Crimean Congo hemorrhagic fever virus exposure among febrile patients, cattle herders, and cattle herds in Cameroon.

Problem Addressed: Crimean Congo hemorrhagic fever (CCHF) is a tick-borne disease with high fatality rates and an expansive geographic distribution, yet disease prevalence data in Cameroon is lacking.

Objective: This study aimed to determine CCHF virus (CCHFV) seroprevalence and tick distribution among cattle herders and febrile patients in West and Centre Cameroon.

Methods And Approach: Two cross-sectional serological studies of human and cattle were conducted from October to December 2021 and from June to July 2022, which included the collection of ticks.

Piloting an Assessment Tool to Organize Surgical Care in Armed Conflicts: Findings From Cameroon.

Introduction: Armed conflict is increasing globally and is dramatically disrupting surgical care more than ever before. To address this, the PIPESS (Personnel, Infrastructure, Procedures, Equipment, Supplies, and Standard) tool was designed to facilitate assessment of hospital capacity. It assesses 6 key categories at 3 timepoints: preconflict, during conflict, and postconflict.

Maize plants can recover from fall armyworm damage under optimum crop production conditions in humid tropical agro-ecologies.

Farmers in Africa perceive the impact of fall armyworm (FAW) on maize to be significant, but field assessments have shown that yield losses are not significant enough to warrant pesticide interventions. This suggests that relationships between the crop stages, time, and duration of attack can affect the yield. Therefore, assessing the plant's recovery from damage using individual plants based on defoliation levels could guide whether and when pesticides should be applied.

The acceptance of COVID-19 vaccines in Rwanda: a cross-sectional study.

The first reported case of Coronavirus Disease 2019 (COVID-19) in Rwanda occurred on March 14 2020. By the end of July 2024, a total of 133,518 individuals had tested positive for the infection, resulting in 1,468 deaths and 132,039 had fully recovered. The success of COVID-19 elimination in Rwanda hinges on the public's level of acceptance of the COVID-19 vaccination.

Hybrid modeling approach for precise estimation of energy production and consumption based on temperature variations.

This study introduces an advanced mathematical methodology for predicting energy generation and consumption based on temperature variations in regions with diverse climatic conditions and increasing energy demands. Using a comprehensive dataset of monthly energy production, consumption, and temperature readings spanning ten years (2010-2020), we applied polynomial, sinusoidal, and hybrid modeling techniques to capture the non-linear and cyclical relationships between temperature and energy metrics. The hybrid model, which combines sinusoidal and polynomial functions, achieved an accuracy of 79.

A loop-mediated isothermal amplification test for yaws: a multi-country diagnostic accuracy evaluation.

Background: To meet the WHO target of eradicating yaws by 2030, highly sensitive and specific diagnostic tools are needed. A multiplex Treponema pallidum-Haemophilus ducreyi loop-mediated isothermal amplification (TPHD-LAMP) test holds promise as a near-patient diagnostic tool for yaws and H ducreyi. We conducted a prospective evaluation in Cameroon, Côte d'Ivoire, Ghana, and the Republic of the Congo to determine the diagnostic accuracy of the TPHD-LAMP test, as well as to assess its acceptability, feasibility, and cost.

Antimicrobial Resistance Profiles of Escherichia coli and Staphylococcus spp. Isolated from Locally Produced Fish and Imported Fish Sold in the Centre Region of Cameroon.

Antimicrobial resistance has emerged as a significant threat to global health, with the World Health Organization (WHO) classifying it among the top 10 public health threats. However, more epidemiological information is needed to support policy and stewardship programs. This study aimed to investigate the antimicrobial resistance profiles of Escherichia coli and Staphylococcus spp.

Unpredictable chronic mild stress induced anxio-depressive disorders and enterobacteria dysbiosis: Potential protective effects of Detariummicrocarpum.

Ethnopharmacological Relevance: Detarium microcarpum Guill. & Perr. is used traditionally in Far North Cameroun to treat stomach aches, anxiety, epilepsy, and other mental disorders.

Coronavirus disease 2019 outcomes in a population-based cohort of people with HIV and a matched cohort of people without HIV during Omicron variant waves.

We found that rates of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing and reverse transcriptase (RT)-PCR-confirmed infection were approximately 50% higher in a population-based cohort of people with HIV compared with a matched cohort of people without HIV during the Omicron era (2 January 2022 to 31 March 2023) in Ontario, Canada, after controlling for age, sex, residential census tract, and country of birth. Rates of coronavirus disease 2019 (COVID-19)-related hospitalization and/or death were more than double. Differences persisted independent of vaccination, healthcare access, and COVID-19 diagnosis.

Three-dimensional vegetation structure drives patterns of seed dispersal by African hornbills.

Three-dimensional (3D) vegetation structure influences animal movements and, consequently, ecosystem functions. Animals disperse the seeds of 60%-90% of trees in tropical rainforests, which are among the most structurally complex ecosystems on Earth. Here, we investigated how 3D rainforest structure influences the movements of large, frugivorous birds and resulting spatial patterns of seed dispersal.

Prevalence of Major Risk Factors and Assessment of 10-Year Risk for Cardiovascular Diseases Among Adults in Yaoundé, Cameroon: A Cross-Sectional Study.

Objective This study aimed to assess the prevalence of major risk factors for cardiovascular disease and the 10-year cardiovascular risk in an adult population residing in Yaoundé, Cameroon. Methodology We conducted a cross-sectional survey in 10 purposively selected neighbourhoods of Yaoundé, involving one adult per household who consented to participate. We collected data on personal and family history, lifestyle and nutritional habits, anthropometric parameters, and blood pressure, and calculated prevalence rates with 95% CI.

Prevalence and determinants of scabies among schoolchildren in Africa: A systematic review and meta-analysis.

Background: Scabies is one of the major neglected tropical diseases among children in deprived communities. Studies conducted among schoolchildren in Africa are limited and inconsistent. Thus, the aim of this study is to estimate the pooled magnitude and predictors of scabies in African schoolchildren.

Treatment switch from multiple daily insulin injections to sulphonylureas in an African young adult diagnosed with HNF1A MODY: a case report.

Background: Maturity onset diabetes of the young is one of the commonest causes of monogenic diabetes and can easily be mistaken for type 1 diabetes. A diagnosis of maturity onset diabetes of the young can have direct implications for genetic counseling, family screening, and precision diabetes treatment. However, the cost of genetic testing and identifying individuals to test are the main challenges for diagnosis and management in sub-Saharan Africa.

Advanced design and Engi-economical evaluation of an automatic sugarcane seed cutting machine based RGB color sensor.

There are many problems related to the use of machine learning and machine vision technology on a commercial scale for cutting sugarcane seeds. These obstacles are related to complex systems and the way the farmers operate them, the possibility of damage to the buds during the cleaning process, and the high cost of such technology. In order to address these issues, a set of RGB color sensors was used to develop an automated sugarcane seed cutting machine (ASSCM) capable of identifying the buds that had been manually marked with a unique color and then cutting them mechanically, and the sugarcane seed exit chute was provided with a sugarcane seed monitoring unit.

Application of a new highly multiplexed amplicon sequencing tool to evaluate antimalarial resistance and relatedness in individual and pooled samples from Dschang, Cameroon.

Background: Resistance to antimalarial drugs remains a major obstacle to malaria elimination. Multiplexed, targeted amplicon sequencing is being adopted for surveilling resistance and dissecting the genetics of complex malaria infections. Moreover, genotyping of parasites and detection of molecular markers drug resistance in resource-limited regions requires open-source protocols for processing samples, using accessible reagents, and rapid methods for processing numerous samples including pooled sequencing.

Exploring Medicinal Plants for Antimicrobial Activity and Synergistic Effects With Doxycycline Against Bacterial Species.

Medicinal plants are rich sources of bioactive compounds with diverse pharmacological properties, including antimicrobial activities. This study aimed to assess the antibiofilm potential of methanol and ethanol extracts from nine selected medicinal plants, as well as their synergistic effects with doxycycline against strains. Standard procedures were employed to determine the phytochemical composition, total phenolic, and flavonoid contents of the extracts.

Uncovering the drivers of food insecurity in Cameroon: insights from a nationwide cross-sectional analysis.

Background: Despite global efforts to achieve zero hunger, food insecurity remains a critical challenge in several African countries, including Cameroon. This study aims to identify sociodemographic predictors of food insecurity across Cameroon through a comprehensive, nationwide cross-sectional analysis.

Methods: Data for this study were drawn from the 2018 Cameroon Demographic and Health Survey (CDHS).

Prehospital factors associated with mortality among road traffic injury patients: analysis of Cameroon trauma registry data.

Background: Cameroon is amongst the worst affected countries by road traffic injuries with an estimated 1443 disability-adjusted life years per 100,000 population. There have been very limited reports on the crucial prehospital response to road traffic injuries in Cameroon. This study aimed to identify prehospital factors associated with RTI mortality in Cameroon.