7 results match your criteria: "Cardiovascular Research Institute Maastricht and Maastricht University Medical Center[Affiliation]"

Venous thromboembolism (VTE) is a life-threatening disease with risk of recurrence. Oral anticoagulation (OAC) with vitamin K antagonists (VKA) is effective to prevent thromboembolic recurrence. We aimed to investigate the quality of OAC of VTE patients in regular medical care (RMC) compared to a telemedicine-based coagulation service (CS).

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Patients with heart failure (HF) are frequently anti-coagulated with vitamin K-antagonists (VKAs). The use of long-acting VKA may be preferable for HF patients due to higher stability of plasma concentrations. However, evidence on phenprocoumon-based oral anti-coagulation (OAC) therapy in HF is scarce.

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Sustained atrial fibrillation increases the risk of anticoagulation-related bleeding in heart failure.

Clin Res Cardiol

December 2018

Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center Mainz, Johannes Gutenberg-University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.

Background: Oral anticoagulation therapy in individuals with atrial fibrillation (AF) reduces the risk of thromboembolic events at cost of an increased bleeding risk. Whether anticoagulation-related outcomes differ between patients with paroxysmal and sustained AF receiving anticoagulation is controversially discussed.

Methods: In the present analysis of the prospective multi-center cohort study thrombEVAL, the incidence of anticoagulation-related adverse events was analyzed according to the AF phenotype.

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Unlabelled: Essentials e-Health based health care by an expert centre may advance management of oral anticoagulation. Outcome of patients was compared between an e-health based coagulation service and regular care. Patients in the coagulation service cohort experienced a significantly better clinical outcome.

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Background: The majority of studies on quality of oral anticoagulation (OAC) therapy with vitamin K-antagonists are performed with short-acting warfarin. Data on long-acting phenprocoumon, which is frequently used in Europe for OAC therapy and is considered to enable more stable therapy adjustment, are scarce. In this study, we aimed to assess quality of OAC therapy with phenprocoumon in regular medical care and to evaluate its potential for optimization in a telemedicine-based coagulation service.

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Article Synopsis
  • The hollow-fibre oxygenator is crucial for cardiopulmonary bypass during heart surgery, affecting pressure and flow quality due to energy losses.
  • A study involved 23 adult patients divided into two groups based on the type of oxygenator: one with high resistance/low compliance (Group 1) and another with low resistance/high compliance (Group 2).
  • Results showed a significant pressure decline in both groups during surgery, with similar mean radial artery pressures, indicating that while the lower resistance oxygenator had lower energy transfer, both types resulted in considerable loss of pump energy; thus, removing the oxygenator could enhance energy transfer.
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