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The Glucocorticoid Taper: A Primer for the Clinicians.
Indian J Endocrinol Metab
August 2024
Department of Endocrinology, Cedar Super Specialty Clinic, Delhi, India.
Article Synopsis
- - Glucocorticoid (GC) therapy can effectively treat serious inflammatory disorders but carries risks of side effects, requiring the lowest effective dose for the shortest duration to minimize these risks.
- - Tapering GC therapy is crucial to avoid adrenal insufficiency by allowing the hypothalamic-pituitary-adrenal (HPA) axis to recover while monitoring for disease reactivation; higher doses can be tapered quickly, but once close to physiologic doses, tapering must slow down.
- - Patients on GCs need to be aware of potential adrenal crisis during illnesses and should increase their doses accordingly while carrying a steroid alert card to inform healthcare providers.