Pulpotomy in primary teeth: Biodentine™ versus calcium hydroxide. A systematic review and meta-analysis.

Introduction: Pulpotomy is the total amputation of coronal pulp tissue and subsequent placement of a pulpotomy agent over the root canal orifices, followed by a coronal seal. The most suitable pulpotomy agent for successful treatment outcomes remains controversial.

Objectives: To evaluate and compare the clinical and radiographic success of calcium hydroxide (CH) and Biodentine (BD) in primary tooth pulpotomy at 6 and 12 months.

Sacituzumab Govitecan in Triple Negative Breast Cancer: A Systematic Review of Clinical Trials.

Background/objectives: Triple-negative breast cancer is difficult to treat due to the absence of hormone receptors and Her2neu. Sacituzumab govitecan is a new therapeutic approach that uses an antibody directed against the Trop-2 antigen present in solid epithelial tumors, linked to the active metabolite SN-38, similar to irinotecan, to specifically target cancer cells while minimizing damage to healthy cells. The objective of the present review was to evaluate the efficacy and safety of sacituzumab govitecan as a single treatment in patients with triple-negative breast cancer and to compare its results with the standard conventional chemotherapy regimen currently used in this disease.

Synergistic Integration of α-AgWO into PLA/PBAT for the Development of Electrospun Membranes: Advancing Structural Integrity and Antimicrobial Efficacy.

The rising resistance of various pathogens and the demand for materials that prevent infections drive the need to develop broad-spectrum antimicrobial membranes capable of combating a range of microorganisms, thereby enhancing safety in biomedical and industrial applications. Herein, we introduce a simple and efficient technique to engineer membranes composed of polylactic acid (PLA) and polybutylene adipate terephthalate (PBAT) biopolymers and α-AgWO particles using an electrospinning technique. The corresponding structural, thermal, mechanical, and antimicrobial properties were characterized.

The effects of three types of balance training programs on measures of balance and muscle power in prepubertal children: A randomized controlled trial.

Objectives: The purpose of this study was to investigate the effects of static (SBT), quasi-dynamic (QDBT), and dynamic (DBT) balance training on balance and muscle power performance in prepubertal children.

Design: Randomized, controlled trial design.

Methods: Fifty-six children (10 and 11 years) were randomly assigned to static (n = 14), quasi-dynamic (n = 14) and dynamic balance training (n = 15), or a control group (n = 13).

Animal welfare of Lacaune lambs weaned from artificial feeding.

Introduction: Nowadays, many dairy sheep farms opt for milk replacers after birth. Weaning lambs from milk replacers is expected to be a stressful situation.

Methods: With the aim of researching this practice on the animal behavior, body weight yields, and sanitary status of Lacaune lambs, 60 healthy animals from the same lambing house were employed.

MAKO robot-assisted total hip arthroplasty: a comprehensive meta-analysis of efficacy and safety outcomes.

Background: Introduction: Robotic surgery in total hip arthroplasty (THA) has emerged as a promising approach for improving precision and reducing errors. This meta-analysis aimed to compare the efficacy and safety of robot-assisted MAKO total hip arthroplasty.

Methods: Studies were searched using four databases.

Benefits of a light- intensity bout of exercise on attentional networks functioning.

The effects of physical exercise on attentional performance have received considerable interest in recent years. Most of previous studies that assessed the effect of an acute bout of exercise on attentional performance have generally been approached by analysing single attentional functions in isolation, thus ignoring the functioning of other attentional functions, which characterizes the real perception-action environmental conditions. Here, we investigated the effect of two different intensities (light vs.

Surgical Precision of MICA and Reverdin-Isham Using 3D-Printed Guides: A Cadaveric Study.

: Hallux valgus is a common foot deformity that requires surgical correction to restore proper alignment. Precision in the osteotomies performed during these surgeries is critical to avoid complications and improve outcomes. However, variability in surgeon experience can negatively affect precision.

Therapeutic and Immunologic Effects of Short-Chain Fatty Acids in Inflammatory Bowel Disease: A Systematic Review.

Inflammatory bowel disease is a chronic condition characterized by recurrent intestinal inflammation. Its etiopathogenesis is driven by a series of events that disrupt the mucosal barrier, alter the healthy balance of intestinal microbiota, and abnormally stimulate intestinal immune responses. Therefore, numerous studies suggest the use of short-chain fatty acids and their immunomodulatory effects as a therapeutic approach in this disease.

Adaptation and Validation of the Nursing Attitude Questionnaire in a Spanish Population.

Background: Nursing, as an essential component of contemporary healthcare systems, has undergone significant changes in recent decades, resulting in an increase in research across various fields, such as mental health, well-being, and the development of the discipline itself. Currently, gender stereotypes persist, impacting the social image of the profession and influencing the professional identity of nurses and consequently, their work performance and the quality of care provided. Both public and internal perceptions of the profession are critical factors in these dynamics.

Possible Health Benefits and Risks of DeepFake Videos: A Qualitative Study in Nursing Students.

Background: "DeepFakes" are synthetic performances created by AI, using neural networks to exchange faces in images and modify voices.

Objective: Due to the novelty and limited literature on its risks/benefits, this paper aims to determine how young nursing students perceive DeepFake technology, its ethical implications, and its potential benefits in nursing.

Methods: This qualitative study used thematic content analysis (the Braun and Clarke method) with videos recorded by 50 third-year nursing students, who answered three questions about DeepFake technology.

Tactical analysis of direct attack from the English Premier League and Spanish La Liga.

The aim of this study was to evaluate the effect of tactical and contextual dimensions on the offensive performance, in terms of degree of penetration or creation of goal scoring opportunities (GSO), of direct attacks in the English Premier League (EPL) and Spanish La Liga. In total, 10,078 team possessions from 40 random La Liga and EPL matches were initially selected. From that, 2,384 possessions categorized as open play direct attacks were selected for analysis, including a first univariate binary regression analysis and a further construction of adjusted binary multivariate logistic regression models.

Clinical and Sociodemographic Factors Related to Amyotrophic Lateral Sclerosis in Spain: A Pilot Study.

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of unknow etiology. Male sex is a well stablished risk factor, but other factors such as early and adult life expositions show contradictory evidence. Aim: to explore the link of clinical, sociodemographic, and occupational factors with ALS patients in Spain and the impact of these factors in functionality.

Amplitude of Lower Limb Muscle Activation in Different Phases of the Illinois Test in Parkinson's Disease Patients: A Pilot Study.

Parkinson's disease (PD) is a neurodegenerative disorder with high prevalence in men and is characterized by symptoms such as tremors and gait difficulties. This study aimed to determine muscle activation in patients with PD by considering sex differences. This pilot study used analytical, quantitative, observational, and case-control methods.

Cadaveric study of the ultrasound-guided inter-transversospinalis plane block in dogs for the cervical epaxial musculature region.

Blockage of the dorsal rami of the spinal nerves (DRSN) provides analgesia to the epaxial musculature area in dogs. However, techniques to block the DRSN at the cervical level in dogs haven't yet been investigated. This study aimed to study the anatomy of the cervical area, and to describe a new ultrasound (US)-guided inter-transversospinalis plane (ITP) block technique at the 5th cervical vertebrae (C5).