2 results match your criteria: "Canada K1Y 4E9. tcooi@ottawahospital.on.ca[Affiliation]"

Effect of fibrates on postprandial remnant-like particles in patients with combined hyperlipidemia.

Atherosclerosis

February 2004

Metabolism and Hormone Laboratory, Division of Endocrinology and Metabolism, Department of Medicine, Ottawa Hospital, University of Ottawa, Civic Campus, 1053 Carling Avenue, Ottawa, Ont., Canada K1Y 4E9.

We have investigated the effect of standard doses of two fibrates, gemfibrozil and fenofibrate, on fasting and postprandial remnant-like particles (RLP) in subjects with combined hyperlipidemia. Forty-eight subjects participated; of these, 14 underwent a Vitamin A-fat loading test before and after 6 months of treatment with gemfibrozil (n = 8) and fenofibrate (n = 6). Blood was drawn every 2h for 12h after the test meal.

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Postprandial remnant-like lipoproteins in hypertriglyceridemia.

J Clin Endocrinol Metab

July 2001

Metabolism and Hormone Laboratory, Department of Laboratory Medicine, Ottawa Hospital-Civic Campus, University of Ottawa, Ottawa, Ontario, Canada K1Y 4E9.

It has been proposed that remnants of chylomicrons and very-low-density lipoproteins (VLDL) are atherogenic. We have used an immunochemical method to isolate remnant-like particles (RLP) and measured them in terms of their cholesterol and triglycerides (TG). RLP consist of apoB-48-containing triglyceride-rich lipoproteins and remnant-like VLDL containing apoB-100.

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