Advancements and progress in juvenile idiopathic arthritis: A Review of pathophysiology and treatment.

Juvenile idiopathic arthritis (JIA) is a chronic clinical condition characterized by arthritic features in children under the age of 16, with at least 6 weeks of active symptoms. The etiology of JIA remains unknown, and it is associated with prolonged synovial inflammation and structural joint damage influenced by environmental and genetic factors. This review aims to enhance the understanding of JIA by comprehensively analyzing relevant literature.

Barriers and shortcomings in access to cardiovascular management and prevention for familial hypercholesterolemia during the COVID-19 pandemic.

Familial hypercholesterolemia (FH) is a hereditary condition caused by mutations in the lipid pathway. The goal in managing FH is to reduce circulating low-density lipoprotein cholesterol and, therefore, reduce the risk of developing atherosclerotic cardiovascular disease (ASCVD). Because FH patients were considered high risk groups due to an increased susceptible for contracting COVID-19 infection, we hypothesized whether the effects of the pandemic hindered access to cardiovascular care.

A review of current trends in HIV epidemiology, surveillance, and control in Nigeria.

The HIV epidemic remains a public health challenge in Nigeria, with about 1.9 million people living with the virus in 2020. Despite progress in controlling the epidemic, challenges remain, including inadequate funding and limited access to prevention and treatment services for key populations.

Sequence analysis reveals asymptomatic infection with and possibly leads to infertility in females: A cross-sectional study.

Background: Genetic evidence of asymptomatic () and () infection associated with infertility among females is lacking because suitable high throughput molecular methods have not been applied.

Objective: This study aimed to explore the occurrence of and in the genital tract of females with asymptomatic infection and infertility as well as determine their genetic relatedness.

Materials And Methods: The study group included 100 asymptomatic females and 31 females diagnosed with infertility.

Metabolic dysfunctions in Nigerian pre-eclamptics.

Aim: The patho-physiology of pre-eclampsia is not fully understood. This study determined the plasma levels of markers of oxidative stress, thyroid hormones, nitric oxide, C-reactive protein, and nutritional profiles in pre-eclamptic patients.

Methods: Thirty-two pregnant women with pre-eclampsia and 40 women with normal pregnancy (controls) participated in this study.