Sea level rise and coastal flooding risks in the Gulf of Guinea.

The Gulf of Guinea (GoG) is highly vulnerable to sea level rise, with projections indicating a significant increase in permanently inundated land by 2100, ranging from 1,458.1 to 4,331.7 km.

Organophosphate and carbamate susceptibility profiling of Anopheles gambiae sl. across different ecosystems in southern Benin.

Background: To overcome the spread of high pyrethroid resistance in the main malaria vectors and malaria disease persistence, it is crucial to look for effective and better resistance management strategies. Understanding the phenotypic profile of against alternatives insecticides like organophosphates and carbamates is crucial.

Methods: larvae and pupae were collected from the breeding sites in rice fields, pineapple crop areas, and peri-urban areas.

Examining the effectiveness of dissuasive taxes as a policy tool for reducing tobacco and alcohol consumption in Cameroon: A welfare and microsimulation analysis.

Deterrent taxes are a crucial policy tool for reducing the consumption of harmful products like tobacco and alcohol. However, assessing dissuasive taxes impact different income groups is important to ensure that their burden is not disproportionately borne by low-income households. This study examines the effectiveness of deterrent taxes as an economic policy tool for reducing tobacco and alcohol consumption in Cameroon.

An Alarming Eastward Front of Cassava Mosaic Disease in Development in West Africa.

Begomoviruses are a major threat to cassava production in Africa. Indeed, during the 1990s, the emergence of a recombinant begomovirus (East African cassava mosaic virus-Uganda, EACMV-Ug) resulted in crop devastation and severe famine in Uganda. In 2023, during a pre-survey of cassava farms at Forécariah, South-West Guinea, 22 samples showing peculiar cassava mosaic disease (CMD) symptoms were collected, and subsequent laboratory analysis confirmed the presence of EACMV-Ug in the samples.

RSM-CCD design of volcanic ash/ rice husk ash based phosphate geopolymer for crystal violet adsorption: kinetics and isotherms.

In this work, the application of central composite design (CCD) was used to optimise the synthesis of volcanic ash/ rice husk ash-based phosphate geopolymers. The effects of three factors namely, volcanic ash fraction, rice husk ash fraction and phosphoric acid concentration on porosity structure were investigated based on methylene blue index and iodine index as response variables. At optimized conditions of 3.

Implementing SARS-CoV-2 Testing during a Large-Scale Sporting Event in Africa: Lessons Learned from the Africa Football Cup of Nations Tournament in Cameroon.

During the 33rd Africa Cup of Nations (AFCON) football tournament in Cameroon, organizers and health authorities required a negative SARS-CoV-2 test result <48 hours before entry and provided free SARS-CoV-2 testing and vaccination at stadium and fan zone entrances. We describe the outcomes and implementation of mandatory SARS-CoV-2 testing at fan zones during AFCON. All consenting fan zones attendees were administered an electronic questionnaire capturing exposure factors, COVID-19-like symptoms, and COVID-19 vaccination status, before being tested for SARS-CoV-2 using an antigen rapid diagnostic test (Ag-RDT).

Decolonization in sexual and reproductive health research methods: a scoping review.

Background: As researchers and practitioners in the field of global health continue to acknowledge the ongoing impact of colonialism in their work, the call for decolonized research has increased. This has particular relevance in the field of sexual and reproductive health. Despite this recognized need, there is no singularly agreed upon definition of what it means to conduct decolonized research using decolonized methodologies.

Increasing Access to Palliative Care in Cameroon: Progress, Gaps, and Recommendations.

Background/objectives: Access to palliative care is an urgent global need. Countries with the greatest palliative care needs have limited access. In Cameroon, demand for palliative care is growing due to the rising incidence of life-limiting conditions.

[Factors Associated With Neonatal Mortality In Diamare, Cameroon].

Objective: To estimate the neonatal mortality rate, causes and factors associated to newborn deaths in Diamaré in Cameroon.

Patients And Methods: It was an analytical and retrospective cross-sectional study. The period of the study was from January 1 2018 to December 31 2019 in 11 health facilities in Diamaré.

Physicochemical properties and antioxidant potential of honey from Cameroon agroecological zones.

Cellular respiration produces reactive oxygen species (ROS), which can lead to oxidative stress and significant health issues, including chronic diseases and cancer. Antioxidants play a critical role in neutralizing ROS. This study investigates the physicochemical properties and antioxidant activities of honey sourced from five distinct agroecological zones in Cameroon.

An estimated photocurrent controlling the inductance current of DC-DC converter for rapid MPPT pursuit with less oscillations under sudden changes in the PV chain.

This paper focuses on simple technique from conventional techniques for the rapid maximum power point (MPP) pursuit with a less oscillations under sudden changes. In investigations, the controllability of the conventional boost converter model shows that the converter can be controlled from the current of its inductance (inductor). To get reference current, a conventional technique known as method of short-circuit current has been transformed to clearly establish with supporting evidence an estimated photocurrent.

Pierre & Hutch (Euphorbiaceae) Extracts and Isolated Compounds Reverse HIV-1 Latency.

Background: Pierre & Hutch is a tropical tree that grows in West and Central Africa, used in ethnomedicine to treat cancer, diabetes, headaches, convulsions, urinary diseases, and inflammatory diseases. As other species have been observed to possess chemical compounds that target HIV latency-reversal, we hypothesized that this species may have similar properties.

Aim Of The Study: The identification of extracts and compounds of this species, which have HIV-1 latency-reversing activity in J-Lat T cell lines.

Quinic acid enhances kanamycin efficacy against methicillin-resistant Staphylococcus aureus biofilms.

Background: Methicillin-resistant Staphylococcus aureus (MRSA) form biofilms that contribute to increased antimicrobial resistance, leading to treatment failure and/or relapse. It is, therefore, necessary to develop new antibiofilm strategies to eradicate MRSA biofilms related infections. This study was aimed to evaluate the effect of the combination of quinic acid and kanamycin against the preformed biofilms of methicillin-resistant Staphylococcus aureus.

The Chemical Space Spanned by Manually Curated Datasets of Natural and Synthetic Compounds with Activities against SARS-CoV-2.

Diseases caused by viruses are challenging to contain, as their outbreak and spread could be very sudden, compounded by rapid mutations, making the development of drugs and vaccines a continued endeavour that requires fast discovery and preparedness. Targeting viral infections with small molecules remains one of the treatment options to reduce transmission and the disease burden. A lesson learned from the recent coronavirus disease (COVID-19) is to collect ready-to-screen small molecule libraries in preparation for the next viral outbreak, and potentially find a clinical candidate before it becomes a pandemic.

SARS-CoV-2 cross-sectional serosurvey across three HIV-1 therapeutic clinical trials in Africa.

Objective: Data on the impact of COVID-19 in people living with HIV (PWH) are lacking in resource-constrained settings. We utilised existingrandomised clinical trials (RCTs) on antiretroviral therapies (ART) in HIV-1 infection to conduct a SARS-CoV-2 serosurvey, between January and March 2021, while characterising participants' features.

Design: Cross-sectional serosurvey.

Zoonotic and Food-Related Hazards Due to Hepatitis A and E in Africa: A Systematic Review and Meta-Analysis.

Introduction: Foodborne infections are caused by a wide spectrum of microbial pathogens, and they pose a significant global health threat, resulting in millions of cases and thousands of fatalities annually. Among these pathogens, human viruses, including Hepatitis A virus (HAV) and Hepatitis E virus (HEV), play a significant role in foodborne viral outbreaks, especially in Africa. This systematic review determined the prevalence of these viruses in livestock and produce in Africa.

Clustering of diet and physical activity behaviours in adolescents across home and school area-level deprivation in Cameroon, South Africa, and Jamaica.

Background: Adolescence is a crucial period for establishing healthy behaviours that can reduce the risk of noncommunicable diseases. However, limited data exist on the clustering of health-related behaviours, in adolescents from low- and middle-income countries (LMICs). This study examined how diet and physical activity behaviours cluster and how they are influenced by home and school area-level deprivation.

Early multi-cancer detection through deep learning: An anomaly detection approach using Variational Autoencoder.

Cancer is a disease that causes many deaths worldwide. The treatment of cancer is first and foremost a matter of detection, a treatment that is most effective when the disease is detected at an early stage. With the evolution of technology, several computer-aided diagnosis tools have been developed around cancer; several image-based cancer detection methods have been developed too.

Non-melanoma skin cancer in the context of albinism with an associated facial nerve palsy.

Introduction And Importance: Albinism, or the loss of pigment formation by otherwise healthy melanocytes, is quite common in Sub-Saharan Africa and is most likely caused by consanguinity. The sun's ultraviolet (UV) radiation and albinism have been both related to non-melanoma skin cancer (NMSC). Non-melanoma skin cancer (NMSC) and melanoma are the two main types of skin cancer.