6 results match your criteria: "Cardiology I University Medical Center Mainz Mainz Germany.[Affiliation]"
Objectives: Vertigo describes symptoms of abnormal movement of the environment or the patient's own body. As such, it affects patients' quality of life, prevents them from following their daily activities, and increases healthcare utilization. The Global Burden of Disease Project aims to quantify morbidity and mortality worldwide.
View Article and Find Full Text PDFOne-Year Outcomes According to Mitral Regurgitation Etiology Following Transcatheter Edge-to-Edge Repair With the PASCAL System: Results From a Multicenter Registry.
J Am Heart Assoc
December 2023
University of Cologne, Faculty of Medicine and University Hospital Cologne, Clinic III for Internal Medicine Cologne Germany.
Article Synopsis
- The study examined 1-year outcomes of the PASCAL system for treating severe mitral regurgitation (MR) among 282 patients with various etiologies of MR (degenerative, functional, or mixed) across multiple centers in Germany.
- Results showed significant reductions in MR immediately after the procedure, at 30 days, and sustained improvements at 1 year, with variations based on the specific cause of MR.
- Patients with degenerative MR had less pronounced MR reduction and a higher rate of complex valve morphology, indicating more challenging cases, while overall, there was notable improvement in heart function across all types of MR.
A rare case of right heart failure with the necessity for veno-arterial extracorporeal membrane oxygenation following pulmonary vein stenosis after radiofrequency ablation for atrial fibrillation.
Pulm Circ
January 2023
Department of Cardiology, Cardiology I University Medical Center Mainz Mainz Germany.
Article Synopsis
- Pulmonary vein stenosis (PVS) can occur after a procedure called pulmonary vein isolation for atrial fibrillation, with reported prevalence rates varying widely from 0% to 42%.
- Symptoms of PVS are often vague and can include shortness of breath, cough, and chest pain, which may lead to misdiagnosis and delayed treatment.
- A case study highlights a severe instance of PVS in a 59-year-old woman who required advanced treatments like stenting and ECMO support, emphasizing the importance of early diagnosis and intervention for potentially life-threatening complications.
Article Synopsis
- The study investigates the role of brain-derived neurotrophic factor (BDNF) in perivascular adipose tissue (PVAT) of patients with coronary atherosclerosis, highlighting its potential impact on vascular functions.
- BDNF levels were found to be significantly higher in the PVAT surrounding the proximal aorta (C-PVAT) compared to that around the internal mammary artery (IMA-PVAT), suggesting a localized effect independent of obesity or inflammation.
- The findings indicate that signaling through BDNF's receptor (TrkB) may be impaired in coronary atherosclerosis, as evidenced by reduced TrkB expression and elevated levels of a negative regulator of TrkB signaling in C-PVAT.
Background Preclinical data have indicated a link between use of vitamin K antagonists ( VKA ) and detrimental effects on vascular structure and function. The objective of the present study was to determine the relationship between VKA intake and different phenotypes of subclinical cardiovascular disease in the population. Methods and Results Clinical and laboratory data, as well as medical-technical examinations were assessed from 15 010 individuals aged 35 to 74 years during a highly standardized 5-hour visit at the study center of the population-based Gutenberg Health Study.
View Article and Find Full Text PDF