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Lymph Node Micrometastases in Early-Stage Cervical Cancer are Not Predictive of Survival.
Int J Gynecol Pathol
July 2015
Department of Obstetrics and Gynecology (M.P.S.), Division of Gynecologic Oncology Departments of Obstetrics and Gynecology (K.L.K.) Research Programs (R.S.H.), Walter Reed National Military Medical Center Uniformed Services University of the Health Sciences (C.M.Z.), Bethesda, Maryland SCL Physicians (P.J.B.S.), Denver, Colorado Department of Obstetrics and Gynecology (J.C.F., L.I.M.), Division of Gynecologic Oncology Departments of Pathology (J.C.F., C.A.A.) Preventive Medicine (S.G., W.Y.), University of Southern California Keck School of Medicine Kaiser Permanente Medical Center (S.E.L.), Los Angeles, California Sibley Memorial Hospital (M.R.C.), Washington, District of Columbia.
Although patients with early-stage cervical cancer have in general a favorable prognosis, 10% to 40% patients still recur depending on pathologic risk factors. The objective of this study was to evaluate if the presence of lymph node micrometastasis (LNmM) had an impact on patient's survival. We performed a multi-institutional retrospective review on patients with early-stage cervical cancer, with histologically negative lymph nodes, treated with radical hysterectomy and pelvic lymphadenectomy for the study period 1994 to 2004.
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