Preoperative estimates of glomerular filtration rate as predictors of outcome after surgery: a systematic review and meta-analysis.

Background: Kidney dysfunction is a strong determinant of prognosis in many settings.

Methods: A systematic review and meta-analysis was undertaken to explore the relationship between estimated glomerular filtration rate (eGFR) and adverse outcomes after surgery. Cohort studies reporting the relationship between eGFR and major outcomes, including all-cause mortality, major adverse cardiovascular events, and acute kidney injury after cardiac or noncardiac surgery, were included.