Boric Acid Protects the Uterus and Fallopian Tubes from Cyclophosphamide-Induced Toxicity in a Rat Model.

: Cyclophosphamide (CP) is widely used for treating various cancers and autoimmune diseases, but it causes damage to reproductive organs due to oxidative stress (OS) and inflammation. Boric acid (BA) has antioxidant properties that may help reduce OS, which is critical for preserving uterine functionality, particularly for cancer patients considering pregnancy after cryopreservation. This study aimed to determine whether BA could diminish CP-induced toxicity in the uterus and fallopian tubes (FT) using CP-induced toxicity in a rat model.

Nursing students' metaphorical perceptions of professional communication and the concept of nursing in their first clinical practice: qualitative research.

Background: Nursing education combines theoretical knowledge and clinical practice to prepare nursing students to meet the evolving demands of healthcare services. Understanding nursing students' metaphorical perceptions of the nursing profession and professional communication during their first clinical experiences can provide valuable insights into their professional identity and communication skills, as well as giving information about necessary improvements in nursing education. This study aimed to reveal the metaphorical perceptions of nursing students regarding the concepts of professional communication and nursing during their first clinical practices.

Utilization of beef lung powder in model chicken emulsion formulation.

The present study aimed to demonstrate the effect of beef lung powder addition to model chicken emulsion formulations on quality parameters and determine the optimum usage dose. A mixture design method was employed to determine the ideal proportions of chicken meat, animal fat, and water. The optimal formulation comprises 70.

Validation of the Acoustic Voice Quality Index Version 03.01 in Turkish.

Objectives: The aim of this study was to validate the Acoustic Voice Quality Index (AVQI) version 3.01 in the Turkish-speaking population.

Materials And Methods: Concatenated voice samples of the sustained vowel [a:] and continuous speech were collected from 127 dysphonic and 128 normophonic participants.

The effectiveness of relaxation exercises on fatigue in hemodialysis patients: a meta-analysis study.

Objective: This study was conducted to determine the effect of relaxation exercise on fatigue symptoms in hemodialysis patients.

Methods: This is a meta-analysis study. The literature review was carried out by searching studies published between 2011 and 2020.

α-glucosidase, docking and density functional theory studies on novel azide metal complexes.

The goal of this study is to synthesize new metal complexes containing -methyl-1-(pyridin-2-yl)methanimine and azide ligands as α-glucosidase inhibitors for Type 2 diabetes. The target complexes () were synthesized by reacting -methyl-1-(pyridin-2-yl)methanimine (L) with sodium azide in the presence of corresponding metal salts. The investigation of target protein interactions, vibrational, electronic and nonlinear optical properties for these complexes was performed by molecular docking and density functional theory studies.

"Lombard Effect" and Voice Changes in Adductor Laryngeal Dystonia: A Pilot Study.

Objectives: The aim was to describe the acoustic, auditory-perceptive, and subjective voice changes under the Lombard effect (LE) in adductor laryngeal dystonia (AdLD) patients.

Methods: Subjective perception of vocal effort (OMNI Vocal Effort Scale OMNI-VES), Maximum Phonation Time (MPT), and the perceptual severity of dysphonia (GRBAS scale) were assessed in condition of stillness and under LE in 10 AdLD patients and in 10 patients with typical voice. Speakers were asked to produce the sustained vowel /a/ and to read a phonetically balanced text aloud.

Crystal structures and Hirshfeld surface analyses of methyl 4-{2,2-di-chloro-1-[()-phenyl-diazen-yl]eth-enyl}benzoate, methyl 4-{2,2-di-chloro-1-[()-(4-methyl-phen-yl)diazen-yl]ethen-yl}benzoate and methyl 4-{2,2-di-chloro-1-[()-(3,4-di-methyl-phen-yl)diazen-yl]ethen-yl}benzoate.

The crystal structures and Hirshfeld surface analyses of three similar azo compounds are reported. Methyl 4-{2,2-di-chloro-1-[()-phenyl-diazen-yl]ethen-yl}benzoate, CHClNO, (), and methyl 4-{2,2-di-chloro-1-[()-(4-methyl-phen-yl)diazen-yl]ethen-yl}benzoate, CHClNO, (), crystallize in the space group 2/ with = 4, and methyl 4-{2,2-di-chloro-1-[()-(3,4-di-methyl-phen-yl)diazen-yl]ethen-yl}benzoate, CHClNO, (), in the space group with = 2. In the crystal of (), mol-ecules are linked by C-H⋯N hydrogen bonds, forming chains with (6) motifs parallel to the axis.

Crystal structure and Hirshfeld surface analysis of ()-2-[2-(2-amino-1-cyano-2-oxo-ethyl-idene)hydrazin-1-yl]benzoic acid ,-di-methylformamide monosolvate.

In the title compound, CHNO·CHNO, the asymmetric unit contains two crystallographically independent mol-ecules and , each of which has one DMF solvate mol-ecule. Mol-ecules and both feature intra-molecular N-H⋯O hydrogen bonds, forming (6) ring motifs and consolidating the mol-ecular configuration. In the crystal, N-H⋯O and O-H⋯O hydrogen bonds connect mol-ecules and , forming (8) ring motifs.

Comparison of antimicrobial efficacy of different disinfectants on the biofilm formation in dental unit water systems using dip slide and conventional methods: A pilot study.

Objective: Biofilm formation in dental waterlines brings opportunistic infections, especially for immunosuppressive patients. This study aimed to determine biofilm-forming microorganisms by various methods and investigate disinfectants' effects on biofilm.

Materials & Methods: In the study, samples were obtained from the waterlines of 10-15 aged six dental units, before (0 min.

Crystal structure and Hirshfeld surface analysis of 10-hy-droxy-2-(4-meth-oxy-phen-yl)-3-oxo-2,3,3a,4,10,10a-hexa-hydro-1-9-thia-2-aza-cyclo-penta-[]fluorene-4-carb-oxy-lic acid dimethyl sulfoxide- monosolvate.

In the title compound, CHNOS·CDOS, the central six-membered ring has a slightly distorted boat conformation, while the fused pyrrolidine ring adopts an envelope conformation. These conformations are stabilized by O-H⋯O hydrogen bonds between the main compound and solvent mol-ecules. In addition, intra-molecular C-H⋯O hydrogen bonds in the main mol-ecule form two (6) rings.

Crystal structure of [1,3-bis-(2,4,6-tri-methyl-phen-yl)imidazolidin-2-yl-idene]di-chlorido-(2-{[(2-methoxyeth-yl)(meth-yl)amino]-meth-yl}benzyl-idene)ruth-en-ium.

The title compound, [RuCl(CHNO)], is an example of a new generation of ,-dialkyl ruthenium catalysts with an N-Ru coordination bond as part of a six-membered chelate ring. The Ru atom has an Addison τ parameter of 0.244, which indicates a geometry inter-mediate between square-based pyramidal and trigonal-bipyramidal.

Crystal structure and Hirshfeld surface analysis of dimethyl 4-hy-droxy-5,4'-dimethyl-2'-(toluene-4-sulfonyl-amino)-biphenyl-2,3-di-carboxyl-ate.

In the title compound, CHNOS, the mol-ecular conformation is stabilized by intra-molecular O-H⋯O and N-H⋯O hydrogen bonds, which form (6) and (8) ring motifs, respectively. The mol-ecules are bent at the S atom with a C-SO-NH-C torsion angle of -70.86 (11)°.

Crystal structure and Hirshfeld surface analysis of dieth-yl (3a,31,4,5,6,6a,7,9a)-3a1,5,6,6a-tetra-hydro-1,3,4,7-3a,6:7,9a-di-epoxy-benzo[]isochromene-4,5-di-carboxyl-ate.

In the title compound, CHO, two hexane rings and an oxane ring are fused together. The two hexane rings tend toward a distorted boat conformation, while the tetra-hydro-furan and di-hydro-furan rings adopt envelope conformations. The oxane ring is puckered.

Crystal structure and Hirshfeld surface analysis of 3-benzyl-2-[bis(1-pyrrol-2-yl)methyl]thiophene.

In the title compound, CHNS, the asymmetric unit comprises two similar mol-ecules ( and ). In mol-ecule , the central thio-phene ring makes dihedral angles of 89.96 (12) and 57.

Perception of color mismatch or conspicuous marginal adaptation in extraoral prostheses with eye-tracking.

Statement Of Problem: Color matching and marginal integrity are major challenges when providing extraoral maxillofacial prostheses. Which of the color and marginal harmony features are more important for the extraoral prostheses to be inconspicuous is unclear. Studies on the perception of these prostheses with objective evaluation criteria are lacking.

The modification of nisin with homocysteine thiolactone and its effect on antimicrobial activity.

The aim of the present study is to make an important contribution to the literature by focusing on the preparation of the N-homocysteine conjugate of nisin and evaluating the effect of the N-homocysteinylation reaction on its antimicriobial activity. The modification process was monitored using both acetic acid urea polyacrylamide gel electrophoresis (AAU-PAGE) and tricine sodium dodecyl sulphate polyacrylamide gel electrophoresis (tricine SDS-PAGE). The antibacterial effectiveness of modified nisin was assessed against Staphylococcus aureus ATCC 6538, Enterococcus faecium ATCC 9097, Bacillus subtilis ATCC 6633, Lactococcus lactis ssp.

High-Resolution Plasma Metabolomics and Thiamine Status in Critically Ill Adult Patients.

Background And Aim: Thiamine (Vitamin B1) is an essential micronutrient and a co-factor for metabolic functions related to energy metabolism. We determined the association between whole blood thiamine pyrophosphate (TPP) concentrations and plasma metabolites using high resolution metabolomics in critically ill patients.

Methods: Cross-sectional study performed in Erciyes University Hospital, Kayseri, Turkey and Emory University, Atlanta, GA, USA.

Correlation of Tinnitus Severity Index and Tinnitus Handicap Inventory with Hematological Parameters in Patients with Subjective Tinnitus.

 Tinnitus etiopathogenesis is still unclear and treatment options are controversial despite current advances in medicine.  To analyze the correlation between patients' symptom scores, systemic inflammation, and trombosis biomarkers.  In this prospective study, we evaluated the degree of complaints of subjective tinnitus patients with the tinnitus severity index (TSI) and tinnitus handicap inventory (THI), and correlated these symptom scores with hematological parameters such as the neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), mean thrombocyte volume (MPV), and platelet distribution width (PDW).

Synthesis, crystal structure and Hirshfeld surface analysis of (2,2')-2,2'-(3-meth-oxy-3-phenylpropane-1,2-diyl-idene)bis-(hydrazine-1-carbo-thioamide) di-methyl-formamide monosolvate.

The overall mol-ecular configuration of the title compound, CHNOS·CHNO, is stabilized in the solid state by intra-molecular C-H⋯N, C-H⋯O, N-H⋯N and N-H⋯O inter-actions, forming (5) ring motifs. In the crystal, mol-ecules are linked to each other and solvent di-methyl-formamide mol-ecules by N-H⋯S, N-H⋯O, C-H⋯O and C-H⋯S hydrogen bonds, forming a three dimensional network. The phenyl ring of the title compound is disordered over two sites with an occupancy ratio of 0.

Crystal structure and Hirshfeld surface analysis of 4-azido-2-(3,5-di-methyl-phen-yl)-5-(4-nitro-phen-yl)-2-1,2,3-triazole.

In the title compound, CHNO, the 3,5-di-methyl-phenyl and 4-nitro-phenyl rings are inclined to the central 2-1,2,3-triazole ring by 1.80 (7) and 1.79 (7)°, respectively, and to one another by 2.