Information Gradient among Nucleotide Sequences of Essential RNAs from an Evolutionary Perspective.

We hypothesize that the first ancestral "protocell" molecular structures, i.e., the first RNAs and peptides that gradually transformed into real cells once the Earth had cooled sufficiently for organic molecules to appear, have left traces in the RNAs and the genes in present cells.

Brain Tumor Radiogenomic Classification of O-Methylguanine-DNA Methyltransferase Promoter Methylation in Malignant Gliomas-Based Transfer Learning.

Artificial Intelligence (AI) is the subject of a challenge and attention in the field of oncology and raises many promises for preventive diagnosis, but also fears, some of which are based on highly speculative visions for the classification and detection of tumors. A brain tumor that is malignant is a life-threatening disorder. Glioblastoma is the most prevalent kind of adult brain cancer and the 1 with the poorest prognosis, with a median survival time of less than a year.

Challenges and solutions for the integrated recovery room planning and scheduling problem during COVID-19 pandemic.

This study presents an efficient solution for the integrated recovery room planning and scheduling problem (IRRPSP). The complexity of the IRRPSP is caused by several sources. The problem combines the assignment of patients to recovery rooms and the scheduling of caregivers over a short-term planning horizon.

GIS-Facilitated Seed Germination and Multifaceted Evaluation of the Endangered Trab. (Pinaceae) Enabling Conservation and Sustainable Exploitation.

In the frame of the sustainable use of neglected and underutilized phytogenetic resources, and along with numerous studies in spp. due to the innate conservation value of fir forests, this research focused on the Moroccan endemic fir, The aim was triple-fold: to assess its potential and dynamics in economic sectors for sustainable exploitation; to determine the ecological conditions in which the species naturally thrives; and to find the appropriate requirements for its successful seed germination. We sourced multifaceted evaluations for three economic sectors performed in three levels, using 48 attributes and eight criteria from previous studies of our own, and the relevant species-specific assessments are overviewed herein in detail.

Eco-Geographical, Morphological and Molecular Characterization of a Collection of the Perennial Endemic Species (Murb.) A.W. Hill (Fabaceae) from Tunisia.

In order to characterize and conserve the endemic pastoral species , many prospecting missions were carried out in mountainous regions of the Tunisian ridge. Twenty-seven eco-geographical and morphological traits were studied for six accessions and followed by molecular analysis using seven Simple Sequence Repeat (SSR). Only five markers were polymorphic and reproductible in the six populations.

Agro-Alimentary Potential of the Neglected and Underutilized Local Endemic Plants of Crete (Greece), Rif-Mediterranean Coast of Morocco and Tunisia: Perspectives and Challenges.

The neglected and underutilized plants (NUPs) could become alternative food sources in the agro-alimentary sector, enriching human and animal diets, offering the opportunity for sustainable exploitation, resilience to climate change, and production with resistance to pests and diseases. In the Mediterranean countries, these valuable resources are threatened by climate change, overexploitation, and/or monoculture. In this framework, we evaluated 399 local endemic NUPs of Crete (Greece), the Mediterranean coast, Rif of Morocco, and Tunisia, regarding their agro-alimentary potential, and assessed their feasibility and readiness timescale for sustainable exploitation with own previously published methodology.

Bioactivities and phenolic composition of Maire and Brullo & Erben (Plumbaginaceae): two Tunisian strict endemic plants.

genus is traditionally used in North Africa for disease treatment and in cosmetic. This study investigates for the first time the antioxidant, anti-inflammatory and enzyme inhibitory activities of two Tunisian endemic plants, and . Analysis of phenolic compounds was carried out by using RP-HPLC.