Distinct profiles of oxylipid mediators in liver, lung, and placenta after maternal nano-TiO nanoparticle inhalation exposure.

Nano-titanium dioxide (nano-TiO) is a widely used nanomaterial found in several industrial and consumer products, including surface coatings, paints, sunscreens and cosmetics, among others. Studies have linked gestational exposure to nano-TiO with negative maternal and fetal health outcomes. For example, maternal pulmonary exposure to nano-TiO during gestation has been associated not only with maternal, but also fetal microvascular dysfunction in a rat model.