Gold nanoclusters as prospective carriers and detectors of pramipexole.

Pramipexole (PPX) is known in the treatment of Parkinson's disease and restless legs syndrome. We carried out a theoretical investigation on pramipexole-Au cluster interactions for the applications of drug delivery and detection. Three Au clusters with sizes = 6, 8 and 20 were used as reactant models to simulate the metallic nanostructured surfaces.