4 results match your criteria: "Cambridge University Teaching Hospital NHS Trust[Affiliation]"

Systematic review and meta-analysis of the complications of salvage total laryngectomy.

Eur J Surg Oncol

January 2017

Department of Otolaryngology-Head & Neck Surgery, Westmead Hospital, Cnr Darcy & Hawkesbury Road, Westmead, NSW, 2145, Australia.

Background And Objectives: Management paradigms in laryngeal cancer have shifted to "organ preservation" chemoradiotherapy protocols. In the event of treatment failure, salvage total laryngectomy remains the only curative treatment option. However a comprehensive review of the complications of this procedure has not been reported.

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Introduction: We have previously reported the association of gastrointestinal and hypoglycemic symptoms, with idiopathic accelerated gastric emptying. We now report the first series of six similar cases.

Case Presentations: Patient 1: A 24-year-old Caucasian man presented to our facility with a six-month history of post-prandial nausea, flatulence, bloating, abdominal discomfort and associated diarrhea.

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Introduction: The majority of cases of post-prandial reactive hypoglycemia are considered idiopathic. Abnormalities of B-cell function and glucose regulation by insulin and glucagon have been postulated as causes but associated gastrointestinal dysfunction has not been reported. We report the first case of accelerated gastric emptying associated with post-prandial reactive hypoglycemia, abdominal bloating and diarrhea.

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Objectives/hypothesis: The objective was to analyze the clinical data and outcome of all the patients treated surgically for squamous carcinoma of the temporal bone in a tertiary referral department of skull base surgery over a 20-year period.

Study Design: Retrospective.

Methods: Thirty-nine patients with squamous carcinoma of the temporal bone were analyzed.

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