16,936 results match your criteria: "Cameroon; Institute of Medical Research and Studies of Medicinal Plant IMPM[Affiliation]"

Populations of forest trees exhibit large temporal fluctuations, but little is known about the synchrony of these fluctuations across space, including their sign, magnitude, causes and characteristic scales. These have important implications for metapopulation persistence and theoretical community ecology. Using data from permanent forest plots spanning local, regional and global spatial scales, we measured spatial synchrony in tree population growth rates over sub-decadal and decadal timescales and explored the relationship of synchrony to geographical distance.

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The present study investigated the cytotoxic prospects of isolated compounds from against leukemia, using computational tools. Comprehensive literature searches revealed only buchaninoside, mutangin, methyl 3β-acetoxy-11α, 19α, 28-trihydroxyurs-12-en-23-oic acid, 3β, 11α, 19α-trihydroxyurs-12-en-23, 28-dioic acid, 3β-acetoxy-19α, 24, 28-trihydroxyurs-12-ene, 3-oxo-19α,28-dihydroxyurs-12-en-24-oic acid, and elabunin have been isolated from . The compounds were subjected to Density Functional Theory (DFT) and Molecular Dynamics (MD) analyses, with Fms-like tyrosine kinase (FLT3) and catalytic binding sites of Murine Leukemia Virus (MLV) as the target proteins in lukemia.

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Background: The process of stakeholder engagement in the implementation of a digital health platform is vital, especially in low-resourced countries like Cameroon, where the digital health ecosystem is still emerging. Stakeholder engagement can make meaningful contributions to a project allowing for increased project visibility and reach, uptake, acceptability, and sustainability. However, collaboration among stakeholders during stakeholder engagement cannot be implied.

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Background: One of the major causes of morbidity and death in children is malaria, and HIV infection and other factors may make the situation worse. This study aimed to assess the prevalence of malaria parasitemia among HIV-infected children under 15 years in the Bonassama Health District, Douala, Cameroon, and investigate its association with CD4 cell counts, viral load, and haematological parameters.

Methods: The study was a cross-sectional study involving 287 HIV-infected children <15 years and convenient sampling was used to enrol participants.

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Objectives: Infection prevention and control (IPC) contributes to the reduction of healthcare associated infections. Notwithstanding the global attention with available guidelines and tools, low- and middle-income countries (LMICs) still struggle to put into place effective IPC programmes. Here, we use a socioecological approach to summarize the findings of a recent workshop on the implementation of IPC activities in Cameroon.

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This study aims to explore the impact of Information and Communication Technologies (ICTs) on job acquisition for young people aged 15 to 35 in Cameroon. The research uses data from the fourth Cameroon Household Survey (CHS-4) conducted by the National Institute of Statistics (NIS) in 2014. The study compares the results with those of senior employees to highlight the digital divide.

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Article Synopsis
  • Tuberculosis (TB) is facing a significant challenge due to drug resistance, with Cameroon reporting a 1.4% prevalence of drug-resistant TB among new cases and 8.3% among those being retreated in 2022.
  • A study analyzed data from 2013 to 2022 in Cameroon, examining the trends, risk factors, and treatment outcomes related to drug-resistant TB, finding a total of 567 reported cases.
  • The study reported a high database quality (93.7%) and highlighted concerning treatment outcomes, including an 11.9% refusal rate and a 14.8% case fatality rate, with male gender and HIV-positive status identified as significant risk factors for poor treatment outcomes.
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This study applied social learning theory to understand how university students learned new health behaviors that impact their mental health through social media use. A cross-sectional research design was adopted with quantitative research methods to conduct the study. Data were collected using online questionnaires from a sample of 453 university students in Cameroon, Uganda and Nigeria.

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Introduction: Tonsillitis is a self-limiting inflammatory process of the tonsils. In high-income countries, guidelines have been developed to decide if a patient needs an antibiotic or not. These guidelines help to reduce unnecessary antibiotic prescriptions and prevent the development of antimicrobial resistance (AMR).

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  • HS-1793 is a new synthetic derivative of resveratrol, known for its health benefits like anticancer and anti-inflammatory effects, but has better bioavailability than resveratrol itself.
  • * It was discovered in 2007 and has shown promising results in metabolic processes, pharmacokinetics, and pharmacodynamics.
  • * The review discusses recent research on HS-1793, assessing its efficacy and setting the stage for future clinical trials in human diseases.*
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Background: Prognostic indices for patients with brain metastases (BM) are needed to individualize treatment and stratify clinical trials. Two frequently used tools to estimate survival in patients with BM are the recursive partitioning analysis (RPA) and the diagnosis-specific graded prognostic assessment (DS-GPA). Given recent advances in therapies and improved survival for patients with BM, this study aims to validate and analyze these 2 models in a modern cohort.

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The nutritional and functional properties of squashes are influenced by various factors, such as the stage of plant development, soil composition, and type of fertilizer. This study evaluates the impact of various organic fertilizers on D. properties.

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Comprehensive analysis of faults and diagnosis techniques in cascaded multi-level inverters.

Heliyon

November 2024

Laboratory of Technology and Applied Sciences, University Institute of Technology, University of Douala, PO Box: 8698, Douala, Cameroon.

Reliability is a crucial factor to consider for multi-level inverters (MLIs) used in industrial applications. With the increasing number of power semiconductor devices, the potential for defects to significantly degrade the overall system is heightened. A highly effective fault-detection technique is required to minimize the impact of faults.

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Context: Although AIDS-related deaths continue to decline, there are more people living with HIV than ever before. Sub-Saharan Africa remains disproportionately affected by the epidemic, with women aged 15-24 being over three times as likely to acquire HIV than their male counterparts. One reason for this disparity is that those engaging in 'transactional sex' do not benefit from governmental HIV prevention efforts.

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Introduction: COVID-19 is an infectious and contagious disease declared as public health emergency of international concern in 2020. Given its high morbidity and mortality, one of the responses to this pandemic is vaccination, which has posed a serious problem of acceptance among the population in sub-Saharan Africa (SSA) and Cameroon in particular. Thus, the purpose of this study was to contribute to a better response to the pandemic in Cameroon by measuring the effectiveness of the COVID-19 vaccine.

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Article Synopsis
  • * A cross-sectional survey conducted from August 2019 to April 2021 involved 1,477 adults over 18, with findings showing 37.1% experienced UI weekly, highlighting variations in UI types among countries—Cameron reported the highest at 40%, while Brazil had the lowest at 15%.
  • * Common symptoms identified included urinary urgency (59.9%) and nocturia (50.6%), with men reporting voiding issues more often, while women experienced
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This study aimed to analyze polymorphisms in Pfcrt, Pfmdr1, and Pfk13 genes' markers of resistance to Artemisinin-based combination therapy (ACT), in Plasmodium falciparum isolates from southern Brazzaville, 15 years after the adoption of ACT in the Republic of Congo. A total of 369 microscopy-confirmed malaria-infected individuals were enrolled from March to October 2021 in the community and in health facilities during a cross-sectional study. The K76T mutation in the Pfcrt gene, N86Y and Y184F mutations in the Pfmdr1 gene were investigated using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) while the codons region (1005-1300) of the Pfmdr1gene, and Pfk13 gene were sequenced.

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  • The paper explores hidden and coexisting self-excited multi-scroll attractors in semiconductor lasers using a modified rate equations model subjected to optical injection, highlighting the presence of multiple equilibria that attract trajectories from outside.
  • It analyzes the structural and dynamic properties of the new multi-scroll attractor, explaining how it emerges from the coupling of equilibria and provides 3D and contour plots through bifurcation analysis to depict its complex behaviors.
  • Lastly, an electronic circuit simulating REM-SCLs is developed in PSpice, confirming numerical results and achieving temporal control of optical wave management.
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Atmospheric concentrations of 7Be and 210Pb in weekly aerosols at Hirosaki, a heavy snowfall area in Japan.

Radiat Prot Dosimetry

November 2024

Institute of Radiation Emergency Medicine, Department of Radiochemistry and Radioecology, Hirosaki University, 66-1 Hon-cho, Hirosaki, Aomori 036-8564, Japan.

Article Synopsis
  • Aerosol samples were collected weekly in Hirosaki to study the concentrations of atmospheric 7Be and 210Pb, with total suspended particles ranging from 0.14 to 1.19 mg m-3 and an average of 0.29 mg m-3.
  • Both radionuclide activity concentrations showed similar trends and were measured to be between 0.46 to 4.94 mBq m-3 for 7Be and 0.26 to 1.29 mBq m-3 for 210Pb, suggesting they are influenced by the same environmental factors.
  • The study found that precipitation significantly affects radionuclide deposition, with factors like raindrop and snowflake characteristics playing a crucial role
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  • Trachoma is still a significant health issue in parts of Cameroon, particularly in the northern regions, where surveys from 2016-2022 revealed ongoing cases of active trachoma and trichiasis, despite previous interventions.
  • A total of 151,800 individuals were examined in these surveys, and findings indicated that two evaluation units exceeded the 5% threshold for active trachoma, while ten units exceeded the 0.2% threshold for trichiasis.
  • Continued intervention efforts, including mass antibiotic distribution and improved surgical access, are needed to address these health challenges, with future assessments required to gauge progress towards eliminating trachoma as a public health concern.
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  • H. pylori infection remains highly prevalent in Africa despite a decline, causing significant health issues in 10%-20% of those infected.
  • An online survey conducted across 21 African countries revealed that dyspepsia was the main reason for testing, with stool antigen tests and gastric biopsies being common diagnostic methods.
  • The study highlights the variability in healthcare practices and calls for the creation of localized, evidence-based management guidelines for H. pylori in Africa, facilitated by the African Helicobacter and Microbiota study group.
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  • Data on acute coronary syndrome (ACS) in Africa is insufficient, particularly regarding the increasing cases of premature ACS, highlighting the need for an epidemiological assessment to identify risk factors and improve management practices.
  • The European Atherosclerosis Society initiated the Lipid Registry of Africa (EAS-LIPRA) to create a standardized registry that collects and analyzes data on premature ACS across multiple African countries.
  • EAS-LIPRA aims to enhance understanding of ACS by stratifying data based on income levels and urban/rural residence, using valid statistical methods to compare demographics and management trends, potentially serving as a model for similar initiatives in other developing regions.
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Background: The genetic progression of the MDR1 gene in , a key factor in drug resistance, presents significant challenges for malaria control. This study aims to elucidate the genetic diversity and evolutionary dynamics of P. falciparum, particularly focusing on the MDR1 gene across multi-regional populations.

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Cervical Precancer Treatment Outcomes in Cameroon.

Int J MCH AIDS

September 2024

Department of Obstetrics and Gynecology, Faculty of Health Sciences, University of Buea, Cameroon.

Background And Objective: The ablative and excision treatment procedures are effective, accessible, and affordable in resource-constrained settings, but the rollout and posttreatment follow-up are not remarkable. The outcomes of treatment procedures among women treated for precancerous lesions of the cervix have not been adequately studied in Cameroon. This study assessed the outcome of ablative and excisional treatment procedures.

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