842 results match your criteria: "Cauda Equina and Conus Medullaris Syndromes"

Background: Advances in local and systemic therapies continue to improve overall survival for patients with cancer, increasing the incidence of spine metastases. Up to 15% of patients with solid tumors develop spinal metastases. Spinal metastases can be particularly devastating for quality of life given the potential pain, neurological deficits from spinal cord compression or cauda equina syndrome, spinal instability, and pathological fractures that may result.

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  • Cauda equina syndrome (CES) in beta thalassemia patients, often linked to extramedullary hematopoiesis, is rare and presents treatment challenges, with limited documented cases showing varied outcomes.!* -
  • A case of a 29-year-old male with beta thalassemia showed symptoms like lower back pain, numbness, and urinary issues; MRI indicated cauda equina compression due to abnormal blood cell production.!* -
  • Surgical interventions provided some relief for the patient's pain and symptoms, but long-term issues like sensory impairment and bladder control problems remain, highlighting the need for better management guidelines in such complex cases.!*
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A Morphometric Study on the Dimensions of the Vertebral Canal and Intervertebral Discs from Th1 to S1 in Cats and Their Relevance for Spinal Diseases.

Vet Sci

September 2024

Faculty of Veterinary Medicine, Institute of Veterinary Anatomy, Histology and Embryology, Leipzig University, An den Tierkliniken 43, D-04103 Leipzig, Germany.

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  • * A 63-year-old male with CES symptoms—urinary and fecal retention, and altered genital sensation—was found to have metastatic lesions in his sacral spine and a primary lung lesion indicated by CT and MRI scans.
  • * The patient was diagnosed with metastatic neuroendocrine carcinoma after a lymph node biopsy and underwent treatment including steroids, chemotherapy, and radiation, highlighting the need for thorough evaluation for metastasis in CES cases.
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Microsurgical treatment of spinal intradural capillary hemangioma: A consecutive case series of 18 patients and literature review.

Clin Neurol Neurosurg

November 2024

Department of Neurosurgery, Shanghai Institute of Neurosurgery, Changzheng Hospital, Naval Medical University, Shanghai 200003, PR China. Electronic address:

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Background: To explore the surgical outcome of enlarged posterior column osteotomy (EPCO) plus intervertebral cage strutting (ICS) for patients with lumbosacral nerve bowstring disease (BSD).

Methods: The clinical data of 27 patients with BSD that surgically treated with EPCO plus ICS from January 2018 to March 2021 were retrospectively reviewed. Patient demographics including age, gender, body mass index (BMI), duration, length of hospital stay, SF-36 were recorded.

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Background: Schwannomas and meningiomas are intradural extramedullary spinal tumors which are regularly encountered in the neurosurgical clinic. These tumors cause neurological deficit by compression on the spinal cord and commonly pain when affecting the cauda equina. The traditional treatment with standard laminectomy (SL) can cause instability to the dorsal segments of the spinal column, and the less invasive option of hemilaminectomy (HL) has therefore been developed.

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The predictive value of intraoperative bulbocavernosus reflex monitoring for postoperative voiding function in patients with conus medullaris and cauda equina tumors: a retrospective single center study.

Spine J

December 2024

Department of Neuroelectrophysiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. Electronic address:

Article Synopsis
  • Surgical resection is the main treatment for conus medullaris and cauda equina tumors, but achieving complete removal can be difficult and risky, making intraoperative neurophysiological monitoring (IONM) crucial for safer procedures.
  • This study focuses on the effectiveness of monitoring the bulbocavernosus reflex (BCR) during surgeries to improve outcomes for patients undergoing CMCET resection.
  • The results showed that specific measures of BCR waveform reductions were strongly linked to postoperative voiding dysfunction, providing a potential method to predict these complications.
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  • - A literature review was conducted to explore whether neuron-specific enolase (NSE) could indicate the absence of spinal cord or nerve root compression, examining a total of 132 papers.
  • - Only 4 studies provided relevant data on the use of NSE as a clinical marker, which were analyzed for authors, publication details, patient demographics, outcomes, and study limitations.
  • - The conclusion is that there is currently no evidence supporting the use of NSE measurements in clinical settings to rule out significant spinal compression.
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  • The study investigated the safety and effectiveness of stereotactic ablative body radiotherapy (SABR) for re-treating spinal metastases that had previously received radiotherapy.
  • It analyzed data from patients at three Australian centers, focusing on local control rates and serious complications over a median follow-up of 2.6 years.
  • Results showed that the majority of patients had good tumor control and survival rates, suggesting that SABR is a viable option for patients with persistent spinal issues after previous treatments.
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External Beam Radiation Therapy for Palliation of Symptomatic Bone Metastases: An ASTRO Clinical Practice Guideline.

Pract Radiat Oncol

September 2024

Department of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, Massachusetts.

Purpose: This guideline provides evidence-based recommendations for palliative external beam radiation therapy (RT) in symptomatic bone metastases.

Methods: The ASTRO convened a task force to address 5 key questions regarding palliative RT in symptomatic bone metastases. Based on a systematic review by the Agency for Health Research and Quality, recommendations using predefined consensus-building methodology were established; evidence quality and recommendation strength were also assessed.

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Pneumorrhachis (PR) is an uncommon condition characterized by the accumulation of air within the spinal canal. This finding may occur due to various causes, mostly after trauma and medical procedures. It can manifest with various features depending on the underlying cause, the location, and the extent of the air trapped.

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Background: Cauda equina syndrome (CES) is a consequence of a variety of etiologies. CES is most commonly due to compression of the thecal sac and nerve roots by a massive disc herniation. However, it rarely presents secondary to aortic occlusion.

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  • The text discusses cauda equina syndrome (CES), conus medullaris syndrome (CMS), and conditions that mimic sciatica, emphasizing the complexities in diagnosing and treating these conditions for spine surgeons.
  • A systematic literature review resulted in 43 relevant studies, leading to seven consensus statements developed through discussions in international meetings.
  • The study recommends standardized definitions, urgent MRI for suspected CES, prompt surgical decompression within 48 hours, and awareness of other conditions that can present similarly to sciatica.
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Electrodiagnostic testing in dogs with disorders of the spinal cord or cauda equina.

Vet J

April 2024

Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 1060 William Moore Dr, Raleigh, NC 27607, USA. Electronic address:

Electrodiagnostic (EDX) testing is uncommonly utilized in dogs other than for investigation of disorders of the neuromuscular system. In dogs with diseases affecting the spinal cord or cauda equina, EDX testing can provide functional data complementary to imaging information that together can guide therapeutic and management approaches. Additionally, in some clinical scenarios, EDX testing prior to advanced imaging is integral to identifying if there is spinal cord or cauda equina involvement and can aid in determining the appropriate diagnostic path.

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Recurrent Acute Disseminated Encephalomyelitis Presenting as Conus Medullaris Syndrome: A Case Report.

Medicina (Kaunas)

January 2024

Department of Physical Medicine and Rehabilitaiton, Korea University Guro Hospital, Seoul 08308, Republic of Korea.

Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disorder that typically follows an infection or recent vaccination. Symptoms such as encephalopathy and focal neurological deficits appear weeks after the initial illness, leading to swift and progressive neurological decline. While ADEM in the brain has been well documented, reports of ADEM, specifically in the spinal cord, are relatively limited.

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  • Spinal epidural hematoma is a rare but serious condition that can lead to spinal cord issues, occurring in about 1 in a million patients yearly.
  • A 69-year-old man experienced leg pain and weakness after falling, and MRI scans revealed a hematoma compressing nerve roots due to an L2-L3 fracture.
  • Surgeons treated him through a procedure that involved hematoma aspiration and spinal stabilization, leading to symptom relief and a smooth recovery, but he later developed left leg pain due to coxarthrosis.
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Background: Despite the encouraging results of the SCORAD trial, single fraction radiotherapy (SFRT) remains underused for patients with complicated bone metastases with rates as low as 18-39%. We aimed to evaluate the incidence and treatment patterns of these metastases in patients being referred to a tertiary centre for palliative radiotherapy.

Materials And Methods: We performed a retrospective review of all bone metastases treated at our centre from January 2013 until December 2017.

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Background: Spinal subdural hematoma (SSH) is a rare cause of compression of the neutral elements of the spinal cord. However, little is known about the presentation of acute SSH after lumbar spine surgery. The reason for this may be that symptomatic SSH occurs rarely and is not given enough attention by spine surgeons.

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Introduction: Conus medullaris syndrome (CMS) is a distinctive spinal cord injury (SCI), which presents with varying degrees of upper motor neuron signs (UMNS) and lower motor neuron signs (LMNS). Herein, we present a case with a burst fracture injury at the proximal Conus Medullaris (CM).

Case Presentation: A 48-year-old Taiwanese male presenting with lower back pain and paraparesis was having difficulty standing independently after a traumatic fall.

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Background: Cauda Equina Syndrome (CES) after Combined Spinal-Epidural Anesthesia (CSEA) is a rare disease that most of the time need surgery to relieve spinal cord compression.

Case Presentation: A 34-year-old male patient underwent a procedure for prolapse and hemorrhoids (PPH) under CSEA. Anesthesia and surgery were uneventful.

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Article Synopsis
  • This study investigated neurological variations in patients with epiconus, conus medullaris, and cauda equina syndromes after acute thoracolumbar spinal injuries.
  • It involved 87 patients who were categorized based on the location of the narrowest part of their spinal canal, identifying 22 with epiconus, 37 with conus medullaris, and 25 with cauda equina involvement.
  • Although more patients initially had a narrowed epiconus, by the end of the study, neurological recovery was similar across all three syndromes, highlighting the importance of anatomical classification in understanding these conditions.
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