475 results match your criteria: "Carotid Sinus Hypersensitivity"

Article Synopsis
  • Medical advances have enhanced our understanding of the autonomic nervous system's involvement in various cardiac conditions, including syncope and bradycardia, which, while not usually fatal, can lead to significant symptoms and complicated treatments.
  • Recent interest focuses on cardioneuroablation, a technique that directly targets the parasympathetic nervous system to improve management of these conditions alongside traditional treatments like lifestyle changes and medications.
  • The review discusses the principles and emerging evidence supporting cardioneuroablation for conditions like vasovagal syncope and atrioventricular block, emphasizing the importance of ongoing clinical studies for assessing long-term effectiveness and safety.
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Article Synopsis
  • - Syncope is a common issue in emergency departments and can be caused by various factors, with carotid sinus hypersensitivity (CSS) being a significant one affecting quality of life.
  • - A 43-year-old man with recurrent syncope was diagnosed with CSS after thorough evaluation and treated with a stellate ganglion block over 12 days.
  • - Post-treatment, the patient showed symptom improvement and remained symptom-free during a 7-month follow-up, suggesting the need for more research on stellate ganglion block therapy as a potential treatment for CSS.
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Article Synopsis
  • * The patient's laryngeal cancer caused lymphedema that compressed the carotid arteries, leading to symptoms like hypotension and bradycardia, which were managed with atropine and a pacemaker, although he eventually continued treatment with non-invasive theophylline.
  • * The report highlights the rarity of CSS in head and neck malignancies and stresses the need for further research to improve understanding and treatment options for managing CSS in these patients, as current evidence is limited.
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Article Synopsis
  • - A 60-year-old male with tonsillar squamous cell carcinoma experienced serious heart issues (bradycardia and hypotension) after dental surgery, linked to carotid sinus syndrome (CSS).
  • - His symptoms worsened, resulting in the need for a pacemaker, as imaging revealed a large neck mass and lymph node problems indicating CSS caused by tumor pressure.
  • - This case emphasizes the importance of recognizing CSS in patients with head and neck cancers, especially when they show signs of low blood pressure and slow heart rate when changing positions.
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The effect of carotid sinus neurectomy for carotid restenosis: a study protocol for a double-blinded and randomized controlled trial.

Trials

January 2024

Department of Neurosurgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.

Background: Patients undergoing carotid endarterectomy (CEA) have a high restenosis rate, which increases the risk of stroke, and there is still a lack of effective treatment for restenosis. The cause of stenosis is related to local inflammatory reactions. Some basic studies have shown that the inflammatory response causing arterial stenosis is closely related to the nerve axons distributed in its outer membrane, and that removal of the nerve is effective in reducing the inflammatory response to prevent arterial stenosis.

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Cardiovascular Disorders and Falls Among Older Adults: A Systematic Review and Meta-Analysis.

J Gerontol A Biol Sci Med Sci

February 2024

Department of Medical Gerontology, School of Medicine, Trinity College Dublin, Dublin, Ireland.

Article Synopsis
  • Falls are a major health risk for older adults, often linked with serious injuries and hospitalizations, and cardiovascular disorders are recognized as key contributing factors.
  • This systematic review analyzed studies on adults aged 50 and older to evaluate how various cardiovascular conditions relate to fall risks.
  • Findings revealed significant associations between several cardiovascular disorders (like stroke and atrial fibrillation) and falls, highlighting the importance of cardiovascular evaluations in fall prevention strategies.
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Article Synopsis
  • - A 63-year-old patient with sarcoidosis developed severe nosebleeds and a stroke while on long-term metipred therapy; CT scans showed significant issues in the sphenoid bone and left optic nerve.
  • - Angiography revealed a blockage in the left internal carotid artery, leading to surgical thrombus removal, during which the patient experienced major nasal bleeding.
  • - Although the bleeding was controlled through embolization of the artery, the patient ultimately died from acute posthemorrhagic anemia, with an autopsy confirming a mycotic aneurysm as the cause of the complications.
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Article Synopsis
  • * The study indicates that NMS may represent two distinct clinical types: one beginning in youth, often benign, and another starting in old age, which may be linked to pathological autonomic nervous system issues.
  • * Future research should differentiate between these two types, particularly focusing on the prognosis of NMS in older adults, as its current implications for severe health outcomes are still not well understood.
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Article Synopsis
  • - Carotid body tumor surgeries can lead to complications, but instances of intraoperative cardiac arrest are extremely rare, with only about 10 cases reported.
  • - In a recent case, a 58-year-old woman experienced cardiac arrest during surgery for bilateral carotid body tumors due to carotid sinus hypersensitivity; she recovered successfully after prompt intervention.
  • - The rarity of such cardiac events highlights the importance of recognizing potential risks beforehand; using a temporary pacemaker may be advisable for patients showing signs of carotid sinus hypersensitivity before surgery.
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Article Synopsis
  • - A 43-year-old man experienced fainting episodes, which were linked to emotional stress and pain, leading to a diagnosis of vasovagal syncope (VVS) and carotid sinus hypersensitivity after various tests showed no underlying heart or neurological issues.
  • - His treatment involved modified tilt training exercises at home, which helped eliminate future syncopal episodes and demonstrated the effectiveness of patient education and self-management.
  • - The case suggests a connection between the carotid sinus and the neural mechanisms responsible for VVS, highlighting the need for accurate diagnoses of syncopal conditions.
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Article Synopsis
  • Over the past 50 years, views on falls in older adults have shifted from acceptance as a normal part of aging to recognizing that falls can be prevented through various strategies.
  • Effective fall prevention methods include exercise, particularly balance training, as well as interventions like improved podiatry, home safety modifications, cataract surgery, and vitamin D supplementation.
  • Recent technological advancements offer promising low-cost solutions for fall prevention, but more work is needed to broaden access and adherence to these interventions while maintaining their effectiveness.
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Article Synopsis
  • Carotid sinus hypersensitivity can cause unexplained fainting (syncope) in older adults, with varying symptoms.
  • A 56-year-old man with coronary artery disease experienced syncope and was ultimately diagnosed with carotid sinus hypersensitivity, leading to the placement of a dual chamber pacemaker for treatment.
  • Despite having other health issues, like coronary artery disease, clinicians should still consider carotid sinus hypersensitivity as a potential cause of syncope.
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Article Synopsis
  • * A 66-year-old man with a notable medical history presented symptoms like facial swelling and breathing difficulties, leading to the identification of his FM alongside superior vena cava syndrome through CT imaging.
  • * Treatment with corticosteroids and diuretics provided limited relief, but the patient’s condition worsened, highlighting the challenges in managing FM and the need for accurate diagnostic techniques to differentiate it from malignancies.
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Article Synopsis
  • The study investigates how syncope (temporary loss of consciousness) and presyncope affect quality of life (QoL) in patients, noting a significant impact across various QoL domains.
  • A systematic literature review found that out of 12,258 records, only 36 studies highlighted the negative effects of conditions like vasovagal syncope (VVS) and postural orthostatic tachycardia syndrome (POTS) on QoL, using 12 different measurement tools.
  • Key findings indicate that patients with more frequent syncopal events and additional health issues experience lower QoL scores, emphasizing the need for further research to alleviate the burden of these conditions.
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Article Synopsis
  • Deglutition syncope and carotid sinus hypersensitivity are reflexes that can cause serious heart issues due to neural responses.
  • These conditions are often linked to problems in the gastrointestinal or cardiovascular systems, but they can occur without these underlying causes.
  • This text presents the first documented case where deglutition syncope occurred alongside acute suppurative parotitis, which improved after treating the swelling of the parotid gland.
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Recurrent syncope from parapharyngeal cancer.

BMJ Support Palliat Care

December 2023

Palliative Care, Saint Francis Hospice, Romford, UK

Article Synopsis
  • The glossopharyngeal nerve can lead to reflex bradycardia and syncope in patients with head and neck cancer, although such cases are rare.
  • The common assumption that these symptoms stem from carotid sinus hypersensitivity is often incorrect, as parapharyngeal lesions affecting the glossopharyngeal nerve may also play a significant role.
  • In reported cases, symptomatic treatment options were limited due to the patients' frailty, but both patients showed some improvement in their syncopal symptoms with anticholinergic medications.
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Article Synopsis
  • A 73-year-old man developed frequent, time-specific syncopal episodes (loss of consciousness) after undergoing surgery for recurrent hypopharyngeal cancer, which were linked to the impact of his tumor on his autonomic nervous system.
  • *Diagnostic tests revealed complications from surgery, including an anastomotic stricture and carotid sinus syndrome, potentially triggered by swallowing and positional changes that affected blood flow.
  • *Treatment with disopyramide successfully reduced these syncopal episodes, and heart rate variability analysis indicated a shift from parasympathetic to sympathetic dominance in the morning hours, suggesting a link between autonomic tone and syncope.*
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Article Synopsis
  • * Before starting chemotherapy, tests revealed sinus arrest, indicating sick sinus syndrome (SSS), which was likely caused by the tumor's effect on her heart.
  • * Chemotherapy with R-CHOP was initiated successfully, and her sinus arrest improved, suggesting the tumor may have interfered with the carotid artery pressure receptors or stimulated the vagus nerve.
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Article Synopsis
  • - Dysautonomia is a collection of conditions that affect the autonomic nervous system, with various types including POTS, Chronic Fatigue Syndrome, Neurogenic Orthostatic Hypotension (nOH), and more; however, vasovagal syndromes, which are generally mild, are not covered in this article.
  • - Cardiovascular Autonomic Neuropathy (CAN) indicates a dysfunction in the cardiovascular autonomic nervous system, often linked to serious underlying conditions like diabetes and neurodegenerative diseases, and its presence typically leads to worse health outcomes.
  • - Orthostatic Hypotension (OH) is a significant indicator of dysautonomia severity, necessitating careful differentiation from other types of hypotension; managing medication in
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Article Synopsis
  • Carotid sinus syndrome (CSS) is a condition where neck movements or tight collars can cause severe drops in heart rate or blood pressure, potentially linked to tumors in the head and neck.
  • A case study of a 49-year-old woman with a neck mass showed her recurrent bradycardia episodes were triggered by head rotation, leading to the discovery of laryngocele through a CT scan.
  • Surgical treatment, specifically endolaryngeal carbon dioxide laser marsupialization, successfully resolved her bradycardia episodes, emphasizing the importance of considering laryngocele in CSS diagnoses.
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Article Synopsis
  • The text discusses postoperative complications following total thyroidectomy, particularly focusing on a rare case of sinus bradycardia in a 9-year-old boy with papillary thyroid carcinoma.
  • Post-surgery, the boy experienced vocal cord paresis and a chyle leak, along with asymptomatic sinus bradycardia that resolved on its own.
  • The study suggests that possible causes for the bradycardia include hypothyroidism, carotid sinus hypersensitivity, and damage to the cervical sympathetic ganglion, though these are not definitively proven in this single case.
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Reproducibility of carotid sinus massage.

Pacing Clin Electrophysiol

October 2020

Department of Cardiology, Arrhythmology Centre and Syncope Unit, Ospedali del Tigullio, Lavagna, Italy.

Article Synopsis
  • - The study aimed to evaluate the reproducibility of carotid sinus massage (CSM) using guidelines from the European Society of Cardiology, focusing on its effectiveness in diagnosing syncope.
  • - Among 109 patients who underwent a second CSM after 28 months, the reproducibility results indicated 78% for those with carotid sinus syndrome (CSS), 41% for carotid sinus hypersensitivity (CSH), and 77% for patients with negative results.
  • - The findings concluded that CSS has good reproducibility, while CSH does not, with about 50% of CSH patients showing a negative response on retesting, highlighting the overlap between these conditions.
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