29,744 results match your criteria: "Calif; David Geffen School of Medicine at UCLA[Affiliation]"

Postmenopausal Endometriosis: Clinical Insights and Imaging Considerations.

Radiographics

December 2024

From the Department of Radiology and Diagnostic Imaging, Chamié Imagem da Mulher, Rua Casa do Ator 1117, CJ 72, São Paulo, SP 04546-004, Brazil (L.P.C.); Department of Radiology, Mayo Clinic, Rochester, Minn (W.M.V.B., L.X., P.C.A.); Department of Radiology, Clínica Izabela Pires Franco, Belém, Para, Brazil (I.V.P.F.); Imaging Institute, Cleveland Clinic Foundation, Cleveland, Ohio (M.K.F.); Department of Radiology, Massachusetts General Hospital, Boston, Mass (A.S.S.B.); Department of Radiology, Stanford University, Palo Alto, Calif (P.J.); and Department of Radiology, Mayo Clinic, Phoenix, Ariz (S.W.Y.).

Endometriosis is a chronic systemic condition characterized by the presence of ectopic endometrial-like tissue outside of the uterus. It occurs most often in reproductive-aged patients and less frequently in postmenopausal women. In postmenopausal patients, endometriosis is more common in those undergoing hormone replacement therapy or taking tamoxifen.

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Accelerated Cardiac MRI with Deep Learning-based Image Reconstruction for Cine Imaging.

Radiol Cardiothorac Imaging

December 2024

From the Institute of Diagnostic and Interventional Radiology, Pediatric Radiology and Neuroradiology (A.C.K., L.R., M.M., A.D., M.A.W., F.G.M.), and Department of Cardiology (C.I.L.), Rostock University Medical Center, Schillingallee 36, 18057 Rostock, Germany; GE HealthCare, Munich, Germany (M.G.); GE HealthCare, Menlo Park, Calif (X.Z.); and Department of Radiology, Ludwig-Maximilian University, Munich, Germany (R.L.).

Purpose To assess the influence of deep learning (DL)-based image reconstruction on acquisition time, volumetric results, and image quality of cine sequences in cardiac MRI. Materials and Methods This prospective study (performed from January 2023 to March 2023) included 55 healthy volunteers who underwent a noncontrast cardiac MRI examination at 1.5 T.

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Diagnostic Performance of AI-enabled Plaque Quantification from Coronary CT Angiography Compared with Intravascular Ultrasound.

Radiol Cardiothorac Imaging

December 2024

From the Department of Cardiology, Fiona Stanley Hospital, Perth, Australia (A.R.I.); Harry Perkins Institute of Medical Research, Curtin Medical School, Curtin University, 11 Robin Warren Dr, Murdoch, WA 6150, Australia (A.R.I.); Department of Radiology, St Paul's Hospital, University of British Columbia, Vancouver, Canada (G.T.); HeartFlow Inc, Mountain View, Calif (K.P., N.N., S.M.); Cardiovascular Research Foundation, Columbia University, New York, NY (A.M.); and Department of Cardiovascular Medicine, William Beaumont University Hospital-Corewell Health East, Royal Oak, Mich (R.D.S.).

Article Synopsis
  • The study evaluated the effectiveness of an AI tool (AI-QCPA) used in coronary CT angiography (CCTA) for measuring plaque volume compared to intravascular ultrasound (IVUS).
  • Analysis involved 33 patients who had serious heart attacks, with various imaging techniques performed on their coronary vessels shortly after treatment.
  • Results showed strong correlations between AI-QCPA and IVUS measurements, although the AI tool tended to slightly underestimate total and calcified plaque volumes while overestimating noncalcified plaque.
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Background: Patients with spastic equinus, equinovarus, and claw toe deformities can experience marked pain and functional limitations in the ability to weight-bear comfortably, ambulate efficiently, or mobilize independently. Seen in 80% of patients with cerebral palsy and 18% of patients with stroke (1, 2), the spastic foot and ankle deformities, and its secondary sequelae of static joint contractures, osseous changes, and chronic pain, are unfortunately common.

Methods: Adult and pediatric patients undergoing combined hyperselective and selective partial motor neurectomies for varus or claw toe deformities were reviewed.

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Objective: To determine factors significantly associated with alternative discharge destination (ADCD) following lobectomy, including the modified 5-item Frailty Index (mFI-5).

Methods: Patients in the 2017-2020 NSQIP who underwent elective lobectomy and were admitted from home were included, with ADCD defined as a patient who was discharged to any nonhome location. Four multivariable logistic regression models for ADCD were evaluated for predictive power.

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Article Synopsis
  • This study aimed to analyze the hemodynamics of a new animal model of Fontan physiology, which is important for understanding poor long-term outcomes in Fontan patients.
  • Researchers created a single-stage Fontan model in juvenile sheep and conducted detailed hemodynamic assessments.
  • Results showed that only a fraction of the sheep survived, with survival rates improving over time due to a learning curve; the study identified key hemodynamic characteristics but noted anatomical differences that affected the model's accuracy, suggesting surgical modifications could enhance future studies.
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The Impact of Complication Timing on the Outcomes of Implant-based Breast Reconstruction.

Plast Reconstr Surg Glob Open

November 2024

From the Division of Plastic and Reconstructive Surgery, Department of Surgery, University of California, Los Angeles, Calif.

Article Synopsis
  • The NSQIP database helps identify surgical complications but only tracks them for 30 days, raising concerns about its effectiveness for evaluating outcomes in breast reconstruction.
  • A study analyzed 301 patients who underwent mastectomy and immediate reconstruction, discovering that 58% had complications, with early complications occurring in 47% of cases and late complications in 12%.
  • Late complications significantly increased the likelihood of reconstructive failure and the need for flap procedures, suggesting that longer follow-up periods and detailed data are essential for improving national surgical databases like NSQIP.
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Article Synopsis
  • Aortic dissection, particularly Type B, is a common emergency in the U.S., and the study explored trends in treatment methods like thoracic endovascular repair (TEVAR) between 2010 and 2020.
  • Out of over 85,000 patients studied, fewer received TEVAR initially (decreasing from 11.3% to 9.6%), while more opted for it during later hospital visits (increasing from 13.0% to 21.6%).
  • The findings indicated that patients receiving early TEVAR had lower mortality rates but incurred higher hospital costs, while delayed TEVAR patients experienced fewer major complications without a significant increase in 90-day costs.
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Aquaporin-4 Immunoglobulin G-seropositive Neuromyelitis Optica Spectrum Disorder MRI Characteristics: Data Analysis from the International Real-World PAMRINO Study Cohort.

Radiology

November 2024

From the Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin & Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Lindenberger Weg 80, 13125 Berlin, Germany (C.C., H.Z., A.U.B., F.P.); NeuroCure Clinical Research Ctr (C.C., H.Z., A.U.B., J.W., F.P.), Dept of Psychiatry and Neurosciences, Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany (C.C.); Medical Image Analysis Center, Basel, Switzerland (V.C.e.S., E.G., D.M.); Paulista School of Medicine, Dept of Neurology and Neurosurgery (D.B.B.), Dept of Diagnostic Imaging, Universidade Federal de São Paulo, São Paulo, Brazil (M.I.I.); Koc Univ, School of Medicine Neurology Dept and Istanbul Univ, Cerrahpasa School of Medicine, Neurology Dept, Istanbul, Turkey (A.A.); Dept of Neurology, Istanbul Univ, Cerrahpasa Faculty of Medicine, Istanbul, Turkey (U.T.); Div of Neurology, Dept of Medicine, Siriraj Hosp, Mahidol Univ, Bangkok, Thailand (S.S.); Bumrungrad International Hosp, Bangkok, Thailand (S.S.); Center for Advanced Neurologic Research, KS Hegde Medical Academy, Nitte Univ, Mangalore, India (L.P., A.D.); Dept of Neurology, Hosp de S. João, Al. Hernâni Monteiro, Porto, Portugal (M.J.S., R.F.); MS Center at Swedish Neuroscience Inst, Seattle, Wash (P.Q., C.T.); Dept of Neurology and Neuroimmunology Clinic, Rabin Medical Center, Petach Tikva, Israel (I.L.); Sackler Faculty of Medicine & Felsenstein Medical Research Center, Tel Aviv Univ, Tel Aviv, Israel (I.L., H.S.K.); Dept of Radiology, Rabin Medical Center, Beilinson Hosp, Israel, and Sackler Faculty of Medicine, Tel-Aviv Univ, Tel Aviv, Israel (V.K.); Dept of Neurology and Neuroimmunology, Rabin Medical Center, Beilinson Hosp, Israel, and Sackler Faculty of Medicine, Tel-Aviv Univ, Tel Aviv, Israel (M.A.H.); Neuro-Ophthalmology Div, Dept of Ophthalmology, Rabin Medical Center, Petah Tikva, Israel (H.S.K.); Div of Neurology, Univ of Toronto, St Michael's Hosp, Toronto, Canada (D.L.R., L.W.); Mellen Center, Cleveland Clinic, Cleveland, Ohio (D.O.), Dept of Biomedical Engineering, Cleveland Clinic, Cleveland, Ohio (K.N.); Multiple Sclerosis and Neuroimmunology Program, Univ Hosps of Cleveland, Case Western Reserve Univ School of Medicine, Cleveland, Ohio (H.A., M.O.S.); Michigan Inst for Neurologic Disorders, Farmington Hills, Mich (Y.M.D.); Inst of Clinical Neuroimmunology, LMU Hosp, Ludwig-Maximillians Universität München, Munich, Germany (J.H.); Dept of Neurology, Slagelse Hosps, Odense, Denmark (N.A.); Insts of Regional Health Research & Molecular Medicine, Univ of Southern Denmark, Odense, Denmark (N.A.); Dept of Radiology, Aleris Hosp, Copenhagen, Denmark (P.B.S.); NYU Multiple Sclerosis Comprehensive Care Center, Dept of Neurology, NYU School of Medicine, New York, NY (I.K.); Dept of Neurology, Center for Neurology and Neuropsychiatry, LVR-Klinikum, Heinrich Heine Univ Düsseldorf, Düsseldorf, Germany (M.R.); School of Medicine and Dentistry, Gold Coast Campus, Griffith Univ, Queensland, Australia (S.B., S.A.); Dept of Neurology, Gold Coast Univ Hosp, Queensland, Australia (S.A.); Dept of Pediatrics, Univ of Utah, Salt Lake City, Utah (B.M., A.M.J., M.W., S.G., L.J.C.); Dept of Medicine, Divs of Molecular Medicine & Infectious Diseases, and Ludquist Inst for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, Calif (M.R.Y.); Dept of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, Calif (M.R.Y.); Depts of Ophthalmology and Visual Sciences, Kellogg Eye Center, Univ of Michigan, Ann Arbor, Mich (T.J.S.); Div of Metabolism, Endocrine and Diabetes, Dept of Internal Medicine, Univ of Michigan Medical School, Ann Arbor, Mich (T.J.S.); Hoffmann-LaRoche, Basel, Switzerland (J.W.); Dept of Neurology, Charité-Universitätsmedizin Berlin, Germany (F.P.); Affiliated author members of the Guthy-Jackson Charitable Foundation (GJCF) International Clinical Consortium (ICC) for NMOSD are listed in Appendix S1.

Article Synopsis
  • Patients with neuromyelitis optica spectrum disorder (NMOSD) often have antibodies against aquaporin-4 (AQP4), making MRI monitoring critical for understanding the disease's progression.
  • A retrospective study involved MRI data from 525 AQP4-IgG-seropositive NMOSD patients across 11 countries, focusing on the types and locations of lesions in the central nervous system.
  • Results showed a high prevalence of hyperintense lesions in the brain and significant patterns of myelitis in the spinal cord, emphasizing the importance of MRI in tracking this condition.
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CT/MRI LI-RADS 2024 Update: Treatment Response Assessment.

Radiology

November 2024

From the Department of Radiology, University of Michigan Health System, 1500 E Medical Center Dr, Ann Arbor, MI 48109-5030 (A.A., M.M.L.); Department of Radiology, Memorial Sloan Kettering Medical Center, New York, NY (V.C., R.D., H.Y.); Department of Radiology, Northwestern Medical Center, Chicago, Ill (F.H.M., R.J.L.); Department of Radiology, Duke University Medical Center, Durham, NC (M.B.); Department of Radiology, University of California San Diego, San Diego, Calif (C.S., C.Y.K.); Department of Radiology, University of Toronto, Toronto, Ontario, Canada (A.Z.K.); Department of Radiology, Massachusetts General Hospital, Boston, Mass (A.R.K., A.S.B.); Department of Radiology, Mount Sinai Medical Center, New York, NY (E.K.); Department of Radiology, Mayo Clinic Rochester, Rochester, Minn (D.O.); Department of Radiology, Weill Cornell Medical Center, New York, NY (R.A.C.); and Department of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC (L.M.B.).

With the rising incidence of hepatocellular carcinoma, there has been increasing use of local-regional therapy (LRT) to downstage or bridge to transplant, for definitive treatment, and for palliation. The CT/MRI Liver Imaging Reporting and Data System (LI-RADS) Treatment Response Assessment (TRA) algorithm provides guidance for step-by-step tumor assessment after LRT and standardized reporting. Current evidence suggests that the algorithm performs well in the assessment of tumor response to arterial embolic and loco-ablative therapies and fair when assessing response to radiation-based therapies, with limited data to validate the latter.

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Changes in Reader Performance During Sequential Reading of Breast Cancer Screening Digital Breast Tomosynthesis Examinations.

Radiology

November 2024

From the Department of Psychological and Brain Sciences, University of California-Santa Barbara, Santa Barbara, Calif (C.K.A.); Department of Biostatistics, University of Pittsburgh, Pittsburgh, Pa (A.I.B.); Department of Radiology, University of Pittsburgh Medical Center, Magee-Womens Hospital, 300 Halket St, Pittsburgh, PA 15213 (A.I.B., M.L.Z.); and Department of Psychology, University of Nevada-Reno, Reno, Nev (M.K.P., M.A.W.).

Background Studies suggest that readers experience perceptual adaptation when interpreting batched screening mammograms, which may serve as a mechanism for improved performance. Purpose To analyze clinical digital breast tomosynthesis (DBT) screening data to evaluate changes in reader performance during sequential batch reading. Materials and Methods This observational retrospective study used data from the radiology information system collected for screening DBT examinations performed from January 2018 to December 2019.

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Objectives: To evaluate the use of systemic therapy and overall survival in patients with resected non-small cell lung cancer whose pathologic tumor size was within 2 mm of a T-stage cutoff.

Methods: This was retrospective cohort study using the National Cancer Database of patients who underwent resection of tumors within 2 mm of the T1c/T2a, T2a/T2b, and T2b/T3 T-stage cutoffs. Patients with nodal involvement or whose T stage was determined on the basis of pathologic features other than tumor size were excluded.

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Article Synopsis
  • - Food Protein-Induced Enterocolitis (FPIES) is a type of food allergy that occurs primarily in children and is characterized by symptoms such as delayed vomiting, lethargy, and pale skin, typically emerging 1-4 hours after consuming the allergen.
  • - Despite increasing recognition of FPIES, its exact causes remain unknown, and there are no specific tests to diagnose or track the condition's progress.
  • - A recent workshop by the National Institute of Allergy and Infectious Diseases (NIAID) focused on FPIES, discussing current understanding, research gaps, and future priorities for improving diagnosis and management.
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Prevalence and outcomes of cancer and treatment-associated toxicities for patients with ataxia telangiectasia.

J Allergy Clin Immunol

November 2024

A-T Clinical Center, Johns Hopkins Hospital, Baltimore, Md; Department of Hematology, St Jude Children's Research Hospital, Memphis, Tenn. Electronic address:

Article Synopsis
  • Ataxia telangiectasia (A-T) is a genetic disorder that affects DNA repair and increases the risk of developing cancers, with 16.5% of affected individuals diagnosed with primary cancers in a study.
  • The analysis revealed that the cumulative incidence of cancer reached 29% by age 35, with non-Hodgkin lymphoma being the most common hematologic cancer, while solid tumors were more prevalent in individuals aged 18 and over.
  • The study found that standard chemotherapy led to a higher risk of death and significant treatment-related toxicities, emphasizing the necessity for more effective and safer treatment options for individuals with A-T.
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Assembling the Pediatric Emergency Medicine Social Care Toolkit: A Modified Delphi Study.

Acad Pediatr

November 2024

Department of Emergency Medicine (EW Fleegler), Massachusetts General Hospital, Harvard Medical School, Boston, Mass.

Background: The pediatric emergency department is a high-value site for screening and resource referral for health-related social needs. However, best practices for this unique environment remain unclear. This study's objective was to introduce a consensus-based social care training toolkit for the pediatric emergency medicine (PEM) setting.

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An Untold Story: The Feelings of Pediatric Residents Early in the COVID-19 Pandemic and What They Can Teach Us Today.

Acad Pediatr

November 2024

Division of Emergency Medicine (DJ Schumacher), Cincinnati Children's Hospital Medical Center, Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, Ohio.

Objective: To understand the feelings of pediatrics residents early in the COVID-19 pandemic and to offer insights still relevant today.

Methods: We performed a thematic analysis exploring resident feelings early in the pandemic using free-text responses on a national survey distributed between May and June 2020. We analyzed responses from the following multi-part free text question embedded in the larger survey, "Which of the following feelings have you experienced in your role as a pediatric resident during the COVID-19 pandemic" with response prompts including relief, guilt, pride, sadness, worry, fear, and other.

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The Multiple Facets of Cow's Milk Allergy.

J Allergy Clin Immunol Pract

November 2024

Division of Allergy, Immunology & Retrovirology, Baylor College of Medicine, Houston, Texas. Electronic address:

Cow's milk allergy (CMA) is one of the most common food allergies in early childhood. CMA has varied presentations and multiple facets. A detailed clinical history is key for classification.

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Minimally invasive treatments for chronic low back pain.

JAAPA

December 2024

At the time this article was written, Chelsey M. Hoffmann was academic co-director of the PA program at the Mayo Clinic School of Health Science in Rochester, Minn. She now practices in the Department of Pain Medicine, Division of Anesthesiology, at the Mayo Clinic in Rochester, Minn. Ryan Mattie practices at Total Spine Institute in Los Angeles, Calif. Samir J. Sheth practices at Sutter Health in Roseville, Calif. Ryan S. D'Souza is director of neuromodulation and a consultant in the Department of Pain Medicine, Division of Anesthesiology, at the Mayo Clinic. Ms. Hoffmann discloses that she provides general consulting for SPR Therapeutics and Nalu Medical. Dr. Sheth is a consultant for SPR, Medtronic, Boston Scientific, and Vertos. Dr. D'Souza has an investigator-initiated grant with Nevro Corp. The authors have disclosed no other potential conflicts of interest, financial or otherwise.

This article describes minimally invasive treatments for managing chronic low back pain (LBP) related to lumbar spinal stenosis, facetogenic LBP, vertebrogenic LBP, or discogenic LBP. We also propose a clinical decision-making tool to guide clinicians in appropriate patient selection for various treatments.

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Background: Tobacco smoke may affect atopic dermatitis (AD) because of its known effects on humoral and cellular immunity, but prior studies lack data on disease severity and biomarkers over time.

Objective: We investigated the association between passive and active tobacco smoke exposure (TSE) during childhood and adolescence and the activity and severity of AD.

Methods: A birth cohort of 10,521 individuals was followed through adolescence as part of the Avon Longitudinal Study of Parents and Children.

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Background: Results from the POISED trial suggest that discontinuation of peanut oral immunotherapy can increase the risk of regaining clinical reactivity to peanut.

Objective: We sought to determine whether patients who achieved sustained unresponsiveness (SU) or sustained high threshold (SHT) have different baseline sequential epitope-specific IgE profiles than patients who achieved transient desensitization.

Methods: Subjects in the POISED trial (NCT02103270) were randomized to peanut (n = 95) or placebo (n = 25) for 24 months.

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Diabetes has classically been associated with atherosclerotic cardiovascular disease. However, heart failure is now increasingly recognized as a prevalent and often first cardiovascular complication among patients with diabetes. Investigation of this epidemiological relationship has led to recognition of diabetic cardiomyopathy, or structural heart disease that develops in patients with diabetes and may lead to progressive heart failure independently of coronary artery disease or conventional cardiovascular risk factors such as hypertension.

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RSNA 2023 Abdominal Trauma AI Challenge: Review and Outcomes.

Radiol Artif Intell

January 2025

From the Department of Medical Imaging, St Michael's Hospital, Unity Health Toronto, 30 Bond St, Toronto, ON, Canada M5B 1W8 (S.H., Z.H., H.M.L., I.Y., E.C.); Edward S. Rogers Department of Electrical and Computer Engineering, University of Toronto, Toronto, Ontario, Canada (Z.H., E.S.); The Jackson Laboratory, Bar Harbor, Me (R.L.B.); Department of Radiology, The Ohio State University, Columbus, Ohio (L.M.P.); Department of Medical Imaging, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada (F.H.B.); Department of Radiology, Scripps Clinic Medical Group and University of California San Diego, San Diego, Calif (J.D.R.); Radiological Society of North America, Oak Brook, Ill (M.V.); Department of Radiology, Thomas Jefferson University, Philadelphia, Pa (A.E.F.); Department of Radiology, Weill Cornell Medicine, New York, NY (G.S.); Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, Calif (J.M.), Department of Radiology, Vancouver General Hospital, Vancouver, Canada (S.N.); Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY (B.S.M.); Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Conn (M.A.D.); Duke University School of Medicine, Durham, NC (K.M.); North York General Hospital, Toronto, Ontario, Canada (E.S.); and Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada (E.C.).

Purpose To evaluate the performance of the winning machine learning models from the 2023 RSNA Abdominal Trauma Detection AI Challenge. Materials and Methods The competition was hosted on Kaggle and took place between July 26 and October 15, 2023. The multicenter competition dataset consisted of 4274 abdominal trauma CT scans, in which solid organs (liver, spleen, and kidneys) were annotated as healthy, low-grade, or high-grade injury.

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SCIseg: Automatic Segmentation of Intramedullary Lesions in Spinal Cord Injury on T2-weighted MRI Scans.

Radiol Artif Intell

January 2025

From the NeuroPoly Laboratory, Institute of Biomedical Engineering, Polytechnique Montréal, 2500 Chemin de Polytechnique, Montréal, Québec, Canada H3T 1J4 (E.N.K., J.V., J.C.A.); Mila-Quebec AI Institute, Montréal, Québec, Canada (E.N.K., J.V., J.C.A.); Department of Neurosurgery and Department of Neurology, Faculty of Medicine and Dentistry, Palacký University Olomouc, Olomouc, Czechia (J.V.); Department of Physical Medicine and Rehabilitation Physical Therapy Program, University of Colorado School of Medicine, Aurora, Colo (A.C.S.); Spinal Cord Injury Center, Balgrist University Hospital, University of Zürich, Zürich, Switzerland (D.P., S.S.S., L.F., P.F.); Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, Calif (D.P., K.A.W.); Department of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (P.F.); and Functional Neuroimaging Unit, CRIUGM and Centre de Recherche du CHU Sainte-Justine, Université de Montréal, Montréal, Québec, Canada (J.C.A.).

Article Synopsis
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Achieving More with Less: Combining Strong and Weak Labels for Intracranial Hemorrhage Detection.

Radiol Artif Intell

November 2024

From the Institute of Radiology and Nuclear Medicine, Cantonal Hospital Baselland, Rheinstrasse 26, 4410 Liestal, Switzerland (T.A.D.); and Department of Radiology, University of California San Diego, San Diego, Calif (J.D.R.).

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