92 results match your criteria: "Carilion Clinic Institute for Orthopaedics & Neurosciences[Affiliation]"

Modifications to the Geriatric Nutritional Risk Index Predicts Complications after Total Joint Arthroplasty.

J Arthroplasty

January 2025

Virginia Tech Carilion School of Medicine, 2 Riverside Circle, Roanoke, Virginia, 24016, United States of America; Department of Orthopaedic Surgery, Carilion Clinic Institute for Orthopaedics & Neurosciences, 2331 Franklin Road Southwest, Roanoke, Virginia, 24014, United States of America.

Background: Preoperative malnutrition is a known risk factor for postoperative complications following total joint arthroplasty (TJA), however, there is scant literature comparing which nutritional index is best at predicting these outcomes. The purpose of this study was to investigate the utility of the Maastricht Index (MI), Onodera's Prognostic Index (OPNI), the Geriatric Nutritional Risk Index (GNRI), and a novel, modified Geriatric Nutritional Risk Index (mGNRI) in predicting periprosthetic joint infection (PJI), wound complications (WC), readmission, and reoperation rates after TJA.

Methods: A single-center, retrospective cohort study was performed of patients who underwent primary TJA from January 2016 to December 2021.

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Preoperative Physical Therapy Is Protective From Construct Failure in Anterior Cruciate Ligament Reconstruction.

Sports Health

December 2024

Musculoskeletal Education and Research Center, Department of Orthopaedic Surgery, Institute for Orthopaedics and Neurosciences, Carilion Clinic, Roanoke, Virginia.

Background: Risk factors for anterior cruciate ligament reconstruction (ACLR) construct failure have been studied extensively. However, while some studies account for variables such as activity level, construct types, preoperative physical therapy, or patient demographics individually, comprehensive studies that control for all these factors simultaneously are scarce.

Hypothesis: By utilizing a robust multivariable analysis, the factors associated with an increased risk of ACLR construct failure can be determined.

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Article Synopsis
  • Intercellular mitochondrial transfer from mesenchymal stromal cells (MSCs) to chondrocytes may enhance tissue healing and has potential for treating osteoarthritis, but the mechanisms are not fully understood.
  • The study aimed to investigate the role of connexin 43 (Cx43) in this transfer, especially under oxidative stress conditions, and tested hypotheses about increased mitochondrial transfer and the influence of Cx43 expression.
  • Results indicated that oxidative stress in chondrocytes promoted mitochondrial transfer from MSCs, which was significantly enhanced by direct cell contact, with evidence showing Cx43 localizing at these contact sites.
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Obesity is an independent risk factor for postoperative pulmonary embolism after anterior cervical discectomy and fusion.

Spine J

September 2024

Virginia Tech Carilion School of Medicine, 2 Riverside Circle, Roanoke, VA 24016, USA; Department of Orthopaedic Surgery, Institute for Orthopaedics & Neurosciences, Carilion Clinic, 2331 Franklin Road Southwest, Roanoke, VA 24014, USA. Electronic address:

Article Synopsis
  • The study investigates the impact of different obesity levels on complication rates for patients undergoing anterior cervical discectomy with fusion (ACDF), using a large national database from 2011 to 2020.
  • It categorizes patients into four BMI groups (nonobese and three obesity classes) and assesses various demographic and health-related risk factors for perioperative complications.
  • The analysis involved over 64,000 patients, aiming to better understand how obesity correlates to surgical outcomes in a diverse patient population.
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Introduction: Open surgical resection involves extended recovery and soft-tissue damage, prompting the development and increasing adoption of less invasive techniques. While Mast Quadrant tubular retractors have been used in spine fusion and endoscopic procedures, their application in minimally invasive tumor resections has not been widely discussed. This report showcases the use of a Mast Quadrant tubular retractor for the minimally invasive resection of a lumbar vertebral body osteoid osteoma.

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Advanced chronic kidney disease increases complications in anterior cervical discectomies with fusions: An analysis of 75,508 patients.

N Am Spine Soc J

September 2024

Department of Orthopaedic Surgery, Institute for Orthopaedics and Neurosciences, Carilion Clinic, 2331 Franklin Road Southwest, Roanoke, VA 24014, United States.

Background: Although anterior cervical discectomy and fusion (ACDF) procedures for cervical spine disease have been increasing amid a growing population of patients with kidney dysfunction, there is a scarcity of literature focusing on kidney dysfunction as a risk-factor for post-operative ACDF complications. The purpose is to evaluate the differential impact of kidney dysfunction on perioperative outcomes including surgical and medical complications, extended length of hospital stay (LOS), and death within 30 days following ACDF.

Patient Sample: This was a retrospective cohort study of prospectively collected data using the American College of Surgeons National Surgical Quality Improvement Program database to identify patients who had undergone an elective ACDF procedure between 2011-2021 using Current Procedural Terminology code 22551.

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Surgical Approach Does Not Influence Instability Risk in Revision Total Hip Arthroplasty.

J Arthroplasty

September 2024

Department of Orthopaedic Surgery, Carilion Clinic Institute for Orthopaedics & Neurosciences, Roanoke, Virginia; Virginia Tech Carilion School of Medicine, Roanoke, Virginia.

Background: Although the direct anterior (DA) approach has increased in popularity for primary total hip arthroplasty (THA), there is limited evidence regarding its use for revision THA. It is unknown whether the dislocation benefit seen in the primary setting translates to revision cases.

Methods: This retrospective review compared the dislocation rates of revision THA performed through DA versus postero-lateral (PL) approaches at a single institution (2011 to 2021).

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Insulin dependence negatively impacts outcomes in anterior cervical discectomy with fusions: a 10-year retrospective analysis.

Spine J

October 2024

Virginia Tech Carilion School of Medicine, 2 Riverside Circle, Roanoke, VA 24016, USA; Department of Orthopaedic Surgery, Institute for Orthopaedics and Neurosciences, Carilion Clinic, 2331 Franklin Road Southwest, Roanoke, VA 24014, USA. Electronic address:

Background Context: Although anterior cervical discectomy and fusion (ACDF) procedures for cervical spine disease have been increasing amid a growing diabetic patient population, there is a paucity of literature focusing on insulin-dependence as a risk-factor for postoperative ACDF complications.

Purpose: To evaluate the differential impact of insulin dependence on perioperative outcomes including total length of stay, surgical, and medical complications within thirty days following ACDF.

Study Design/setting: A retrospective cohort, large multicenter database study.

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Soft Tissue Coverage for Foot and Ankle Trauma.

Clin Podiatr Med Surg

July 2024

Department of Orthopaedic Surgery, Virginia Tech Carilion School of Medicine, 2331 Franklin Road Southwest, Roanoke, VA 24014, USA. Electronic address:

Lower extremity trauma can result in extensive soft tissue loss, which can require a staged multispecialty approach. Flaps can be an excellent choice for significant soft tissue loss. A variety of variables goes into the selection of a flap including understanding what the recipient site needs, available donor sites, nature of trauma, and utilization of indices to predict limb salvageability in order to strategically select the correct flap option.

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Management of Pilon Fractures.

Clin Podiatr Med Surg

July 2024

Department of Surgery, Section of Orthopaedics, Carilion Clinic Institute for Orthopaedics and Neuroscience, 3 Riverside Circle, Roanoke, VA 24014, USA.

Pilon fractures are complex injuries that can be difficult to treat and lead to severe complications if not managed appropriately. A thorough examination for polytraumatic injuries, neurovascular status, and skin condition should be done. A variety of approaches can be chosen based on fracture pattern, including staging, incisional approach, and no-touch technique.

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Background: In-person hand therapy is commonly prescribed for rehabilitation after thumb carpometacarpal (CMC) arthroplasty but may be burdensome to patients because of the need to travel to appointments. Asynchronous, video-assisted home therapy is a method of care in which videos containing instructions and exercises are provided to the patient, without the need for in-person or telemedicine visits. The purpose of the present study was to evaluate the effectiveness of providing video-only therapy (VOT) as compared with scheduled in-person therapy (IPT) after thumb CMC arthroplasty.

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Intraoperative Surgeon-Administered Adductor Canal Block Is a Safe Alternative to Preoperative Anesthesiologist-Administered Adductor Canal Block in Primary Total Knee Arthroplasty.

J Arthroplasty

August 2024

Department of Orthopaedic Surgery, Institute for Orthopaedics & Neurosciences, Carilion Clinic, Roanoke, Virginia; Department of Orthopaedic Surgery, Virginia Tech Carilion School of Medicine, Roanoke, Virginia.

Background: The shift toward outpatient total knee arthroplasties (TKAs) has led to a demand for effective perioperative pain control methods. A surgeon-performed "low" adductor canal block ("low-ACB") technique, involving an intraoperative ACB, is gaining popularity due to its efficiency and early pain control potential. This study examined the transition from traditional preoperative anesthesiologist-performed ultrasound-guided adductor canal blocks ("high-ACB") to low-ACB, evaluating pain control, morphine consumption, first physical therapy visit gait distance, hospital length-of-stay, and complications.

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Background: Shoulder arthroscopy is commonly performed at ambulatory surgical centers (ASCs) with use of an interscalene block and inhaled general anesthesia (IGA). However, an alternative option known as total intravenous anesthesia with propofol (TIVA-P) has shown promising results in reducing recovery time for other surgeries. The objective of this study was to assess whether there is a clinically meaningful difference in post-anesthesia care unit phase-I (PACU-I) time following shoulder arthroscopy between patients receiving an interscalene block with IGA and those receiving an interscalene block with TIVA-P.

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What Is a Surgical Site Infection After Carpal Tunnel Release?

J Hand Surg Am

August 2024

Virginia Tech Carilion School of Medicine, Roanoke, VA; Musculoskeletal Education and Research Center, Department of Orthopaedic Surgery, Institute for Orthopaedics & Neurosciences, Carilion Clinic, Roanoke, VA. Electronic address:

Purpose: Considerable variation exists in the literature on published rates of surgical site infection (SSI) after carpal tunnel release, ranging over 20-fold, from 0.28% to 6.4%.

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Neurogenic Thoracic Outlet Syndrome: A Primer for Hand and Peripheral Nerve Surgeons.

J Hand Surg Am

June 2024

Department of Orthopaedic Surgery, Musculoskeletal Education and Research Center, Carilion Clinic Institute for Orthopaedics and Neurosciences, Roanoke, VA. Electronic address:

Neurogenic thoracic outlet syndrome is a complex condition and is commonly misunderstood. Historically, much of this confusion has been because of its grouping with other diagnoses that have little in common other than anatomic location. Modern understanding emphasizes the role of small unmyelinated C type pain and sympathetic fibers.

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Osteocutaneous Radial Forearm Flap: Harvest Technique and Prophylactic Volar Locked Plating.

Plast Reconstr Surg Glob Open

November 2023

Musculoskeletal Education and Research Center, Department of Orthopaedic Surgery, Institute for Orthopaedics and Neurosciences, Carilion Clinic, Roanoke, Va.

Background: The osteocutaneous radial forearm (OCRF) flap is a variation of the traditional radial forearm flap with incorporation of an anterolateral segment of corticocancellous bone of the radius, periosteum, and overlying skin. The OCRF flap is indicated in traumatic injuries or extirpation defects with segmental bone loss and is well suited to foot and ankle reconstruction due to its thin pliable skin.

Methods: In this single-center case series, a retrospective review was conducted to identify patients who underwent OCRF free flap for foot and ankle reconstruction that required harvest of more than 50% of the cross-sectional area of the radius with prophylactic volar locked plating of the donor site.

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Femoral Neck Fracture in a Pediatric Patient with Primary Hyperparathyroidism.

Case Rep Orthop

October 2023

Department of Orthopaedic Surgery, Institute for Orthopaedics & Neurosciences, Carilion Clinic, 2331 Franklin Road Southwest, Roanoke, Virginia 24014, USA.

Case: A previously healthy 11-year-old girl underwent expedited surgical fixation of a femoral neck fracture sustained while jump-roping. After further work up, she was diagnosed with primary hyperparathyroidism. Parathyroidectomy of a hypertrophic adenoma proved curative.

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Background: Radiocapitellar arthroplasty fills a treatment void for young patients who experience isolated capitellar fractures or radiocapitellar osteoarthritis who are not candidates for total elbow arthroplasty. The outcomes of this procedure are sparsely reported. We designed a meta-analysis to determine the utility of radiocapitellar arthroplasty with respect to functional and patient reported outcomes.

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Background: The purpose of this study was to gather information regarding current practices in the care of carpometacarpal (CMC) arthroplasty including the use of hand therapy, immobilization, and surgical technique, and to determine which factors influence these patterns.

Methods: We conducted a survey from February 24, 2022, through March 26, 2022, of 3648 currently practicing members of the American Society for Surgery of the Hand. We developed an 11-item questionnaire that contained questions about surgical technique, immobilization, and postoperative therapy utilization.

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The effect of operative time on surgical-site infection following total shoulder arthroplasty.

J Shoulder Elbow Surg

November 2023

Musculoskeletal Education and Research Center, Department of Orthopaedic Surgery, Institute for Orthopaedics and Neurosciences, Carilion Clinic, Roanoke, VA, USA. Electronic address:

Background: Many factors contribute to the risk of surgical-site infection (SSI) following total shoulder arthroplasty (TSA). Operative time is a modifiable factor that may contribute to SSI occurrence after TSA. This study aimed to determine the correlation between operative time and SSI following TSA.

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Development and Experimental Evaluation of a Novel Portable Haptic Robotic Exoskeleton Glove System for Patients with Brachial Plexus Injuries.

Rep U S

October 2022

Departments of Mechanical Engineering and Electrical and Computer Engineering, Virginia Tech, Blacksburg, VA, 24061 USA.

This paper presents the development and experimental evaluation of a portable haptic exoskeleton glove system designed for people who suffer from brachial plexus injuries to restore their lost grasping functionality. The proposed glove system involves force perception, linkage-driven finger mechanism, and personalized voice control to achieve various grasping functionality requirements. The fully integrated system provides our wearable device with lightweight, portable, and comfortable characterization for grasping objects used in daily activities.

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This paper presents the development of an exoskeleton glove system for people who suffer from brachial plexus injuries, aiming to assist their lost grasping functionality. The robotic system consists of a portable glove system and an embedded controller. The glove system consists of Linear Series Elastic Actuators (LSEA), Rotary Series Elastic Actuators (RSEA), and optimized finger linkages to provide imitated human motion to each finger and a coupled motion of the hand.

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A Reduction in Body Mass Index From ≥ 40 to < 40 Lowers Emergency Department Visits, but May Increase All-Cause Readmissions After Primary Total Hip Arthroplasty: Conflicting 90-Day Outcomes at a Single Institution.

J Arthroplasty

July 2023

Department of Orthopaedic Surgery, Virginia Tech Carilion School of Medicine, Roanoke, Virginia; Department of Orthopaedic Surgery, Institute for Orthopaedics & Neurosciences, Carilion Clinic, Roanoke, Virginia.

Background: The American Association of Hip and Knee Surgeons tasked a 2013 workgroup to provide obesity-related recommendations in total joint arthroplasty. Morbidly obese patients (body mass index (BMI) ≥ 40) seeking hip arthroplasty were determined to be at increased perioperative risk, and surgeons were recommended to encourage these patients to reduce their BMI <40 presurgery. We report the effect of instituting a 2014 BMI <40 threshold on our primary total hip arthroplasties (THAs).

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Article Synopsis
  • Digital amputation is commonly performed for infections and necrosis in high-risk patients, but there's limited data on its long-term outcomes and survivability.
  • In a study analyzing 484 digital amputations over ten years, those performed due to infection or necrosis had a significantly higher revision rate (34%) and mortality risk compared to trauma-related amputations.
  • The findings highlight that patients with additional health issues like diabetes or PVD face even greater risks, with 2, 5, and 10-year survival rates significantly lower than the general population.
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