4 results match your criteria: "Campus Bielefeld Hospital[Affiliation]"
Integrating federated learning for improved counterfactual explanations in clinical decision support systems for sepsis therapy.
Artif Intell Med
November 2024
Department of Anaesthesiology, Intensive Care, Emergency Medicine, Transfusion Medicine and Pain Therapy, University Hospital OWL, Campus Bielefeld-Bethel, Protestant Hospital of the Bethel Foundation, Burgsteig 13, Bielefeld, 33617, Germany. Electronic address:
In recent years, we have witnessed both artificial intelligence obtaining remarkable results in clinical decision support systems (CDSSs) and explainable artificial intelligence (XAI) improving the interpretability of these models. In turn, this fosters the adoption by medical personnel and improves trustworthiness of CDSSs. Among others, counterfactual explanations prove to be one such XAI technique particularly suitable for the healthcare domain due to its ease of interpretation, even for less technically proficient staff.
View Article and Find Full Text PDFVirus variant-specific clinical performance of a SARS-CoV-2 rapid antigen test with focus on Omicron variants of concern.
Clin Microbiol Infect
August 2023
Institute of Laboratory Medicine, Microbiology and Transfusion Medicine, Campus Bielefeld Hospital, University Hospital OWL, Bielefeld, Germany. Electronic address:
Article Synopsis
- Antigen rapid diagnostic tests (Ag-RDTs) provide a faster and cheaper alternative to RT-PCR for diagnosing SARS-CoV-2, but their reliability with Omicron variants is unclear.
- A study comparing Ag-RDT performance to RT-PCR indicated an overall sensitivity of 63.7% and highlighted that sensitivity is significantly lower for Omicron variants (64.1%) compared to wild-type SARS-CoV-2 (70.0%).
- Despite decreased sensitivity for lower viral loads and Omicron variants, Ag-RDTs remain a vital tool for quick and accessible SARS-CoV-2 detection in clinical settings.
Performance of the Sofia SARS-CoV-2 rapid antigen test as frontline test in a university hospital, Germany.
Diagn Microbiol Infect Dis
May 2022
Institute of Virology, University Medical Centre and Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address:
The rapid and reliable detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is of high importance for individual patient care and hospital infection prevention. We aimed to evaluate the performance of the Sofia SARS-CoV-2 antigen rapid diagnostic test (Ag-RDT) in comparison to real-time reverse-transcription polymerase chain reaction (RT-PCR). We conducted a prospective, monocentric cross-sectional study in an emergency department of a German university hospital from November 2020 to March 2021.
View Article and Find Full Text PDFReal-life evaluation of the Sofia SARS-CoV-2 antigen assay in a large tertiary care hospital.
J Clin Virol
July 2021
Institute of Laboratory Medicine, Microbiology and Transfusion Medicine, University Hospital OWL, Campus Bielefeld Hospital, Teutoburger Str. 50, 33604 Bielefeld, Germany. Electronic address: