4,217 results match your criteria: "Catatonia"

Catatonia-asossicated urinary retention in geriatric patients: a case series report.

BMC Geriatr

December 2024

Faculty of Medicine, Department of Geriatric Psychiatry, University of Ottawa, Ottawa, ON, Canada.

Background: Catatonia is an underdiagnosed neuropsychiatric condition, with only a few studies focusing on medical sequalae among elderly populations. Delayed treatment results in complications with high morbidity and mortality. Among elderly individuals, one such complication is urinary retention.

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Background: Creatine kinase (CK) is an intracellular enzyme expressed most commonly in tissues such as skeletal muscle. CK can be used as an investigation to support the diagnosis of conditions such as neuroleptic malignant syndrome (NMS), a rare idiosyncratic drug reaction - classically to antipsychotic medications - which can be fatal. Routine screening of CK in psychiatric inpatients is a known practice, but its value is uncertain.

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Catatonia is a serious neuropsychiatric syndrome of motor and behavioral dysfunction where electroconvulsive therapy (ECT) is a well-proven treatment modality. ECT is also preferred as it is a low-risk procedure compared to chronic medications having significant side effects. However, the cardiovascular events that occur during ECT are a major cause of morbidity and mortality in patients with an abnormal cardiovascular pathophysiology.

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The differential diagnosis of neurocognitive and psychiatric disorders, particularly when symptoms overlap significantly, poses a substantial challenge in clinical practice. Parkinson's disease (PD), Lewy body dementia, and catatonia are distinct conditions that can present with similar motor and cognitive symptoms, complicating accurate diagnosis and effective treatment. We report the case of a 45-year-old male patient who presented for electroconvulsive therapy (ECT) evaluation.

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Catatonia is a complex neuropsychiatric syndrome characterised by abnormal psychomotor disturbance, which poses a diagnostic and treatment challenge to clinicians. It is a life-threatening condition in its severe form, termed malignant and characterised by hyperthermia and autonomic disturbances. Early recognition and treatment are important in its management.

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Palliative Electroconvulsive Therapy: A Descriptive Cohort Study.

J Acad Consult Liaison Psychiatry

December 2024

Department of Medicine, Duke University School of Medicine, Durham, NC; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC.

Introduction: Palliative care (PC) is the standard of care for patients with serious medical illnesses, or those conditions associated with high risk of mortality and negative impact on quality of life (QOL). Electroconvulsive therapy (ECT) is the gold standard treatment for certain psychiatric conditions, which may co-occur with serious medical illnesses. However, the use of "palliative ECT" (PECT) in this context is understudied.

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Introduction: Catatonia is a neuropsychiatric disorder marked by significant disturbances in motor, cognitive, and affective functioning and that is frequently under-diagnosed. To enhance clinical detection of catatonia, this study aimed to develop a rapid, sensitive Catatonia Quick Screen (CQS) using a reduced set of catatonic signs to facilitate screening in adult and pediatric patients.

Methods: Data were derived from two retrospective cohorts totaling 446 patients (254 adults, 192 children) who screened positive for catatonia using the Bush Francis Catatonia Screening Instrument (BFCSI).

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Article Synopsis
  • An adolescent with ANMDAE and catatonia was treated with zolpidem after traditional treatments like benzodiazepines and ECT failed.
  • ANMDAE presents with neuropsychiatric symptoms, including memory issues, seizures, and catatonia, which can lead to serious medical complications.
  • Current guidelines offer limited options for treating catatonia in young patients who don't respond to standard treatments, and zolpidem may be a viable alternative.
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Catatonia After Low-Dose Haloperidol During Thyroid Storm: A Case Report and Systematic Review of Published Cases.

J Acad Consult Liaison Psychiatry

November 2024

Inova Behavioral Health Services, Inova Fairfax Medical Campus, Falls Church, VA.

Article Synopsis
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This is a case report of a previously healthy 26-year-old female with unexplained neurological symptoms that eventually developed malignant catatonia. Because malignant catatonia has a range of clinical manifestations, making prompt diagnosis a challenging task. Due to her relapsing symptoms, the patient was admitted to the inpatient psychiatric unit three times in less than 2 months, and eventually recovered with high doses of lorazepam and several electroconvulsive therapy (ECT) treatments after a stay in the intensive care unit (ICU).

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  • - Niemann-Pick Type-C (NPC) disease can lead to serious neuropsychiatric issues, including catatonia, which doesn't always respond well to standard treatments like antipsychotics.
  • - A patient with adult-type NPC developed catatonia that persisted despite various medications, but improved significantly with electroconvulsive therapy (ECT).
  • - Combining ECT with lorazepam managed the catatonia, and adding lamotrigine led to full remission for eight months, suggesting lamotrigine's potential benefits in treating recurrent catatonia.
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  • - Cerebral brain abscesses are rare but serious, especially in immunocompromised people, and can often imitate psychiatric disorders, complicating their diagnosis.
  • - A case study involves a 47-year-old HIV-positive woman with a psychiatric history who showed unusual symptoms like catatonia, leading to a diagnosis of a large brain abscess after imaging revealed significant issues.
  • - The patient received immediate treatment, including surgery, and showed improvement, highlighting the need for thorough diagnostic procedures and multidisciplinary care in similar cases to ensure better health outcomes.
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  • The article details a case of a teenage girl diagnosed with juvenile parkinsonism caused by genetic mutations, showcasing the challenges in diagnosing and treating this condition alongside other psychiatric disorders.
  • Despite years of psychiatric evaluations and treatments, clear symptoms of parkinsonism only emerged later, complicating the diagnosis.
  • It emphasizes the need for a collaborative approach between psychiatrists and neurologists for accurate diagnosis and effective treatment in cases with overlapping symptoms.
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The effectiveness of repetitive transcranial magnetic stimulation (rTMS) in patients with catatonia associated with another mental disorder: A systematic review.

Asian J Psychiatr

November 2024

Department of Psychiatry, University of Saskatchewan, Royal University Hospital, Ellis Hall,  103 Hospital Drive, Saskatoon, SK S7N 0W8, Canada. Electronic address:

Background: Catatonia is a rare but life-threatening condition characterized by a constellation of psychomotor disturbances. The most widely used treatments of catatonia include benzodiazepines and electroconvulsive therapy. Despite the widespread use of benzodiazepines and the high response rate of catatonia to ECT, there are instances where catatonia does not respond to first-line treatments.

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Article Synopsis
  • SHANK1 is a gene that produces a protein involved in the structure and function of excitatory synapses, part of a family that includes SHANK2 and SHANK3.
  • An 11-year-old boy with developmental delays and no family psychiatric history developed catatonia, with imaging and autoimmune tests showing no abnormalities.
  • Genetic testing identified a new, likely harmful SHANK1 variant, marking the first documented case of catatonia linked to a SHANK1 mutation, although similar symptoms have been associated with SHANK3 issues.
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Background: Managing psychiatric emergencies during pregnancy is often challenging, as the safety of both the mother and the unborn fetus needs to be considered. This study aimed to examine the nature of psychiatric emergencies in pregnancy, their management, and clinical outcomes in women presenting to a psychiatry emergency room (ER).

Methods: Charts of perinatal women consulting psychiatry ER between January 2016 and June 2021 were reviewed for the nature of the psychiatric emergency, pregnancy details, psychiatric symptoms, sociodemographic information, medical comorbidities, clinical diagnosis, and care plan.

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Phelan-McDermid syndrome-associated psychosis: a systematic review.

Acta Neuropsychiatr

November 2024

Department of Psychiatry, Hotchkiss Brain Institute, Mathison Centre for Mental Health Research and Education, University of Calgary, Calgary, AB, Canada.

Objective: Phelan-McDermid syndrome is a rare genetic disorder characterised by various neurodevelopmental, medical, and psychiatric issues. Although bipolar disorder-like presentations and catatonia are particularly common, psychosis has also been reported but is less well described. As such, this systematic review sought to characterise the phenomenology of psychosis in Phelan-McDermid syndrome, clarify the association of psychotic symptoms with other neuropsychiatric features of the disorder, and describe antipsychotic treatment response.

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