Associations Between Upper Extremity Function, Activities of Daily Living, and Functional Capacity in Patients with Heart Failure with Reduced Ejection Fraction.

Objective: Limited information is available regarding the associations between upper extremity function, activities of daily living (ADLs), and functional capacity in patients with heart failure with reduced ejection fraction (HFrEF). This study aimed to investigate the associations between upper extremity function, ADLs, and functional capacity in patients with HFrEF.

Methods: This cross-sectional study included 31 patients with HFrEF.

Causal Mediation Analysis of Foodborne Outbreaks in the United States: Serotypes and Food Vehicles.

Various serotypes have caused numerous foodborne outbreaks associated with food vehicles in different categories. This study provides evidence on the occurrence and inter-relations between serotypes and the number of deaths mediated by the number of illnesses and hospitalizations. Confirmed foodborne outbreaks of serotypes (n = 2868) that occurred between 1998 and 2021 were obtained from the Centers for Disease Control and Prevention National Outbreak Reporting System.

From Tradition to Innovation: Diverse Molecular Techniques in the Fight Against Infectious Diseases.

Infectious diseases impose a significant burden on global health systems due to high morbidity and mortality rates. According to the World Health Organization, millions die from infectious diseases annually, often due to delays in accurate diagnosis. Traditional diagnostic methods in clinical microbiology, primarily culture-based techniques, are time-consuming and may fail with hard-to-culture pathogens.

Stigma, Depression, and Attitudes Towards Seeking Psychological Help Among Nurses: The Role of Personal Stigma as an Inconsistent Mediator.

Rationale: Identifying whether perceived stigma or personal stigma more significantly affects nurses' attitudes towards seeking psychological help is essential for effectively addressing current challenges and facilitating early intervention for the well-being of nurses and their patients.

Aims And Objectives: The aim of this study was to explore the mediating roles of personal stigma and depression in the relationship between perceived stigma among nurses and their attitudes towards seeking psychological help.

Methods: The sample of this descriptive cross-sectional study consisted of 302 nurses working in a university hospital in southern Turkey, selected using the purposive sampling method, between April 1 and May 1, 2021.

Biomechanical Analysis and Solution Suggestions of Screw Replacement Scenarios in Femoral Neck Fracture Surgeries: Finite Element Method.

Objective: Despite several surgical options, there has yet to be a consensus on the best treatment for femoral neck fracture (FNF) due to higher complication rates compared to other bone fractures. This study aims to examine the possible consequences and solution suggestions of changing screws during surgery for various reasons in FNF surgical treatment from a biomechanical perspective.

Method: FNF and treatment materials were analyzed biomechanically using a package program based on the finite element method (FEM).

An electrochemical sensor integrated lab-on-a-CD system for phenylketonuria diagnostics.

Phenylketonuria (PKU) is characterized by an autosomal recessive mutation in the phenylalanine hydroxylase (PAH) gene. Impaired PAH enzyme activity leads to the accumulation of phenylalanine (Phe) and its metabolites in the bloodstream, which disrupts the central nervous system and causes psychomotor retardation. Early diagnosis of PKU is essential for timely intervention.

Evaluation of the antimicrobial and anticancer potential of a modified silver nanoparticle-impregnated carrier system.

This study aimed to develop silver nanoparticles embedded in poly(ricinoleic acid)-poly(methyl methacrylate)-poly(ethylene glycol) (AgNPsPRici-PMMA-PEG) nanoparticles (NPs) containing caffeic acid (Caff) and tetracycline hydrochloride (TCH) for treating infections and cancer in bone defects. The block copolymers were synthesised via free radical polymerisation. NPs were prepared using the solvent evaporation method and characterised by FTIR, HNMR, SEM, DSC, TGA, and DLS.

Novel Aminothiazole-Chalcone Analogs: Synthesis, Evaluation Acetylcholinesterase Activity, In Silico Analysis.

In this study, novel thiazole-chalcone analogs were synthesized, and their inhibitory effects on acetylcholinesterase (AChE) were examined. In vitro enzyme activity studies were conducted to calculate IC values, which were found to range between 2.55 and 72.

Investigation of a novel Schiff base Catena-((μ-(E)-2-((4-methoxy-2-oxidobenzylidene)ammonio)ethane-1-sulfonato potassium as a potential antibacterial agent.

Context: Schiff bases, which have intriguing properties in many areas, have been studied extensively in recent years due to their structural properties and biological activities. In this research, a novel water-soluble Schiff base complex, Catena-((μ-(E)-2-((4-methoxy-2-oxidobenzylidene) ammonio) ethane-1-sulfonato potassium, CHKNOS (CMOAESP), was synthesized by a one-step condensation reaction of 2-hydroxy-4-methoxy benzaldehyde and taurine with the yield of 65%, 0.333 g.

DNA protection, molecular docking, molecular dynamic, enzyme inhibition, and kinetics studies of apigenin isolated from Hedge & Lamond by bioactivity-guided fractionation.

Plant-derived bioactive substances have demonstrated significant qualities that suggest they may be crucial in preventing various chronic diseases. Flavonoids, which include apigenin, are the biggest group of polyphenols. In our study, we aimed to obtain the methanol-chloroform (1:1) extract from the aerial parts of Hedge & Lamond and purify the apigenin using bioactivity-guided isolation to separate the active fraction.

Predictors of Traumatization Among Humanitarian Aid Workers Working With Refugees and Asylum Seekers in Türkiye.

Refugees and asylum-seekers flee their countries due to conflict, violence or persecution and seek safety in another country. Professionals working with refugees in host countries are being exposed to the narratives of their traumatic experiences, an important risk factor for vicarious posttraumatic stress. The current study examined predictors for traumatic stress in humanitarian aid workers working with refugees and asylum seekers in Türkiye.

The power new XLindley distribution: Statistical inference, fuzzy reliability, and applications.

This paper introduces the power new XLindley (PNXL) distribution, a novel two-parameter distribution derived using the power transformation method applied to the XLindley distribution. We thoroughly explore the structural properties of the PNXL distribution, including the th moment about the origin, moment generating function, survival rate function, distribution function, hazard rate function, skewness, kurtosis, and coefficient of variation. Additionally, we derive the quantile function, fuzzy reliability, reliability measures, stochastic ordering, and actuarial measures for this new distribution.

Evaluation of Depression and Perceived Voice Handicap Through Self-Report in Individuals With Alzheimer's Disease.

Objectives: To assess depression and perception of vocal handicap in individuals with and without early-stage Alzheimer's disease (AD) using a self-report method.

Methods: It was conducted between April 2024 and June 2024 with individuals who visited the Internal Medicine Clinics of Çankırı State Hospital, including those with AD (study group: n = 41) and those without AD (with normal cognitive levels) (control group: n = 50). 41.

Increased Femoral Neck Anteversion is Prevalent in Male Elite Youth Soccer Players with Chronic Ankle Instability.

Purpose: The aim of this study was to compare femoral neck anteversion (FNA) and determine the prevalence of increased FNA in male elite youth soccer players with and without chronic ankle instability (CAI). Secondary aims were to evaluate the utility of FNA in predicting CAI and compare ankle and hip muscle strength in the two groups.

Materials And Methods: The study included a total of 44 male elite youth soccer players, 22 with CAI (mean age 16.

Nurses' Perceptions of Their Professional Autonomy in Nonpharmacologic Pain Management: A Qualitative Study.

Purpose: The aim was to examine nurses' experiences and opinions regarding using their professional autonomy in nonpharmacologic pain management.

Design: A qualitative descriptive approach was used in the study.

Methods: The study was conducted in the acute care services of a public hospital between December 10, 2022, and March 2023.

Boswellia serrata Powder Regimen Provides Significant Protection Against Renal Damage and Blood Imbalances in Diabetic Rats.

Diabetic kidney disease affects approximately one-third of diabetes patients. Hyperglycemia and oxidative stress contribute to this condition. Boswellia serrata gum resin is known for its antioxidant properties and potential in managing diabetic complications, though its nephroprotective effects are not well documented.

Emotions, coping and psychological flexibility in earthquake survivors: a cross-sectional study.

Earthquakes may play a role in the development of several psychological distresses or psychopathologies. Nevertheless, protective factors such as positive emotions, psychological flexibility, and coping mechanisms may be helpful for earthquake survivors in coping. On the other hand, the role of both positive and negative emotions of earthquake survivors in psychological flexibility and coping remains elusive.

Assessing regional variation of individual-tree diameter increment of Crimean pine and investigating interactive effect of competition and climate on this species.

Nowadays, many forests are intensely exposed to the adverse effects of climate change such as drought. To increase the resilience of the forests against climate change, prescribing appropriate silvicultural treatments is of great importance. At this point, closely scrutinizing the simultaneous effects of competition and climate on the forests has become a very important issue.

The influence of unstable surfaces on ankle muscle activation during functional exercises.

Background: The study aims to compare how 3 balance platform designs affect ankle muscle activation during various functional exercises, all performed on the dominant limb.

Methods: Fifteen healthy, active participants performed single-leg stance, single-leg squat, and forward lunge on BOSU® Ball, wobble board, stability trainer, and flat ground. Surface electromyography was used to measure Peroneus Longus, Tibialis Anterior, Gastrocnemius, and Soleus activation during these exercises on different platforms and flat ground.

Does reformer pilates exercise improve cognitive functions in sedentary women? A randomized controlled study.

Background: The reformer is an apparatus on which to perform the foot work and the body in a comfortable, nonweight-bearing supine position and keeps the muscles in balance. The aim of this randomized controlled and single-center study was to investigate the effect of reformer Pilates exercises on cognitive functions in sedentary women.

Methods: A total of 44 sedentary women aged between 24 and 50 were randomized into two groups.

Comparison of Perceived Fatherhood and Self-Efficacy Across Generations and Gender.

A quality father-child relationship is important for the child's social and emotional development, which may affect one's self-efficacy in the future. Research showed that fatherhood attitudes change over time. In the current study, individuals in generations X, Y and Z evaluated their relationships with their fathers retrospectively and their own general self-efficacy and it was examined whether participants' perceived fatherhood attitudes and general self-efficacy levels varied according to their gender and generation they were in.