6 results match your criteria: "Catholic University Gemelli Hospital[Affiliation]"
Stimulating TSH receptor autoantibodies immunoassay: analytical evaluation and clinical performance in Graves' disease.
Ann Clin Biochem
January 2018
1 Department of Laboratory Medicine, Catholic University-Gemelli Hospital, Rome, Italy.
Background Thyroid-stimulating hormone (TSH) receptor (TSHR) autoantibodies (TRAbs) are a heterogeneous group of antibodies (Abs) with different functionalities. Among all TRAbs, only the stimulating ones (S-TRAbs) are considered as the pathogenetic marker of Graves' disease (GD). To date, the methods available for TRAbs testing are based on immunoassays (IMAs) which detect total serum TRAbs or bioassays which are not suitable in clinical practice, even though they discern Abs functionality.
View Article and Find Full Text PDFPrevalence and characteristics of serrated lesions of the colorectum in Italy: A multicentre prospective cohort study.
Dig Liver Dis
June 2015
Gastroenterology Unit, Hospital Curto, ASL SAPolla, Italy.
Article Synopsis
- This study examined the prevalence and predictors of serrated lesions, significant precursors to colorectal cancer, among a sample of patients in Italy during colonoscopy over several months.* -
- Out of nearly 2,500 colonoscopies conducted, 173 serrated lesions were found, making up 7% of the total, with a notable occurrence in the left colon and among serrated adenomas in the proximal colon.* -
- Key predictors for identifying these lesions included younger patient age, right-sided colon location, non-polypoid shapes, and smaller lesion sizes, while no specific predictors were found for serrated adenomas.*
Methane intestinal production and poor metabolic control in type I diabetes complicated by autonomic neuropathy.
Minerva Endocrinol
September 2014
Gastroenterology and Internal Medicine Catholic University, Gemelli Hospital, Rome, Italy2Diabetology Unit, Catholic University Gemelli Hospital, Rome, Italy -
Aim: At the state of art it's unknown the correlation between diabetes and lower gastrointestinal disorders. Some studies show a significantly higher prevalence of small intestinal bacterial overgrowth in patients with type I diabetes in particular complicated by autonomic neuropathy. No data exists about gastrointestinal methane production in patients with diabetes and autonomic diabetic neuropathy.
View Article and Find Full Text PDFSaccharomyces cerevisiae-associated diarrhea in an immunocompetent patient with ulcerative colitis.
J Clin Gastroenterol
January 2003
Department of Internal Medicine, Catholic University Gemelli Hospital, Rome, Italy.
Infectious diarrhea is common in cases of ulcerative colitis (UC), caused by resistance to treatment. In particular, it has been associated with cytomegalovirus or infection has rarely been observed in human beings, but has never been seen in immunocompetent patients. We report a case of intestinal infection presenting as acute diarrhea in a patient with a 10-year history of UC who was never treated with immunosuppressants.
View Article and Find Full Text PDFImproved survival and local control after intraoperative radiation therapy and postoperative radiotherapy: a multivariate analysis of 46 patients undergoing surgery for pancreatic head cancer.
Arch Surg
March 2001
Department of Digestive Surgery, Istituto Clinica Chirurgica, Catholic University-Gemelli Hospital, L.go A. Gemelli, 8, 00168 Roma, Italy.
Hypothesis: Despite aggressive approaches, locoregional tumor control and survival rates for patients with cancer of the pancreatic head remain disappointing. In the present study, we address whether intraoperative and adjuvant radiotherapy may improve the prognosis for these patients.
Design: A retrospective study.