Assessing the Link between Maternal Transport Modes and Childhood Mortality in Nigeria.

Objectives: The study explored the association between maternal transport modes and childhood mortalities in Nigeria.

Method: Utilizing data and definitions from the 2018 Nigeria Demographic and Health Survey report, the ten-year early mortality rates of the five childhood mortalities and the percentage of live births in the 5 years before the survey, transported by eight identified means of transportation, were statistically correlated for each of Nigeria's 36 states and the federal capital territory (FCT) in the R environment at a significance level of α < 0.05.

A comprehensive review of iPS cell line-based disease modelling of the polyglutamine spinocerebellar ataxias 2 and 3: a focus on the research outcomes.

Spinocerebellar ataxias (SCAs) are a rare autosomal dominant neurodegenerative disorder. To date, approximately 50 different subtypes of SCAs have been characterized. The prevalent types of SCAs are usually of PolyQ origin, wherein the disease pathology is a consequence of multiple glutamine residues being encoded onto the disease proteins, causing expansions.

Spilanthes filicaulis (Schumach. &Thonn.) C. D. Adams: An insights into ethnopharmacologically important but scientifically understudied species.

Spilanthes filicaulis (Schumach. & Thonn.) C.

Advancements and progress in juvenile idiopathic arthritis: A Review of pathophysiology and treatment.

Juvenile idiopathic arthritis (JIA) is a chronic clinical condition characterized by arthritic features in children under the age of 16, with at least 6 weeks of active symptoms. The etiology of JIA remains unknown, and it is associated with prolonged synovial inflammation and structural joint damage influenced by environmental and genetic factors. This review aims to enhance the understanding of JIA by comprehensively analyzing relevant literature.

A Comparative Study of Genetic Diversity and Multiplicity of Infection in Uncomplicated Infections in Selected Regions of Pre-Elimination and High Transmission Settings Using and Genes.

Background: Understanding the genetic structure of . population in different regions is pivotal to malaria elimination. Genetic diversity and the multiplicity of infection are indicators used for measuring malaria endemicity across different transmission settings.

Bioactivity properties of hydroxyapatite/clay nanocomposites.

The need for bioactive and non-toxic biomaterials is on a high demand in tissue engineering applications nowadays. Hydroxyapatite (HAp) is the chief constituent of teeth and bones in mammas. One of the major challenges with the use of HAp in engineering application is its brittleness and to overcome this, it's important to react it with a material that can enhanced it's fragility.

A STUDY OF SKIN SEPSIS AMONGST ABATTOIR WORKERS IN MONIYA, IBADAN, OYO STATE, NIGERIA.

Background: Skin sepsis is a pyodermal infection caused by Lancefield's group streptococci and . It is characterized by discolored and mottled skin, cellulitis, impetigo and multi-systemic collagen muscularitis and can be transmitted from person to person.

Objective: This study sampled the skin of consented abattoir workers in Moniya Ibadan, for clinical sepsis, with a view to establishing a causal relationship between the infection obtained and the abattoir workers examined.

Closing potential drivers of antimicrobial resistance: last-resort antimicrobials with the potential of being misused, the way forward - a short communication.

Antimicrobial resistance (AMR) is still a formidable global public health challenge, as microorganisms, including bacteria, viruses, fungi, and parasites, evolve resistance to commonly used drugs, particularly antibiotics. The preservation of last-resort antimicrobials is critical for treating multi-drug-resistant infections; however, their indiscriminate use can exacerbate AMR crisis. This short communication delves into the multifaceted challenges, innovative strategies, and promising future directions to combat AMR effectively.

Barriers and shortcomings in access to cardiovascular management and prevention for familial hypercholesterolemia during the COVID-19 pandemic.

Familial hypercholesterolemia (FH) is a hereditary condition caused by mutations in the lipid pathway. The goal in managing FH is to reduce circulating low-density lipoprotein cholesterol and, therefore, reduce the risk of developing atherosclerotic cardiovascular disease (ASCVD). Because FH patients were considered high risk groups due to an increased susceptible for contracting COVID-19 infection, we hypothesized whether the effects of the pandemic hindered access to cardiovascular care.

A review of current trends in HIV epidemiology, surveillance, and control in Nigeria.

The HIV epidemic remains a public health challenge in Nigeria, with about 1.9 million people living with the virus in 2020. Despite progress in controlling the epidemic, challenges remain, including inadequate funding and limited access to prevention and treatment services for key populations.

Bacteriological Quality and Biotoxin Profile of Ready-to-Eat Foods Vended in Lagos, Nigeria.

A comprehensive study of bacterial and biotoxin contaminants of ready-to-eat (RTE) foods in Nigeria is yet to be reported. Hence, this study applied 16S rRNA gene sequencing and a dilute-and-shoot LC-MS/MS method to profile bacteria and biotoxins, respectively, in 199 RTE food samples comprising (n = 30) bread (n = 30), shawarma (n = 35), (n = 35), biscuits (n = 34), and (n = 35). A total of 631 bacterial isolates, clustered into seven operational taxonomic units, namely , , , and , , and , that are reported for the first time were recovered from the foods.

Comparing the effect of social media-based drama, music and art therapies on reduction in post-traumatic symptoms among Nigerian refugees of Russia's invasion of Ukraine.

Purpose: The objective of this study was to ascertain the effectiveness of social media-based music, art and drama therapies in treating PTSD symptoms among Nigerian evacuees from the Russia-Ukraine war.

Design And Methods: This study was a quasi-experiment involving a sample of 330 participants that were randomly assigned to control and treatment groups. The treatment group was further classified into three groups according to the different contents of the therapies they received.

Prevalence and Risk Factors of Genital Human Papillomavirus Infections among Women in Lagos, Nigeria.

Regional variations exist in HPV prevalence worldwide despite reports of high prevalence rates among African women. Limited data on genital HPV prevalence necessitated this study with the aim of determining the prevalence of genital HPV and associated risk factors among women in Lagos, Nigeria. Exfoliated cervical cells were collected with consent from 165 women using a cervical brush.

Phylogeny-based identification of in a Nigerian population of apparently healthy sexually active female students.

Introduction: Mycoplasma genitalium is an emerging sexually transmitted pathogen. Sexually transmitted infection (STI) is still a burden for Nigerian women because it is asymptomatic. The lack of detection of M.

Systematic mapping of DNAzymes research from 1995 to 2019.

DNAzymes (catalytic DNA) have gained significant diagnostic and therapeutic applications with increasing research output over the years. Functional oligonucleotides are used as molecular recognition elements within biosensors for detection of analytes and viral infections such as SARS-CoV-2. DNAzymes are also applied for silencing and regulating cancer specific genes.

Synergistic enhancement of rat intestinal alkaline phosphatase activity by taurine and sodium butyrate protects against endotoxin-induced bowel inflammation.

The effect of sodium butyrate (SB) and taurine on rat intestinal alkaline phosphatase (RIA) and the effect of the interaction of taurine and/or SB with bacterial lipopolysaccharides on ALP activity were investigated. In vitro analysis of the activity of RIA was carried out using various concentrations of SB and/or taurine. Substrate concentration-dependent kinetic study was performed at 1-10 mM of taurine and SB at 5.

Sequence analysis reveals asymptomatic infection with and possibly leads to infertility in females: A cross-sectional study.

Background: Genetic evidence of asymptomatic () and () infection associated with infertility among females is lacking because suitable high throughput molecular methods have not been applied.

Objective: This study aimed to explore the occurrence of and in the genital tract of females with asymptomatic infection and infertility as well as determine their genetic relatedness.

Materials And Methods: The study group included 100 asymptomatic females and 31 females diagnosed with infertility.

A review of some common African spices with antihypertensive potential.

Hypertension is the most common non-communicable disease, with about 1.28 billion hypertensive people worldwide. It is more prevalent in men than women and more common in the elderly.

The epidemiology and chemotherapeutic approaches to the control of urinary schistosomiasis in school-age children (SAC): a systematic review.

Background: Human schistosomiases are acute and chronic infectious diseases of poverty. Currently, epidemiological data of urinary schistosomiasis (US) in school-age children (SAC) and adults are often reported together making it difficult to ascertain the true status of the disease. Based on this premise, we set out to carry out this review.

Statistical analysis of bank deposits dataset.

This article presents the statistical analysis of the deposit activities in each of the account types of a leading bank in Nigeria. The mean effect of these account types on the bank was determined using analysis of variance (ANOVA). Further test which include the Tukey's simultaneous test for differences of means was also conducted.

Rapid mapping of urinary schistosomiasis: An appraisal of the diagnostic efficacy of some questionnaire-based indices among high school students in Katsina State, northwestern Nigeria.

Background: In sub-Saharan Africa, over 200 million individuals are estimated to be infected with urinary and intestinal schistosomiasis. In a bid to lay a foundation for effective future control programme, this study was carried out with the aim of assessing the diagnostic efficacy of some questionnaire-based rapid assessment indices of urinary schistosomiasis.

Methodology: A total number of 1,363 subjects were enrolled for the study.

Effect of 2 Models of Care and Factors Predicting Patients' Adherence to Doctor's Appointment Attendance in Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria.

Background: Provision of antiretroviral therapy in resource limited settings has put pressure on the available infrastructure.

Objectives: The study examined patients' adherence to Doctor's appointment attendance after an intervention changing the model of care and factors that predicted adherence.

Methods: Observational study was carried out over four years.

HIV/AIDS communication in four Nigerian mainstream newspapers.

Introduction: One consensus in discussions on HIV/AIDS communication in low and middle income countries (LMICs) is the need for communication models to focus on activity rather than cognitive indicators in order to achieve desired improvements in health behaviors and outcomes. Past failures of HIV/AIDS communication efforts in LMICs have been attributed to emphasis on cognitive indicators. This study analyses HIV/AIDS communication models in Nigerian newspapers.