under the care of nephrologists.

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Background: Previous studies established a J-shaped association between blood pressure (BP) and cardiovascular disease (CVD) in chronic kidney disease (CKD), and the different clinical profiles of CVD by ethnicity. However, the adequately lower BP target remains unclear in Asian patients with CKD.

Methods: This prospective observational study included 2,655 Japanese outpatients with CKD under nephrologist care who met the inclusion criteria, namely estimated glomerular filtration rate <60 mL/min and/or presenting proteinuria.

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Article Synopsis
  • The study investigates the impact of hypertensive nephropathy (HN) on cardiovascular disease (CVD) and mortality among non-diabetic chronic kidney disease (CKD) patients.
  • It involved 2,692 CKD patients from various clinics, analyzing CVD risk factors, all-cause mortality, and the progression to end-stage renal failure over an average follow-up of 22.6 months.
  • Findings revealed that HN significantly increases the risk of CVD events and death compared to primary renal disease, emphasizing the importance of HN in clinical settings for CKD patients.
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