4 results match your criteria: "Cardiology Division Massachusetts General Hospital Harvard Medical School Boston MA.[Affiliation]"
Article Synopsis
- Young patients with diabetes have a significantly higher prevalence of vulnerable plaque characteristics linked to acute coronary syndrome compared to those without diabetes.
- The study analyzed 1,394 patients and found that diabetes was associated with more lipid-rich plaques and other harmful features, which remained high across different age groups.
- While patients without diabetes showed increased plaque rupture and lipid-rich plaques as they aged, those with diabetes exhibited these risks early on, indicating a need for early intervention.
Background Seasonal variations in acute coronary syndromes (ACS) have been reported, with incidence and mortality peaking in the winter. However, the underlying pathophysiology for these variations remain speculative. Methods and Results Patients with ACS who underwent optical coherence tomography were recruited from 6 countries.
View Article and Find Full Text PDFOver the past decade, the field of valvular heart disease (VHD) has rapidly transformed, largely as a result of the development and improvement of less invasive transcatheter approaches to valve repair or replacement. This transformation has been supported by numerous well-designed randomized trials, but they have centered almost entirely on devices and procedures. Outside this scope of focus, however, myriad aspects of therapy and management for patients with VHD have either no guidelines or recommendations based only on expert opinion and observational studies.
View Article and Find Full Text PDFBackground Plaque erosion is responsible for 25% to 40% of patients with acute coronary syndromes (ACS). Recent studies suggest that anti-thrombotic therapy without stenting may be an option for this subset of patients. Currently, however, an invasive procedure is required to make a diagnosis of plaque erosion.
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