Dissociation of adsorbates electronic energy transfer from aromatic thin films.

Photofragment translational spectroscopy has been used to characterize the energetics and the cross sections for photodissociation of CHI and CFI adsorbed on thin films of a variety of aromatic molecules, initiated by near-UV light. Thin films (nominally 10 monolayers) of benzene, five substituted benzenes and two naphthalenes have been employed to study systematic changes in the photochemical activity. Illumination of these systems with 248 nm light is found to result in a dissociation process for the CHI and CFI mediated by initial absorption in the aromatic thin film, followed by electronic energy transfer (EET) to the dissociating species.

US state death rates: Structural equation modeling of Big Five personality, socioeconomic status, and health risk factors.

Structural equation modeling (SEM) tested the of a model with neuroticism, openness to experience, socioeconomic status (SES), and race as predictors of a composite of six health risks and age-adjusted all-cause mortality in 2020 using the 48 contiguous American states as analytic units. In the final model, neuroticism, openness, and SES accounted for 80% of the health risk composite variance. These three variables and composite health risk accounted for 85% of the death rate variance.

Brain serotonin, oxytocin, and their interaction: Relevance for eating disorders.

Introduction: Eating disorders are characterized by maladaptive eating behaviors and preoccupations around body shape, weight, and eating. The serotonin system has been among the most widely studied neurobiological factors in relation to eating disorders. Recent research also highlighted the role of oxytocin.

Marginal response of non-structural carbohydrates and increased biomass in a dominant shrub (Dasiphora fruticosa) to water table decline in a minerotrophic peatland.

Assessing how dominant peatland species, such as Dasiphora fruticosa, adapt to water table decline is crucial to advance understanding of their growth and survival strategies. Currently, most studies have primarily focused on their growth and biomass, with limited knowledge on the response of non-structural carbohydrates (NSCs) and physiological adaptations of these woody plants under long-term drainage. This study assessed the response of photosynthesis and transpiration rates, biomass, and NSC concentrations (including soluble sugars and starch) in the leaves, stems, and roots of D.

APP lysine 612 lactylation ameliorates amyloid pathology and memory decline in Alzheimer's disease.

Posttranslational modification (PTM) of the amyloid precursor protein (APP) plays a critical role in Alzheimer's disease (AD). Recent evidence reveals that lactylation modification, as a novel PTM, is implicated in the occurrence and development of AD. However, whether and how APP lactylation contributes to both the pathogenesis and cognitive function in AD remains unknown.

Cardiac fibroblast BAG3 regulates TGFBR2 signaling and fibrosis in dilated cardiomyopathy.

Loss of Bcl2-associated athanogene 3 (BAG3) is associated with dilated cardiomyopathy (DCM). BAG3 regulates sarcomere protein turnover in cardiomyocytes; however, the function of BAG3 in other cardiac cell types is understudied. In this study, we used an isogenic pair of BAG3-knockout and wild-type human induced pluripotent stem cells (hiPSCs) to interrogate the role of BAG3 in hiPSC-derived cardiac fibroblasts (CFs).

Lubiprostone Reduces Fat Content on MRI-PDFF in Patients With MASLD: A 48-Week Randomised Controlled Trial.

Background And Aims: The laxative lubiprostone has been shown to decrease intestinal permeability. We aimed to assess the safety and efficacy of lubiprostone administered for 48 weeks in patients with metabolic dysfunction-associated steatotic liver disease (MASLD).

Approach And Results: A randomised placebo-controlled trial was conducted in a specialised MASLD outpatient clinic at the National Hepatology and Tropical Medicine Research Institute, Cairo, Egypt.

Compliance With Routine Health Checkup Visits Among California-Based Minority Men: A Survey Study.

The literature on health care disparities among U.S. minority men remains limited, and post-pandemic changes in the health care delivery system may uniquely affect this population.

The Prevalence of Physical Intimate Partner Violence During Pregnancy and the Postpartum Period: A Systematic Review With Implications for Probable Violence-Caused Brain Injury Among Child Bearers.

Intimate partner violence (IPV) persists as a cause of short-term, long-term, and chronic health consequences. The elevated risk of IPV during pregnancy and the postpartum period (P-IPV) is commonly attributed to increased demands for child bearers and intimate partners. P-IPV may impact the health of the child bearer, developing fetus, and post-birth child.

Evaluation of the implementation of governmental policies and actions to create healthy food environments in Burkina Faso.

Objective: The creation of a healthy food environment is highly dependent on the policies that governments choose to implement. The objective of this study is to compare the level of implementation of current public policies aimed at creating healthy food environments in Burkina Faso with international good practice indicators.

Design: This evaluation was carried out using the Food-EPI tool.

Artificial Intelligence and Machine Learning in Preeclampsia.

Preeclampsia is a multisystem hypertensive disorder that manifests itself after 20 weeks of pregnancy, along with proteinuria. The pathophysiology of preeclampsia is incompletely understood. Artificial intelligence, especially machine learning with its capability to identify patterns in complex data, has the potential to revolutionize preeclampsia research.

Sex-Based Differences in Endovascular Thrombectomy Outcomes for Large Ischemic Stroke: A SELECT2 Subanalysis.

Background: Several social and biological factors are shown to differentially affect stroke outcomes between men and women. We evaluated whether clinical outcomes and endovascular thrombectomy (EVT) treatment effects differed between the sexes in patients presenting with large ischemic stroke.

Methods: The SELECT2 trial (A Randomized Controlled Trial to Optimize Patient's Selection for Endovascular Treatment in Acute Ischemic Stroke) was a randomized controlled trial assessing the efficacy and safety of EVT in patients with large strokes across the United States, Canada, Europe, Australia, and New Zealand between October 2019 and September 2022.

Gestational diabetes mellitus and subsequent cardiovascular disease in a period of rising diagnoses: Cohort study.

Introduction: Evidence suggests that gestational diabetes mellitus (GDM) is associated with subsequent cardiovascular disease; however, it is unclear what impact changes in screening and diagnostic criteria have had on the association of GDM with long-term outcomes such as cardiovascular disease. The purpose of this study was to determine the association between GDM and subsequent cardiovascular disease during a period of rising gestational diabetes diagnosis in England. Specifically, associations were compared before and after 2008, when national guidelines supporting risk factor-based screening were introduced.

Delayed Postoperative Radiotherapy in Head & Neck Cancers-A Systematic Review and Meta-Analysis.

Objectives: To evaluate the impact of delayed postoperative radiotherapy (PORT) on overall survival (OS) in patients with head and neck cancers (HNC).

Data Sources: A systematic review and meta-analysis were conducted by searching MEDLINE, Embase, CENTRAL, Web of Science, and CINAHL databases.

Review Methods: Studies assessing the impact of delayed PORT in adult HNC patients were included.

YUTO MMS: A comprehensive SLAM dataset for urban mobile mapping with tilted LiDAR and panoramic camera integration.

The York University Teledyne Optech (YUTO) Mobile Mapping System (MMS) Dataset, encompassing four sequences totaling 20.1 km, was thoroughly assembled through two data collection expeditions on August 12, 2020, and June 21, 2019. Acquisitions were performed using a uniquely equipped vehicle, fortified with a panoramic camera, a tilted LiDAR, a Global Positioning System (GPS), and an Inertial Measurement Unit (IMU), journeying through two strategic locations: the York University Keele Campus in Toronto and the Teledyne Optech headquarters in City of Vaughan, Canada.

Positioning and preparation errors impacting dental panoramic radiographs in patients with mixed dentition.

Purpose: This study aimed to evaluate the quality of clinically indicated digital dental panoramic radiographs (DPRs) of children with mixed dentition. Despite the likely widespread use of this modality, recent research detailing errors on DPRs is scarce.

Materials And Methods: A consecutive case series was performed, including 178 DPRs from patients aged 6 to 12 years.

Apolipoprotein E dysfunction in Alzheimer's disease: a study on miRNA regulation, glial markers, and amyloid pathology.

Introduction: Apolipoprotein E (ApoE) plays a crucial role in lipid homeostasis, predominantly expressed in astrocytes and to a lesser extent in microglia within the central nervous system (CNS). While the allele is the strongest genetic risk factor for late-onset Alzheimer's disease (AD), its precise role in AD pathogenesis remains elusive. -knockout (-ko) mice, mice expressing human , and human carriers exhibit similar deficits in lipid metabolism, cognitive and behavioral functions, and neurodegeneration.

An Estimate of Wolverine Density for the Canadian Province of Alberta.

Wolverines () are a circumboreal species that has experienced substantial range reduction worldwide. In Canada, the wolverine has been extirpated entirely from the east, and from prairie regions in the west. The province of Alberta holds the south-central portion of wolverines' Canadian range, and there they have been designated as since 2001 due to a historical lack of information.

Metabolomics survey of uropathogenic bacteria in human urine.

Introduction: Urinary tract infections (UTIs) are one of the most prevalent infections in North America and are caused by a diverse range of bacterial species. Although uropathogenesis has been studied extensively in the context of macromolecular interactions, the degree to which metabolism may contribute to infection is unclear. Currently, most of what is known about the metabolic capacity of uropathogens has been derived from genomics, genetic knockout studies or transcriptomic analyses.

The fungal gut microbiota in pediatric-onset multiple sclerosis.

Evidence suggests that the gut microbiome may play a role in multiple sclerosis (MS). However, the majority of the studies have focused on gut bacterial communities; none have examined the fungal microbiota (mycobiota) in persons with pediatric-onset multiple sclerosis (POMS). We examined the gut mycobiota in persons with and without POMS through a cross-sectional examination of the gut mycobiota from 46 participants' stool samples (three groups: 18 POMS, 13 acquired monophasic demyelinating syndromes [monoADS], and 15 unaffected controls).

Evaluating the 3-month post-intervention impact of a supportive text message program on mental health outcomes during the 2023 wildfires in Alberta and Nova Scotia, Canada.

Background: Individuals exposed to wildfires are at risk of developing adverse mental health conditions in the months following the event. Receiving supportive text interventions during and after a wildfire event can have a significant impact on reducing mental health conditions over time.

Objectives: The study aimed to assess the effectiveness of a supportive text message intervention service in reducing the severity and prevalence of psychological conditions 3 months following the 2023 wildfires in Alberta and Nova Scotia, two regions heavily affected by these natural disasters.

Use of multi-modelling methods to inform conservation and reintroductions of pine marten in Britain.

The successful onset of recovery of the European pine marten () in some parts of Britain through range expansion and, more recently translocation for reintroductions, has resulted in a strong interest in reintroduction projects throughout the country. However, the geographic scope and conservation goals of these initiatives are often local and lack consideration of how they fit within the wider context of national-scale pine marten conservation. Here, we aim to maximize conservation benefit strategically at a national level by developing a simple, transparent, and transferable framework based on landscape modelling methods and spatially explicit population viability analyses.