2 results match your criteria: "Center Hospital of Xiangfan[Affiliation]"

[Serum leptin level in patients with obstructive sleep apnea-hypopnea syndrome].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi

April 2005

Department of Otorhinolaryngology, Center Hospital of Xiangfan, Hubei 441021, China.

Objective: To investigate the effect of uvulopalatopharyngoplasty on changes of serum leptin levels in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS).

Methods: Sixty-one patients with OSAHS diagnosed by polysomnography were treated with uvulopalatopharyngoplasty. Pretreatment and post-uppp serum leptin concentrations in patients with OSAHS and in BMI-matched controls were measured by radioimmunoassay.

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[The role of heat shock protein 70 and its autoantibody in experimental autoimmune inner ear disease].

Zhonghua Er Bi Yan Hou Ke Za Zhi

February 2000

Department of Otorhinolaryngology, Center Hospital of Xiangfan, Hubei 441021, China.

Objective: To examine the effect of antigen stimulation on induction of the heat shock protein 70(HSP70) in the guinea pig cochlea and to explore the role of HSP70 and its autoantibody in the pathogenesis and diagnosis of autoimmunize inner ear disease (AIED).

Methods: To establish the animal model of AIED, homologous crude inner ear antigen was used to immunize the guinea pig. The expression of HSP70 was detected by immunocytochemistry and the relative staining densities were quantified with a light microscope image analysis system.

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