2,759 results match your criteria: "Catscratch Disease"
Cat scratch disease in children with nocturnal fever: A case report.
World J Clin Cases
December 2024
Department of Pediatric Intensive Care Unit, Rainbow Hospital of Xianyang (Children's Hospital of Xianyang), Xianyang 721000, Shaanxi Province, China.
Background: Cat scratch disease (CSD) is the most common human infection caused by (). The main manifestation is self-limited lymphadenopathy that primarily affects adolescents, and typically resolves without treatment within 2-4 months. However, individuals with compromised immune systems or immunodeficiency require specific antibacterial therapy following diagnosis.
View Article and Find Full Text PDFUnilateral Exudative Retinal Detachment and Uveitis Accompanied by a Large Subretinal Deposit on the Macula Secondary to Bartonella Henselae Infection.
Diagnostics (Basel)
December 2024
Beijing Children's Hospital, Capital Medical University, Beijing 100070, China.
Bartonella henselae is a Gram-negative bacillus, mainly parasitizing on cats. When a child is scratched by a cat, they may present with the disease symptoms including regional lymphadenopathy, malaise, fever, and splenomegaly, which is known as cat-scratch disease (CSD). Ocular manifestations occur in 5-10% of patients with CSD.
View Article and Find Full Text PDFViable but nonculturable state in the zoonotic pathogen induced by low-grade fever temperature and antibiotic treatment.
Front Cell Infect Microbiol
December 2024
Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences, Lanzhou, China.
The zoonotic pathogen is responsible for diverse human diseases, from mild to life-threatening, but it often eludes detection in culture-based assays. This study investigates the potential of to enter a viable but nonculturable (VBNC) state when exposed to human fever temperature or antibiotics, with this state confirmed by successful resuscitation. Viability was assessed using SYBR Green I/PI staining and propidium monoazide-quantitative polymerase chain reaction (PMA-qPCR), while culturability was determined through colony-forming unit (CFU) counting on blood agar plates.
View Article and Find Full Text PDFDifferential vasoproliferative traits of strains associated with autotransporter BafA variants.
Microbiol Spectr
November 2024
Laboratory of Bacterial Zoonoses, International Research Center for Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
Article Synopsis
Clinical Presentation of Cat Scratch Disease in Pediatric Patients-A Single-Center Study.
Turk Arch Pediatr
November 2024
Department of Ophthalmology, Medeniyet University Göztepe Prof. Dr. Süleyman Yalçın City Hospital, Kadıköy, İstanbul, Türkiye.
Objective: Cat scratch disease (CSD) is the infectious disease caused by Bartonella henselae. Its typical presentation is regional lymphadenopathy. Also it may present with symptoms related to involved organs or disseminated disease with fever of unknown origin (FUO).
View Article and Find Full Text PDFNeuroretinitis: a comprehensive review on aetiologies, clinical manifestations, and treatment options.
Eye (Lond)
November 2024
Department of Ophthalmology, The Permanente Medical Group, Kaiser Permanente- Northern California, Roseville, CA, USA.
Neuroretinitis connotes a descriptive clinical entity of optic disc oedema in association with macular exudates in a star configuration. Accordingly, it does not indicate a specific aetiology, although cat scratch disease caused by Bartonella henselae is the most common cause. Historically, the recognition of neuroretinitis dates to the early 20 century with the eventual understanding that the optic disc is the primary target of disease with secondary macular involvement.
View Article and Find Full Text PDFA case of generalized cat scratch disease in a patient with ulcerative colitis on immunosuppressive therapy.
Ther Adv Infect Dis
November 2024
Department of Gastroenterology, University Hospital Split, Split, Croatia.
Article Synopsis
Neurobartonelloses: emerging from obscurity!
Parasit Vectors
October 2024
Intracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.
Article Synopsis
- Bartonella species are intracellular bacteria linked to various human diseases, often transmitted through infected bodily fluids or vectors, but infections have been reported without clear contact to animals or insects.
- These bacteria are associated with neurological conditions, including neuroretinitis and encephalitis, primarily linked to species like Bartonella henselae and B. quintana, and can also cause peripheral neuropathies.
- Recent studies have detected Bartonella DNA more frequently in patients with neuropsychiatric disorders, suggesting a potential connection between these infections and conditions such as schizophrenia and psychoses.
First report of Bartonella henselae and Bartonella clarridgeiae carriage in stray cats from Ecuador: Confirmation by sequencing of gltA gene.
Acta Trop
December 2024
One Health Research Group, Universidad de Las Américas, Quito, Ecuador. Electronic address:
A Case of Parinaud Oculoglandular Syndrome in Which DNA Was Detected in the Cornea and Conjunctiva by Polymerase Chain Reaction.
Medicina (Kaunas)
August 2024
Department of Ophthalmology and Visual Sciences, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Nagasaki, Japan.
Article Synopsis
- Parinaud oculoglandular syndrome (POS) is a condition characterized by unilateral eye inflammation and lymphadenopathy, often linked to infections like cat-scratch disease.
- A 29-year-old man developed POS after adopting a stray cat, experiencing symptoms like fever and eye discharge; tests confirmed the presence of the disease-causing DNA.
- After two weeks of oral medication and two months of topical treatment, the patient's eye condition improved significantly, highlighting the value of PCR testing in diagnosing ocular infections related to POS.
Advancements, challenges, and future perspectives in developing feline herpesvirus 1 as a vaccine vector.
Front Immunol
September 2024
Key Laboratory of Animal Biosafety Risk Prevention and Control (North) and Key Laboratory of Veterinary Biological Products and Chemical Drugs of Ministry of Agriculture and Rural Affairs (MARA), Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Article Synopsis
- Cats are the most common companion animals but face threats from infectious diseases and zoonotic pathogens, like those causing human toxoplasmosis and cat-scratch disease.
- Current vaccinations primarily protect against three core diseases: feline panleukopenia, feline herpesvirus, and feline calicivirus, with limited options for other important infections.
- The paper explores the potential of feline herpesvirus as a vaccine vector using advanced technologies like CRISPR/Cas9, discussing its efficacy in expressing other pathogen antigens and addressing existing challenges in its development.
Lymph Node Histology and Metagenomic Sequencing in a child with Cat Scratch Disease.
QJM
September 2024
Department of Pediatric, The People's Hospital of Bozhou, Bozhou, China.
A 4-year-old boy presented with fever and lymphadenopathy. Despite antibiotic treatment for suspected lymphadenitis, there was minimal improvement. A lymph node biopsy revealed granulomas, raising suspicion of cat scratch disease (CSD).
View Article and Find Full Text PDFDetection of Bartonella henselae in feline erythrocytes in Egypt by using Giemsa staining, transmission electron microscopy, and polymerase chain reaction.
Microsc Res Tech
January 2025
Department of Pathology and Clinical Pathology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt.
Article Synopsis
- Bartonella species, particularly Bartonella henselae, are important human pathogens often associated with diseases like cat-scratch disease, primarily originating from infected cats.
- This study utilized light microscopy and transmission electron microscopy (TEM) to investigate the presence of Bartonella in feline blood, revealing intraerythrocytic corpuscles indicative of infection in 18.18% of examined samples.
- While light microscopy and TEM were effective in initial screening, the research emphasizes the necessity of molecular methods, like PCR, for accurate identification and confirmation of specific Bartonella species.
On-host flea phenology and flea-borne pathogen surveillance among mammalian wildlife of the pineywoods of East Texas.
J Vector Ecol
December 2024
Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX, U.S.A.,
Article Synopsis
- Flea-borne diseases like flea-borne typhus and cat scratch disease are increasingly common in Texas, highlighting the need to understand flea ecology for public health protection.
- A study in East Texas involved monthly trapping of mammals, resulting in 101 fleas collected predominantly from Virginia opossums, which had a high infestation rate of 79%.
- The research found that flea populations peaked in spring and identified pathogens in some mammals, suggesting that wildlife may play a significant role in maintaining these disease vectors.
Parinaud Oculoglandular Syndrome Among Female Adults in Malaysia: A Case Series.
Cureus
August 2024
Ophthalmology and Oculoplastic Surgery, KPJ Klang Specialist Hospital, Klang, MYS.
Article Synopsis
- - Parinaud oculoglandular syndrome (POGS) is a rare condition characterized by one-sided eye inflammation and lymph node swelling, often linked to cat scratch disease (CSD) caused by Bartonella henselae (BH).
- - Diagnosing POGS can be difficult due to its rarity and the wide range of potential causes, with the best diagnostic method being the PCR DNA test for BH, which isn't always readily available.
- - A series of three cases demonstrated effective management with antibiotics and non-drug measures like flea control, stressing the need for increased awareness among clinicians regarding CSD, especially in patients with feline exposure, and calling for more research to improve diagnosis and treatment options.
Multifocal Osteomyelitis in an Adolescent Patient With Cat Scratch Disease.
Case Rep Infect Dis
September 2024
Division of Pediatric Infectious Disease Ataşehir Memorial Hospital, İstanbul, Türkiye.
Article Synopsis
- A 15-year-old girl with a history of a cat scratch developed severe back pain and was found to have multifocal vertebral osteomyelitis following her initial lymphadenopathy diagnosis.
- Diagnosis of osteomyelitis secondary to CSD involved MRI, biopsy, PET/CT, and blood tests, highlighting the need to consider CSD in cases of severe musculoskeletal pain. *
Cat-Scratch Disease Mimicking Neoplastic Etiology in a Complex Clinical Presentation: A Case Report.
Cureus
August 2024
Internal Medicine, University of Kentucky College of Medicine, Lexington, USA.
Article Synopsis
- Cat-scratch disease (CSD) is often caused by a cat scratch or bite, leading to swollen lymph nodes and symptoms like fever and muscle pain.
- A case study details a 50-year-old man with multiple health issues, including HIV and Crohn's disease, who developed severe lymphadenopathy, initially misdiagnosed as cancer before being identified as CSD.
- The patient responded well to doxycycline treatment, highlighting the need for healthcare providers to consider CSD as a potential diagnosis for lymph node enlargement, especially in HIV patients, despite their immune status.
Cat Scratch Disease in Pediatrics: Who Has Systemic Involvement?
Pediatr Infect Dis J
January 2025
From the Pediatric Infectology Service, Children's Hospital Dr. Ricardo Gutiérrez, Hospital associated with the Faculty of Medicine of the University of Buenos Aires.
Article Synopsis
- Bartonella henselae is the bacteria behind cat scratch disease (CSD), which usually causes swollen lymph nodes but can sometimes lead to serious complications; this study aimed to analyze differences in clinical features between systemic and localized cases in children.
- The study reviewed medical records from a pediatric hospital in Buenos Aires, identifying 197 CSD patients, predominantly aged 8 years, with common symptoms being fever and lymphadenopathy; systemic involvement occurred in 34.5% of cases, often presenting as abscesses in organs like the spleen and liver.
- Findings indicated that patients with systemic diseases exhibited higher rates of fever and elevated C-reactive protein levels; nearly all patients received antibiotic
Three-Month History of Lymphadenopathy Caused by Bartonella henselae in a 13-Year-Old Following a Dog Scratch.
Cureus
August 2024
Family Medicine, Greenbrier Valley Medical Center, Ronceverte, USA.
Article Synopsis
- A 13-year-old healthy boy presented with a persistent right neck mass, fatigue, and weight loss, raising concerns about potential cancer.
- After initial tests showed no abnormalities, he returned with new symptoms like swallowing difficulties and throat pain, and the neck mass had changed appearance.
- Blood tests indicated infection, leading to a diagnosis of lymphoid proliferation and treatment with antibiotics, resulting in significant symptom improvement and near resolution of the mass.
Cat scratch colon in a patient with very early-onset Crohn's disease with diverting ileostomy.
J Pediatr Gastroenterol Nutr
November 2024
Department of Pediatric Gastroenterology, Hepatology, and Nutrition, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas, USA.
Neuroretinitis with Initial Seronegativity and an Absent Macular Star: A Case Report and Literature Review.
Trop Med Infect Dis
August 2024
Department of Ophthalmology, National University Hospital, 1E Kent Ridge Rd, Singapore 119228, Singapore.
Article Synopsis
- *A case of neuroretinitis was reported where the typical sign (macular star) was absent at first, leading to initial misdiagnosis; however, the connection to a cat scratch was later confirmed.
- *The case highlights the importance of thorough medical evaluation and follow-up tests for diagnosing neuroretinitis to avoid misdiagnosis in patients experiencing sudden vision loss.
Atypical Haemorrhagic Presentation of Neuro-Retinitis and Serous Retinal Detachment Secondary to Cat-Scratch Disease.
Neuroophthalmology
March 2024
Department of Ophthalmology, Baylor College of Medicine, Houston, Texas, USA.
Article Synopsis
- Cat-scratch disease (CSD) is caused by a specific type of bacteria and can lead to various symptoms, including rare cases of neuroretinitis, which affects vision.
- A 14-year-old girl experienced sudden vision loss after being scratched by cats, prompting her to seek emergency care, where doctors found significant swelling of the optic disc and other eye issues.
- The patient was treated with antibiotics and steroids, resulting in improved vision and resolution of her eye problems after completing the treatment.
Cat Scratch Disease Presenting with Right Branch Retinal Artery Occlusion and Left Neuroretinitis.
Case Rep Ophthalmol
August 2024
Kensington Vision and Research Centre, Toronto, ON, Canada.
Article Synopsis
- A 42-year-old man experienced vision loss in one eye after flu-like symptoms and contact with a stray kitten, leading to a diagnosis related to cat scratch disease (CSD).
- Clinical tests revealed branch retinal artery occlusion in one eye and neuroretinitis in the other, showcasing the unusual ocular complications associated with CSD.
- This case highlights the need for awareness of CSD as a potential cause of eye conditions in patients with recent cat exposure and related symptoms, emphasizing the diversity of its ocular manifestations.
Hepatic Abscesses and Associated Osteomyelitis in a Pediatric Patient.
Case Rep Infect Dis
August 2024
Division of Pediatric Infectious Disease University of Nebraska Medical Center, Omaha, NE, USA.
Article Synopsis
- Cat scratch disease is caused by a Gram-negative bacillus from cat saliva or scratches, presenting primarily as localized swelling or regional lymph nodes.
- Rare complications can occur, including serious issues affecting the liver and bones, such as hepatic abscesses and osteomyelitis, especially in children with a history of cat exposure.
- A 2-year-old boy with a severe case was treated successfully with azithromycin and rifampin after showing symptoms like fever and musculoskeletal pain, highlighting the importance of abdominal imaging in diagnostics for this condition.
Sequence typing of Bartonella henselae in small Indian mongooses (Urva auropunctata).
Sci Rep
August 2024
Intracellular Pathogens Research Laboratory, Department of Clinical Sciences, College of Veterinary Medicine, Comparative Medicine Institute, North Carolina State University, Raleigh, NC, USA.
This study aimed to determine the sequence type (ST) of Bartonella henselae infecting small Indian mongooses from Saint Kitts via multi-locus sequence typing (MLST). This investigation used stored EDTA blood (n = 22) samples from mongooses previously identified as positive for B. henselae.
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