Knowledge and Practices Regarding Dietary Supplements Among Healthcare Professionals in Poland.

Introduction: The growing popularity of dietary supplements in Poland raises the need to verify the knowledge and practices of healthcare workers who have a key role in recommending their use. Understanding these issues is important to ensure patient safety and the correct use of dietary supplements. Therefore, the aim of the study was to examine the level of knowledge, practices, and sources of information on dietary supplements among various professional groups of healthcare workers.

The Impact of Neutrophil-to-High-Density Lipoprotein Ratio and Serum 25-Hydroxyvitamin D on Ischemic Heart Disease.

This study describes the complex association between the neutrophil-to-high-density lipoprotein cholesterol ratio (NHR), 25-hydroxyvitamin D (25(OH)D) levels, and cardiovascular disease (CVD), such as stable ischemic heart disease (IHD), ST elevation myocardial infarction (STEMI), non-ST-segment elevation myocardial infarction (NSTEMI), and unstable angina (UA). The serum 25(OH)D concentration and NHR values were analyzed in groups of patients with chronic coronary syndrome (CCS) and acute coronary syndrome (ACS). The severity of coronary artery atherosclerosis was determined using the Coronary Artery Surgery Study (CASS) scale.

Evaluation of Lateral and Medial Parts of the Hamstring Muscle Fatigue Symmetry in Professional Footballers Cleared to Play After ACL Reconstruction.

Rupture of the anterior cruciate ligament (ACL) is a severe injury common in sports. It also has a high rate of re-injury. The aim of this work was to assess hamstring muscle fatigue in active football players after ACL reconstruction who were cleared to play and to determine symmetry between the lateral and medial hamstring muscles.

Advancing Pharmaceutical Care in Community Pharmacies in Poland: A Blueprint for Enhanced Patient Care Quality.

: This article reviews the current state of pharmaceutical care in community pharmacies in Poland and proposes a collaborative framework for its advancement. While pharmaceutical care has evolved significantly worldwide, with Europe leading the way, Poland has lagged in its development. Although Polish pharmacists are well-qualified and community pharmacies are numerous, pharmaceutical care remains underdeveloped.

Oncosexology - selected issues taking into account the problem of sexological care of patients with cancer.

As can be seen from research, 44% of oncological problems disclose problems in relationships with a partner. About 80% of oncological patients report deterioration of the quality of their sexual life. Although the situation improves, a significant majority of ill persons do not obtain assistance in the scope of sexuality during oncological treatment.

Evaluation of stiffness-matched, 3D-printed, NiTi mandibular graft fixation in an ovine model.

Background: Manually bent, standard-of-care, Ti-6Al-4V, mandibular graft fixation devices are associated with a significant post-operative failure rate. These failures require the patient to endure stressful and expensive re-operation. The approach recommended in this report demonstrates the optimization of graft fixation device mechanical properties via "stiffness-matching" by varying the fixation device's location, shape, and material composition through simulation of the device's post-operative performance.

Optimizing Urological Concurrent Robotic Multisite Surgery: Juxtaposing a Single-Center Experience and a Literature Review.

: This article juxtaposes case series with a systematic review to evaluate the feasibility, safety, and clinical outcomes of concurrent robotic multisite urological surgeries, specifically robot-assisted radical prostatectomy (RARP) and robot-assisted partial nephrectomy (RAPN), for synchronous prostate and kidney cancers. : The aims of this study were to evaluate the feasibility, safety, and clinical outcomes of urological concurrent robotic multisite surgeries through a comparison of institutional findings with the existing literature. : A retrospective analysis was conducted on eight institutional cases of concurrent robotic multisite surgeries performed between 2021 and 2024.

Sterically Tuned -Phenylene-Linked Donor-Acceptor Benzothiazole-Based Boron Difluoride Complexes as Thermally-Activated Delayed Fluorescence Emitters for Organic Light-Emitting Diodes.

Two donor-acceptor dyes with an -phenylene-linked carbazole electron donor and a benzothiazole-fused boron heterocyclic acceptor were designed, synthesized, and spectroscopically investigated. Due to the steric effects of boron heterocyclic units, the dyes demonstrate different conformations in the crystalline state. The presence of numerous hydrogen-bonding intermolecular interactions and the very weak π-π stacking in the molecular packing results in intense solid-state emission with photoluminescence quantum yields of 40 and 18% for crystals and 50 and 42% for host-based light-emitting layers.

DNA methylation at AHRR as a master predictor of smoke exposure and a biomarker for sleep and exercise.

Background: DNA methylation profiling may provide a more accurate measure of the smoking status than self-report and may be useful in guiding clinical interventions and forensic investigations. In the current study, blood DNA methylation profiles of nearly 800 Polish individuals were assayed using Illuminia EPIC and the inference of smoking from epigenetic data was explored. In addition, we focused on the role of the AHRR gene as a top marker for smoking and investigated its responsiveness to other lifestyle behaviors.

Depression and Obesity-Do We Know Everything about It? A Narrative Review.

Introduction: Due to similarities in their pathophysiology and common psychological background, depressive disorders and obesity often occur simultaneously. The treatment of obesity can reduce the symptoms of comorbid depression and, conversely, treating depression can improve weight reduction outcomes.

Purpose Of This Study: This review aimed to analyze the available literature on the subject of various methods of treating obesity and comorbid depression and to demonstrate the mutual correlation between the therapy of depressive disorders and the therapy of obesity.

Health Attitudes of Women Living in Religious Communities-A Preliminary Study.

Introduction: Members of consecrated life communities exhibit homogeneity with regard to factors that are relevant to health, including diet, daily activities, religiosity, and housing. This may be indicative of the manner in which the community influences the formation of the health-seeking attitudes of its members.

Purpose Of The Study: The objective of this study was to validate a survey about health awareness and health-seeking attitudes among consecrated people and to identify potential issues to be improved.

Selected aspects of the sexual functioning of women - preliminary studies.

Introduction: Sexology is a field of study to which too little attention has been paid over the years. It is still regarded as relatively new and is constantly expanding. Undoubtedly, sexual health affects a person's overall heath, influencing not only the development of a person's personality, but also their social communication skills and ability to love.

Personalization of pharmacotherapy with sirolimus based on volumetric absorptive microsampling (VAMS) in pediatric renal transplant recipients-from LC-MS/MS method validation to clinical application.

Background: The benefits of pharmacotherapy with sirolimus (SIR) in pediatric transplant recipients are well established. Traditionally, whole blood samples have been used to measure SIR concentrations. Volumetric Absorptive Microsampling (VAMS) is an alternative sampling strategy suitable for Therapeutic Drug Monitoring (TDM).

The notion and practice of psychotherapy in Polish psychiatry of the interwar period. Part 2.

The paper further explores the development of psychotherapy in Polish psychiatry in the interwar period. Jaroszyński attempted to sketch out the idea of "emotional psychotherapy". Stryjeński organized a counseling clinic for the mentally ill, using psychotherapy as one of the means of treatment.

The notion and practice of psychotherapy in Polish psychiatry of the interwar period. Part 1.

The paper explores the development of psychotherapy in Polish psychiatry in the interwar period from the perspective of Kurt Danziger's historical psychology. Firstly, the organizational and social context of the development of Polish psychiatric care in the interwar period and its impact on the development of psychotherapy is outlined. Then, the most influential in Poland, European psychotherapeutic developments in the interwar period are reconstructed.

Characteristics of dental malocclusion in a 18th/19th century population from Radom (Poland).

Objective: The aim of the study was to assess the diachronicity of factors that produce malocclusion from the 18th century to the present.

Materials: A total of 74 adult individuals Radom (Poland) of both sexes were examined (males: 46, females: 28).

Methods: The skulls were grouped according to the type of malocclusion found: i) anterio-posterior (skeletal Class I/II/III), ii) transverse (cross bite/scissor bite), and iii) vertical (open bite/deep bite).

An analysis of health policy programmes on eye health implemented by Local Government Units (LGUs) in Poland, 2015-2023.

Introduction And Objective: Local Government Units (LGUs) in Poland may develop health policy programs on different health conditions according to the rules and templates defined by the Agency for Health Technology Assessment and Tariff System (AHTATS). This study aimed to analyze health policy programs on eye health implemented by LGUs in Poland between 2015 and 2023.

Material And Methods: This is a retrospective analysis of data on health policy programs on eye health implemented by LGUs in Poland from 1 January 2015 to 31 December 2023.

Changes in body weight in various population groups in Poland during the COVID-19 pandemic - a comparison of two cross-sectional studies.

Introduction And Objective: The disruption of daily activities caused by the COVID-19 pandemic had health consequences, especially during peak lockdown periods. The aim of the study is to assess the impact of the first year of the COVID-19 pandemic on the process of weight change among Polish adults.

Material And Methods: Two representative studies involving Polish adults aged 18-65 years were conducted, the first in June 2020 (N = 2527, from the perspective of the last 2-3 months), and the second a year later, in June 2021 (N = 2087, covering the last 12 months).

Synthesis and Structure of 5-Methyl-9-(trifluoromethyl)-12-quino[3,4-][1,4]benzothiazinium Chloride as Anticancer Agent.

In this work, the synthesis, structural analysis and anticancer properties of 5-methyl-9-trifluoromethyl-12-quino[3,4-][1,4]benzothiazinium chloride () are described. Compound was synthesized by reacting 1-methyl-4-butylthio-3-(benzoylthio)quinolinium chloride with 4-(trifluoromethyl)aniline, respectively. The structure of the resulting product was determined using H-NMR and C-NMR spectroscopy as well as HR-MS spectrometry.

Synergetic Effect of β-Cyclodextrin and Its Simple Carbohydrate Substituents on Complexation of Folic Acid and Its Structural Analog Methotrexate.

Folic acid (FA) and its structural analog, anticancer medicine methotrexate (MTX), are known to form host/guest complexes with native cyclodextrins, of which the most stable are formed with the medium-sized β-cyclodextrin. Based on our research, proving that simple sugars (D-glucose, D-galactose, and D-mannose) can form adducts with folic acid, we envisioned that combining these two types of molecular receptors (cyclodextrin and simple carbohydrates) into one may be beneficial for the complexation of FA and MTX. We designed and obtained host/guest inclusion complexes of FA and MTX with two monoderivatives of β-cyclodextrin-substituted at position 6 with monosaccharide (glucose, G-β-CD) and disaccharide (maltose, Ma-β-CD).