Magnetic field probe-based co-simulation method for irregular volume-type inductively coupled wireless MRI radiofrequency coils.

Background: Inductively coupled wireless coils are increasingly used in MRI due to their cost-effectiveness and simplicity, eliminating the need for expensive components like preamplifiers, baluns, coil plugs, and coil ID circuits. Existing tools for predicting component values and electromagnetic (EM) fields are primarily designed for cylindrical volume coils, making them inadequate for irregular volume-type wireless coils.

Purpose: The aim of this study is to introduce and validate a novel magnetic (H-) field probe-based co-simulation method to accurately predict capacitance values and EM fields for irregular volume-type wireless coils, thereby addressing the limitations of current prediction tools.

Bidirectional Associations Between Parent-Child Conflict and Child and Adolescent Mental Health.

Objective: To estimate the longitudinal bidirectional association between parent-child conflict and child externalizing and internalizing symptoms from the preschool years through adolescence.

Method: A nationally representative longitudinal study recruited 11,134 children at birth and followed them from December 2010 through June 2022. Primary caregivers completed validated measures at each follow-up, yielding data on parent-child conflict and child symptoms at ages 3, 5, 7, 9, and 13 years.

Impact of interventions on mpox transmission during the 2022 outbreak in Canada: a mathematical modeling study of three different cities.

Objectives: The global mpox (clade II) outbreak of 2022 primarily affected gay, bisexual, and other men who have sex with men (GBM) and was met with swift community and public health responses. We aimed to estimate the relative impact of changes in sexual behaviours, contact tracing/isolation, and first-dose vaccination on transmission in Canadian cities.

Methods: We estimated changes in sexual behaviours during the outbreak using 2022 data from the Engage Cohort Study which recruited self-identified GBM in Montréal, Toronto, and Vancouver (n=1,445).

Development of a health equity tool in resuscitation sciences and application to current research in extracorporeal cardiopulmonary resuscitation for cardiac arrest.

Background: Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly used for adults with cardiac arrest (CA) refractory to Advanced Cardiovascular Life Support (ACLS). Concerns exist that adding ECPR could worsen health inequities, defined as differences in health outcomes that are unfair or unjust. Current guidelines do not explicitly address this issue.

The Role of Sex and Gender in Acute Kidney Injury - Consensus Statements from the 33 Acute Disease Quality Initiative.

Sex differences exist in acute kidney injury (AKI), and the role that sex and gender play along the AKI care continuum remains unclear. The 33 Acute Disease Quality Initiative meeting evaluated available data on the role of sex and gender in AKI and identified knowledge gaps. Data from experimental models, pathophysiology, epidemiology, clinical care, gender, social determinants of health, education, and advocacy were reviewed.

Emotions & Heart:Exploring the Impact of Negative Emotions on Cardiovascular Health.

Negative emotions can have a significant impact on individuals, which then influences their cardiovascular system. However, the underlying pathophysiological mechanisms and clinical implications of this association remain inadequately defined. A narrative review of pertinent literature was conducted to examine the pathophysiology, clinical manifestations, and treatment related to the interplay between emotions and conditions such as takotsubo cardiomyopathy, atherosclerosis, acute plaque rupture, and cardiac arrhythmias.

Comparison of Acute and Protracted Gamma Irradiation Effects During Perinatal Development in Beagle Dogs.

Ionizing radiation exposure during perinatal development can produce various biological effects on the developing offspring. These effects are dependent on a number of factors, including total dose, dose rate and the developmental processes occurring at the time of irradiation. The present study conducted an analysis of historical radiobiological archived data involving 60Co-gamma irradiation of beagle dogs at specific periods of prenatal or postnatal development.

Semaglutide in obesity-related heart failure with preserved ejection fraction and type 2 diabetes across baseline HbA levels (STEP-HFpEF DM): a prespecified analysis of heart failure and metabolic outcomes from a randomised, placebo-controlled trial.

Background: About half of patients with heart failure with mildly reduced or preserved ejection fraction (HFpEF) have type 2 diabetes. In the STEP-HFpEF DM trial of adults with obesity-related HFpEF and type 2 diabetes, subcutaneous once weekly semaglutide 2·4 mg conferred improvements in heart failure-related symptoms and physical limitations, bodyweight, and other heart failure outcomes. We aimed to determine whether these effects of semaglutide differ according to baseline HbA.

Assessment of radioactivity in soil samples from Wolaita Sodo town, Ethiopia: implications for environmental and public health.

This study assesses the activity concentrations of the radionuclides 238U, 232Th, and 40K in soil samples collected from Wolaita Sodo town, located in the Southern Nations, Nationalities, and Peoples' (SNNP) Region, Ethiopia. A gamma-ray spectrometer equipped with a NaI(Tl) detector was used for the measurements. The concentrations of 238U, 232Th, and 40K varied from 3.

Effects of lifetime feeding of hydrolyzed yeast to broiler breeders on egg production, quality, and hatchling attributes.

The effects of lifetime feeding of hydrolyzed yeast (HY) to broiler breeders (BB) on egg production, egg quality, and hatchling attributes were investigated. The birds were selected from two groups reared on diets with or without 0.05 % HY from hatch.

Review of the potential for selenium remobilization in semi-passive treatment systems of mine impacted waters.

Biological semi-passive mine water treatment technologies are used in the mining industry as an alternative to or in conjunction with active treatment systems to remediate mine impacted water (MIW) containing nitrate and selenium oxyanions such as selenate and selenite. In semi-passive biological treatment systems, MIW is pumped through a saturated, porous media (either a gravel bed or waste rock) which provides ample surface area for biofilm growth and the creation of anoxic, subaqueous environments. Additional nutrients and carbon sources are pumped into the system to encourage the growth of microbes that biochemically reduce selenate and selenite to insoluble reduced Se species such as selenium nanoparticles (SeNP) by respiring selenate and selenite.

National scale assessment of the occurrence and risk of trace organic contaminants in Canadian Lake sediments.

In Canada studies on the presence of trace organic contaminants (TrOCs) such as pharmaceuticals, personal care products, pesticides and flame retardants in lakes have primarily focused on the water column at localized scales. To address this gap, the occurrence of 44 TrOCs, representative of various types of human activities, was investigated in surface sediments (0-2 cm) from 193 lakes across Canada. A total of 28 targeted TrOCs were detected, with 99.

Validation of the Portuguese version of the Movement Disorder Society non-motor rating scale (MDS-NMS) in Parkinson's disease.

Background: The Movement Disorder Society Non-Motor Rating Scale (MDS-NMS) serves as a comprehensive clinical assessment tool for non-motor symptoms in Parkinson's disease (PD) OBJECTIVES: This study aims to validate the Portuguese version of the MDS-NMS, addressing the critical need for culturally adapted rating scales in Portuguese-speaking populations.

Methods: This multicenter, cross-sectional study engaged native Portuguese-speaking PD patients from 16 Movement Disorders Centers across Portugal and Brazil. We conducted a meticulous translation process into Portuguese, including forward-backward translation and cognitive pretesting.

Vibro-tactile stimulation of the neck induces head righting in people with cervical dystonia.

Introduction: Cervical dystonia (CD) is characterized by involuntary neck muscle spasms that lead to abnormal head movements or postures. It is associated with somatosensory (tactile and proprioceptive) dysfunction. Here we tested whether vibro-tactile stimulation (VTS) of the cervical muscles constitutes a non-invasive form of neuromodulation of the somatosensory system that can provide temporary symptom relief for people with CD.

Effects of various modes of forward and backward cycling on neuro-biomechanical outcomes in individuals after stroke and healthy controls.

Background: Stationary cycling is recommended for post-stroke rehabilitation. This study assessed neuro-biomechanical outcomes of forward and backward cycling in three different modes: free-pedalling, constant speed (30 RPM) and constant resistance (5 or 10 Nm) in healthy controls and individuals after stroke.

Methods: Ten individuals after stroke and 10 healthy controls performed 60s cycling trials in different directions and modes on a semi-recumbent bike prototype.

Eco-friendly synthesis of Arabinoxylan-Catechin conjugates: Enhanced functional and antioxidant properties via cold plasma and ultrasonic methods.

Arabinoxylan-catechin complexes were synthesized using two eco-friendly methods: cold plasma and ultrasonic treatments. Their physicochemical, structural and functional properties were evaluated. Cold plasma and ultrasonic treatments did not significantly alter the molecular structure of arabinoxylan, although a decrease Mw was noticed.

Pembrolizumab in microsatellite instability-high/mismatch repair deficient (MSI-H/dMMR) and non-MSI-H/non-dMMR advanced endometrial cancer: Phase 2 KEYNOTE-158 study results.

Objective: We report updated results with longer follow-up in patients with MSI-H/dMMR endometrial cancer (EC) in cohort D (advanced EC of any MSI/dMMR status) and cohort K (any MSI-H/dMMR advanced solid tumor, except colorectal) of the phase 2 KEYNOTE-158 study (NCT02628067) and the first results from patients with non-MSI-H/non-dMMR advanced EC (cohort D).

Methods: Patients received pembrolizumab 200 mg Q3W for ≥35 cycles. The primary endpoint was objective response rate (ORR) per RECIST v1.

Iodine intakes of pregnant females from Québec, Canada.

Background: Adequate maternal iodine intake is important for fetal brain development. Based on iodine intakes of non-pregnant females of reproductive age from the Canadian Health Measures Survey (2016 -2017) it can be extrapolated that most pregnant females in Canada will not meet iodine requirements without supplementation.

Objectives: To assess iodine intakes of 500 pregnant, nulliparous females from Québec, Canada and report on use of multivitamin/mineral (MVM) supplements and coverage of iodized salt.

Boat noise reduces vocalization rate and alters vocal characteristics in wild plainfin midshipman fish.

Anthropogenic noise pollution has been accelerating at an alarming rate, greatly altering aquatic soundscapes. Animals use various mechanisms to avoid acoustic masking in noisy environments, including altering calling rates or the frequency (pitch) of their vocalizations or increasing the amplitude (loudness) of their vocalizations (i.e.

A multimodal deep learning model for cervical pre-cancers and cancers prediction: Development and internal validation study.

Background: The current cervical cancer screening and diagnosis have limitations due to their subjectivity and lack of reproducibility. We describe the development of a deep learning (DL)-based diagnostic risk prediction model and evaluate its potential for clinical impact.

Method: We developed and internally validated a DL model which accommodates both clinical data and colposcopy images in predicting the patients CIN2+ status using a retrospective cohort of 6356 cases of LEEP-conization/cone-biopsy (gold-standard diagnosis) following an abnormal screening result.

Exposure experiments and machine learning revealed that personal care products can significantly increase transdermal exposure of SVOCs from the environment.

We investigated the impacts of personal care products (PCPs) on dermal exposure to semi-volatile organic compounds (SVOCs), including phthalates, organophosphate esters, polycyclic aromatic hydrocarbons (PAHs), ultraviolet filters, and p-phenylenediamines, through an experiment from volunteers, explored the impact mechanisms of PCP ingredients on dermal exposure, and predicted the PCP effects on SVOC concentrations in human serum using machine learning. After applying PCPs, namely lotion, baby oil, sunscreen, and blemish balm, the dermal adsorption of SVOCs increased significantly by 1.63 ± 0.

Associations and potential epigenetic changes between air pollution and osteoarthritis risk and survival: Insights from a prospective cohort study.

Background: The influence of air pollution on osteoarthritis (OA) remains underexplored.

Methods: We conducted a prospective cohort study in the UK Biobank, estimating exposure levels of particulate matter (PM, PM, PM) nitrogen oxides (NO, NO), and air pollutants exposure score (APES). Cox models assessed associations between air pollution exposure and OA incidence, joint replacement, and survival.

Evaluation and Management of Congenital Cytomegalovirus Infection.

The purpose of this review is to serve as an update on congenital cytomegalovirus (CMV) evaluation and management for obstetrician-gynecologists and to provide a framework for counseling birthing people at risk for or diagnosed with a primary CMV infection or reactivation or reinfection during pregnancy. A DNA virus, CMV is the most common congenital viral infection and the most common cause of nongenetic childhood hearing loss in the United States. The risk of congenital CMV infection from transplacental viral transfer depends on the gestational age at the time of maternal infection and whether the infection is primary or nonprimary.

Microbial communities in Hudson Strait amidst rapid environmental changes.

Climate change is rapidly altering Arctic marine environments, leading to warmer waters, increased river discharge, and accelerated sea ice melt. The Hudson Bay Marine System (HBMS) experiences the fastest rate of sea ice loss in the Canadian North resulting in a prolonged open water season during the summer months. We examined microbial communities in the Hudson Strait using high throughput 16s rRNA gene sequencing during the peak of summer, in which the bay was almost completely ice-free, and air temperatures were high.