2 results match your criteria: "California. Electronic address: freeman@eyecenter.ucsd.edu.[Affiliation]"

Long-Term Results of Pro Re Nata Regimen of Aflibercept Treatment in Persistent Neovascular Age-Related Macular Degeneration.

Am J Ophthalmol

July 2016

Department of Ophthalmology, Jacobs Retina Center at the Shiley Eye Institute, University of California San Diego, La Jolla, California. Electronic address:

Purpose: To determine the 24-month results of patients who had pro re nata (PRN) aflibercept treatment owing to recurrent or resistant neovascular macular degeneration.

Design: Retrospective, interventional, consecutive case series.

Methods: Eighty-one eyes of 78 patients with resistant or multiple recurrences of intraretinal or subretinal fluid while receiving monthly bevacizumab or ranibizumab injections and were switched to strict, as-needed aflibercept treatment with every-8-weeks spectral-domain optical coherence tomography (SDOCT)-guided monitoring were included.

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Purpose: To evaluate temporal changes and predictors of accuracy in the alignment between simultaneous near-infrared image and optical coherence tomography (OCT) scan on the Heidelberg Spectralis using a model eye.

Design: Laboratory investigation.

Methods: After calibrating the device, 6 sites performed weekly testing of the alignment for 12 weeks using a model eye.

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