Crystal structure and Hirshfeld surface analysis of (3a,6,6a,7,11b,11c)-2,2-dibenzyl-2,3,6a,11c-tetra-hydro-1,6,7-3a,6:7,11b-di-epoxy-dibenzo[,]isoquinolin-2-ium tri-fluoro-methane-sulfonate.

In the cation of the title salt, CHNO ·CFOS, the four tetra-hydro-furan rings adopt envelope conformations. In the crystal, pairs of cations are linked by dimeric C-H⋯O hydrogen bonds, forming two (6) ring motifs parallel to the (001) plane. The cations and anions are connected by further C-H⋯O hydrogen bonds, forming a three-dimensional network structure.

Public perceptions about nurses communicated via Twitter in Turkey.

Objectives: Social media platforms such as Twitter allow people to openly express their views about many topics, including the nursing profession. COVID-19 is currently a frequently searched and discussed topics on Twitter. This study was performed to identify the image of nursing in the social media before and during COVID-19 pandemic in Turkey, and to review of public perceptions about nurses' communication on twitter in Turkey.

Crystal structure and Hirshfeld surface analysis of 2,2,2-tri-chloro-,-bis-{[(1,4)-1,4-di-hydro-1,4-ep-oxy-naphthalen-1-yl]meth-yl}acetamide.

In the title compound, CHClNO, the tetra-hydro-furan rings adopt envelope conformations. In the crystal, C-H⋯O hydrogen bonds connect mol-ecules, generating layers parallel to the (001) plane. These layers are connected along the axis direction by C-H⋯π inter-actions.

Crystal structure and Hirshfeld surface analysis of ()-4-({2,2-di-chloro-1-[4-(di-methyl-amino)-phen-yl]ethenyl}diazen-yl)benzo-nitrile.

In the title compound, CHClN, the dihedral angle between the aromatic rings is 50.09 (9)°. The central -N=N- unit shows an configuration.

Antimicrobial peptides (AMPs): A promising class of antimicrobial compounds.

Antimicrobial peptides (AMPs) are compounds, which have inhibitory activity against microorganisms. In the last decades, AMPs have become powerful alternative agents that have met the need for novel anti-infectives to overcome increasing antibiotic resistance problems. Moreover, recent epidemics and pandemics are increasing the popularity of AMPs, due to the urgent necessity for effective antimicrobial agents in combating the new emergence of microbial diseases.

Recombinant expression and coexpression of oyster defensin and proline-rich peptide in Komagataella phaffii.

Proline-rich peptide (CgPrp) and defensin (CgDef), oyster (Crassostrea gigas)-originated antimicrobial peptides (AMPs), were produced by the recombinant technique in Komagataella phaffii GS115 cells. For this purpose, the nucleotide sequences encoding the CgPrp and CgDef peptides were synthesized by the recursive PCR technique, and ligated in pPICZaA expression vector. Additionally, the expression cassettes of pPICZαA-CgDef and pPICZαA-CgPrp were combined using in vitro multimer ligation strategy to construct the coexpression vector pPICZaA-CgPrp-CgDef.

Crystal structure and Hirshfeld surface analysis of ()-1-[2,2-di-chloro-1-(4-methyl-phen-yl)ethen-yl]-2-(4-meth-oxy-phen-yl)diazene.

The asymmetric unit of the title compound, CHClNO, comprises two similar mol-ecules, and , in which the dihedral angles between the two aromatic rings are 70.1 (3) and 73.2 (2)°, respectively.

Crystal structure and Hirshfeld surface analysis of (3)-7-meth-oxy-3-(2-phenyl-hydrazinyl-idene)-1-benzo-furan-2(3)-one.

In the title compound, CHNO, pairs of mol-ecules are linked into dimers by N-H⋯O hydrogen bonds, forming an (12) ring motif, with the dimers stacked along the axis. These dimers are connected through π-π stacking inter-actions between the centroids of the benzene and furan rings of their 2,3-di-hydro-1-benzo-furan ring systems. Furthermore, there exists a C-H⋯π inter-action that consolidates the crystal packing.

Associations between Turkish incarcerated mothers' sensitivity and their co-residing children's attachment: The moderating role of children's temperament.

This study investigated the associations between incarcerated mothers' sensitivity and their co-residing children's attachment security. Furthermore, the moderating role of children's temperament on the associations between maternal sensitivity and children's attachment security was examined. The study sample consisted of 84 incarcerated mothers ( = 29.

Crystal structure and Hirshfeld surface analysis of dimethyl 5-[2-(2,4,6-trioxo-1,3-diazinan-5-yl-idene)hydrazin-1-yl]benzene-1,3-di-carboxyl-ate 0.224-hydrate.

In the crystal, the whole mol-ecule of the title compound, CHNO·0.224HO, is nearly planar with a maximum deviation from the least-squares plane of 0.352 (1) Å.

Crystal structure and Hirshfeld surface analysis of (2)-,-dimethyl-2-(penta-fluoro-phen-yl)-2-(2-phenyl-hydrazin-1-yl-idene)acetamide.

In the title compound, CHFNO, the dihedral angle between the aromatic rings is 31.84 (8)°. In the crystal, the mol-ecules are linked into dimers possessing crystallographic twofold symmetry by pairwise N-H⋯O hydrogen bonds and weak C-H⋯O hydrogen bonds and aromatic π-π stacking inter-actions link the dimers into a three-dimensional network.

Crystal structure and Hirshfeld surface analysis of 1,3-bis-{2,2-di-chloro-1-[()-phenyl-diazen-yl]ethen-yl}benzene.

In the mol-ecule of the title compound, CHClN, the central benzene ring makes dihedral angles of 77.03 (9) and 81.42 (9)° with the two approximately planar 2,2-di-chloro-1-[()-phenyl-diazen-yl]vinyl groups.

Crystal structure and Hirshfeld surface analysis of (3a,4,7,7a)-4,5,6,7,8,8-hexa-chloro-2-{6-[(3a,4,7,7a)-4,5,6,7,8,8-hexa-chloro-1,3-dioxo-1,3,3a,4,7,7a-hexa-hydro-2-4,7-methano-isoindol-2-yl]hex-yl}-3a,4,7,7a-tetra-hydro-1-4,7-methano-iso-indole-1,3(2)-dione.

The mol-ecule of the title compound, CHClNO, is generated by a crystallographic inversion centre at the midpoint of the central C-C bond. A kink in the mol-ecule is defined by a torsion angle of -169.86 (15)° about this central bond of the alkyl bridge.

Innovation in measuring obese patients' blood pressure: measurement with conical wrapping technique.

Introduction: Accurate measurement of blood pressure (BP) is difficult in obese patients due to their upper arm shape and width. Errors made during BP measurement cause misdiagnosis or lead to wrong treatment.

Method: The data of this methodological study were collected from 40 patients who were 18 years old or above, with a BMI above 25 kg/m2, and who were followed up with radial catheter arterial pressure in adult intensive care and postoperative care units between March and December 2020.

Crystal structure and Hirshfeld surface analysis of 5,7-diphenyl-1,2,3,5,6,7-hexa-hydro-imidazo[1,2-]pyridine-6,6,8-tricarbo-nitrile methanol mono-solvate.

In the title compound, CHN·CHO, the imidazolidine ring of the 1,2,3,5,6,7-hexa-hydro-imidazo[1,2-]pyridine ring system is a twisted envelope, while the 1,2,3,4-tetra-hydro-pyridine ring adopts a twisted boat conformation. In the crystal, pairs of mol-ecules are linked by O-H⋯N and N-H⋯O hydrogen bonds two methanol mol-ecules, forming a centrosymmetric (16) ring motif. These motifs are connected to each other by C-H⋯N hydrogen bonds and form columns along the axis.

Effects of nocturnal complete denture usage on cardiorespiratory parameters: A pilot study.

Statement Of Problem: Sleeping without conventional complete dentures (CCDs) has been stated by some to induce negative effects on the cardiorespiratory functions of edentulous patients with obstructive sleep apnea (OSA), although others have reported the exact opposite. Therefore, a consensus on nocturnal CCD usage is lacking.

Purpose: The purpose of this clinical study was to assess the effects of nocturnal denture usage on cardiorespiratory stability by using pulse oximetry (PO).

Crystal structure and Hirshfeld analysis of di--butyl 2,2'-[(ethyl-aza-nedi-yl)bis-(methyl-ene)]bis-(1-pyrrole-1-carboxyl-ate).

The title compound, CHNO, crystallizes in the triclinic space group with two mol-ecules in a unit cell. The two pyrrole rings are essentially planar (r.m.

[Investigation of Ganciclovir Resistance in Cytomegalovirus Strains Obtained from Immunocompromised Patients].

CMV is a virus that is asymptomatic in healthy individuals but can cause serious mortality and morbidity in transplant patients and patients with acquired immunodeficiency syndrome (AIDS). Ganciclovir (GCV) is a nucleoside analog that significantly reduces morbidity and mortality in CMV-related infections and is used as the first choice in treatment. It is the first drug shown to be effective in the treatment of CMV disease in humans, and is also homologous to acyclovir.

()-1-(2,6-Di-chloro-phen-yl)-2-(3-nitro-benzyl-idene)hydrazine: crystal structure and Hirshfeld surface analysis.

The stabilized conformation of the title compound, CHClNO, is similar to that of the isomeric compound ()-1-(2,6-di-chloro-phen-yl)-2-(2-nitro-benzyl-idene)hydrazine. The 2,6-di-chloro-phenyl ring and the nitro-substituted benzene ring form a dihedral angle of 26.25 (16)°.

Crystal structure and Hirshfeld surface analysis of 4-{2,2-di-chloro-1-[()-(4-chloro-phen-yl)diazen-yl]ethen-yl}-,-di-methyl-aniline.

The title compound, CHClN, comprises three mol-ecules of similar shape in the asymmetric unit. The crystal cohesion is ensured by inter-molecular C-H⋯N and C-H⋯Cl hydrogen bonds in addition to C-Cl⋯π inter-actions. Hirshfeld surface analysis and two-dimensional fingerprint plots reveal that Cl⋯H/H⋯Cl (33.

Investigations of antiproliferative and antioxidant activity of β-lactam morpholino-1,3,5-triazine hybrids.

This article reports for the first time the synthesis of some novel β-lactam morpholino-1,3,5-triazine hybrids by a [2+2]-cycloaddition reaction of imines 7a-c, 9a-c and 11 with ketenes derived from substituted acetic acids. The reaction was totally diastereoselective, leading exclusively to the formation of cis-β-lactams 8a-l, 10a-f and 12a-c. The synthesized compounds were tested for activity towards SW1116, MCF-7 and HepG2 cancer cell lines and non-cancerous HEK-293 cell line by MTT assay.

The pathway to care of patients with SUD who presented at addiction treatment centers (AMATEM) in Turkey.

Aim: Recent studies have shown that alcohol and drug use in Turkey is rising year on year. In order to prevent and treat substance use disorder (SUD), many Alcohol and Drug Research, Treatment and Training Centres (AMATEM) have been established in Turkey. The purpose of this study was to investigate the pathway to care of patients who presented at AMATEM.

Designing siRNA-conjugated plant oil-based nanoparticles for gene silencing and cancer therapy.

In this study, the anticancer activities of two siRNA carriers were compared using a human lung adenocarcinoma epithelial cell line (A549). Firstly, poly(styrene)-graft-poly(linoleic acid) (PS--PLina) and poly(styrene)-graft-poly(linoleic acid)-graft-poly(ethylene glycol) (PS--PLina--PEG) graft copolymers were synthesized by free-radical polymerization. PS-PLina and PS-PLina-PEG nanoparticles (NPs) were prepared by solvent evaporation method and were then characterized.

Crystal structure and Hirshfeld surface analysis of di-iodido-{'-[()-(phen-yl)(pyridin-2-yl-κ)methylidene]pyridine-2-carbohydrazide-κ ',}cadmium(II).

In each of the two independent mol-ecules in the asymmetric unit of the title compound, [CdI(CHNO)], the ,,'-tridentate '-[()-(phen-yl)(pyridin-2-yl-κ)methyl-idene]pyridine-2-carbohydrazide ligand and two iodide anions form an INO penta-coordination sphere, with a distorted square-pyramidal geometry, with an I atom in the apical position. Both mol-ecules feature an intra-molecular N-H⋯N hydrogen bond. In the crystal, weak aromatic π-π stacking inter-actions [centroid-centroid separation = 3.

Crystal structure and Hirshfeld surface analysis of ()-3-[(4-fluoro-benzyl-idene)amino]-5-phenyl-thia-zolidin-2-iminium bromide.

In the cation of the title salt, CHFNS·Br, the phenyl ring is disordered over two sets of sites with a refined occupancy ratio of 0.503 (4):0.497 (4).