276 results match your criteria: "Carlos III University[Affiliation]"

The main purpose of this work is to investigate and compare several deep learning enhanced techniques applied to X-ray and CT-scan medical images for the detection of COVID-19. In this paper, we used four powerful pre-trained CNN models, VGG16, DenseNet121, ResNet50,and ResNet152, for the COVID-19 CT-scan binary classification task. The proposed Fast.

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Gossip and competitive altruism support cooperation in a Public Good game.

Philos Trans R Soc Lond B Biol Sci

November 2021

Grupo Interdisciplinar de Sistemas Complejos (GISC), Department of Mathematics, Carlos III University of Madrid, Leganés, Spain.

When there is an opportunity to gain a positive reputation, individuals are more willing to sacrifice their immediate self-interest. Partner choice creates opportunities for competitive altruism, i.e.

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Do elections accelerate the COVID-19 pandemic?: Evidence from a natural experiment.

J Popul Econ

September 2021

University of Zurich, Department of Economics, Schönberggasse 1, 8001 Zurich, Switzerland.

Elections define representative democracies but also produce spikes in physical mobility if voters need to travel to polling places. In this paper, we examine whether large-scale, in-person elections propagate the spread of COVID-19. We exploit a natural experiment from the Czech Republic, which biannually renews mandates in one-third of Senate constituencies that rotate according to the 1995 election law.

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Background: Chagas disease (CD) is regarded as a possible risk for travellers to endemic areas of continental Latin America (LA). The aim of the study is to determine the risk of Trypanosoma cruzi (TC) infection among travellers to CD endemic areas and to identify risk factors for acquiring TC infection.

Methods/principal Finding: We designed a multicenter cross-sectional study among travellers in Spain (Badalona, Barcelona and Madrid).

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Fungal PJI is one of the most feared complications after arthroplasty. Although a rare finding, its high associated morbidity and mortality makes it an important object of study. The most frequent species causing fungal PJI is .

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Strongyloidiasis affects an estimated 600 million people worldwide, especially in tropical and subtropical areas. Single-dose ivermectin treatment has shown to be effective among immunocompetent patients with uncomplicated strongyloidiasis. Here, we present the protocol of the ImmunoStrong study, a prospective observational study aiming to evaluate the effectiveness and safety of a single-dose ivermectin for treatment of uncomplicated strongyloidiasis in immunosuppressed patients.

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Over the two last decades, coronaviruses have affected human life in different ways, especially in terms of health and economy. Due to the profound effects of novel coronaviruses, growing tides of research are emerging in various research fields. This paper employs a co-word analysis approach to map the intellectual structure of the coronavirus literature for a better understanding of how coronavirus research and the disease itself have developed during the target timeframe.

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This paper presents a methodological proposal based on the identification of highly cited papers (HCPs) at domestic-level in the Spanish Public University System (SUPE), in order to find the most outstanding publications in the local context. The principal aim is to detect different activity and impact profiles among Spanish universities and differentiate those institutions that play a more significant role. To determine which and how many are the highly cited papers at the domestic level (HCP-DL) collected in the Web of Science, three citation thresholds (1, 5, and 10%) were established.

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Dental radiography plays an important role in clinical diagnosis, treatment and making decisions. In recent years, efforts have been made on developing techniques to detect objects in images. The aim of this study was to detect the absence or presence of teeth using an effective convolutional neural network, which reduces calculation times and has success rates greater than 95%.

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Certain difficulties in path forecasting and filtering problems are based in the initial hypothesis of estimation and filtering techniques. Common hypotheses include that the system can be modeled as linear, Markovian, Gaussian, or all at one time. Although, in many cases, there are strategies to tackle problems with approaches that show very good results, the associated engineering process can become highly complex, requiring a great deal of time or even becoming unapproachable.

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Atrial fibrillation (AF) alters left atrial (LA) hemodynamics, which can lead to thrombosis in the left atrial appendage (LAA), systemic embolism and stroke. A personalized risk-stratification of AF patients for stroke would permit improved balancing of preventive anticoagulation therapies against bleeding risk. We investigated how LA anatomy and function impact LA and LAA hemodynamics, and explored whether patient-specific analysis by computational fluid dynamics (CFD) can predict the risk of LAA thrombosis.

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The activity of scientists promotes medical research in health services. However, on many occasions, these professionals do not know how to transfer their research results to the market. Therefore, it is worth providing data on aspects such as training in entrepreneurship and scientific mobility to foster knowledge transfer.

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The Role of Tenascin C in Cardiac Reverse Remodeling Following Banding-Debanding of the Ascending Aorta.

Int J Mol Sci

February 2021

Ludwig Boltzmann Institute for Cardiovascular Research at the Center for Biomedical Research, Medical University of Vienna, 1090 Vienna, Austria.

Background: Tenascin-C (TN-C) plays a maladaptive role in left ventricular (LV) hypertrophy following pressure overload. However, the role of TN-C in LV regression following mechanical unloading is unknown.

Methods: LV hypertrophy was induced by transverse aortic constriction for 10 weeks followed by debanding for 2 weeks in wild type (Wt) and TN-C knockout (TN-C KO) mice.

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Modifying SARS-CoV-2 vaccine schedule in Spain: When numbers matters.

Enferm Infecc Microbiol Clin (Engl Ed)

January 2021

Infanta Sofía University Hospital, Infectious Diseases Department, Universidad Europea de Madrid, Madrid, Spain.

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Correction of recessive dystrophic epidermolysis bullosa by homology-directed repair-mediated genome editing.

Mol Ther

June 2021

Centro de Investigación Biomédica en Red en Enfermedades Raras (CIBERER), Madrid, Spain; Fundación Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz, Madrid, Spain; Epithelial Biomedicine Division, Centro de Investigaciones Energéticas Medioambientales y Tecnológicas (CIEMAT), 28040 Madrid, Spain. Electronic address:

Genome-editing technologies that enable the introduction of precise changes in DNA sequences have the potential to lead to a new class of treatments for genetic diseases. Epidermolysis bullosa (EB) is a group of rare genetic disorders characterized by extreme skin fragility. The recessive dystrophic subtype of EB (RDEB), which has one of the most severe phenotypes, is caused by mutations in COL7A1.

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Background: The study aimed at exploring whether muscle membrane disruption, as a surrogate for muscle damage, and inflammation recovery following a mountain ultramarathon (MUM) was related with race performance and postrace physical activity.

Methods: Blood samples were obtained from thirty-four athletes (29 men and 5 women) before a 118-km MUM, immediately after and three- and seven-days postrace. Creatine kinase (CK), lactate dehydrogenase (LDH) and C-reactive protein (CRP) were compared between faster (FR) and slower (SR) runners.

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In this paper we describe the control approaches tested in the improved version of an existing soft robotic neck with two Degrees Of Freedom (DOF), able to achieve flexion, extension, and lateral bending movements similar to those of a human neck. The design is based on a cable-driven mechanism consisting of a spring acting as a cervical spine and three servomotor actuated tendons that let the neck to reach all desired postures. The prototype was manufactured using a 3D printer.

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Go to gate: COVID-19 imported cases in Madrid and the potential role of airport transmissions.

Trans R Soc Trop Med Hyg

July 2021

La Paz- Carlos III University Hospital-IdiPAZ, National Referral Unit for Imported Tropical Diseases, Tropical & Travel medicine Unit. Infectious Diseases Department, Paseo de la Castellana, 261 28046-Madrid, Spain.

Data on imported cases of COVID-19 are scarce. Recorded imported cases in Madrid, Spain represented 0.08% of the total cases from May to December 2020, as reported by the Epidemiology Service of Madrid Autonomous Community.

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The aim of the study was to describe the contamination in heater-cooler devices after the application of a protocol of cleaning and disinfection in a tertiary hospital. It was an observational study at the La Paz-Cantoblanco-Carlos III University Hospital, Madrid, Spain. Seven heater-cooler devices are used in our hospital: five 3T Sorin (LivaNova) and two Maquet.

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Fracture resistance of additive manufactured and milled implant-supported interim crowns.

J Prosthet Dent

February 2022

Associate Professor and Program Director of Graduate in Advanced Implant Prosthodontics, Department of Conservative Dentistry and Prosthodontics, School of Dentistry, Complutense University of Madrid, Madrid, Spain.

Statement Of Problem: Interim dental prostheses can be fabricated by using subtractive or additive manufacturing technologies. However, the fracture resistance of implant-supported interim crowns fabricated by using vat-polymerization additive manufacturing methods remains unclear.

Purpose: The purpose of this in vitro study was to evaluate the fracture resistance of anterior and posterior screw-retained implant-supported interim crowns fabricated by using subtractive and vat-polymerization direct light processing (DLP) additive manufacturing procedures.

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Novel insights in dimethyl carbonate-based extraction of polyhydroxybutyrate (PHB).

Biotechnol Biofuels

January 2021

Department of Science and Applied Technology (DISAT), Polytechnic University of Turin, Corso Duca degli Abruzzi 24, 10129, Turin, Italy.

Background: Plastic plays a crucial role in everyday life of human living, nevertheless it represents an undeniable source of land and water pollution. Polyhydroxybutyrate (PHB) is a bio-based and biodegradable polyester, which can be naturally produced by microorganisms capable of converting and accumulating carbon as intracellular granules. Hence, PHB-producing strains stand out as an alternative source to fossil-derived counterparts.

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Defective healing leading to cutaneous ulcer formation is one of the most feared complications of diabetes due to its consequences on patients' quality of life and on the healthcare system. A more in-depth analysis of the underlying molecular pathophysiology is required to develop effective healing-promoting therapies for those patients. Major architectural and functional differences with human epidermis limit extrapolation of results coming from rodents and other small mammal-healing models.

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