Non-adenomatous non-epithelial carcinoma (hemangiopericytoma) of prostate treated with conservative surgery followed by adjuvant chemoradiation.

Hemangiopericytoma is a malignant vascular tumour of soft tissue. Microscopically, the tumour shows tightly packed cellular areas surrounding thin-walled branching blood vessels. Traditionally these tumours are treated using wide surgical excision.

Hepatitis B Prevalence during pregnancy.

In order to determine the efficacy of a new hepatitis B immune globulin (HBIG), a phase 3, vertical transmission (mother to child) clinical interventional trial of hepatitis B virus (HBV) post exposure prophylaxis (PEP) was conducted at selected sites (n=15) throughout India. This required a large screening program for HBsAg positivity at prenatal clinics located in tertiary care hospitals. 36,379 pregnant women consented to be tested for Hepatitis B surface antigen (HBsAg) by Rapid Test and if positive-confirmed by ELISA.

Clinicoepidemiological scoring system for early diagnosis of pediatric HIV.

This pilot study was aimed at testing the feasibility of using a standardized questionnaire as a screening tool for detection of pediatric HIV at first contact. A prospective study was carried out on a cohort of 400 new patients attending the pediatric outdoor patient department in Medical College, Kolkata. After examining, the attending physician noted his clinical impression, filled the standardized questionnaire and scored each patient.

Improvised laparoscopic stone picker.

Laparoscopic cholecystectomy is the treatment of choice for calculus cholecystitis. It is frequently complicated by stone spillage and retrieval of these stones is a cumbersome process which is frequently complicated by injuries. Moreover left over stones frequently leads to complication.

Effect of pre-existing malnutrition on growth parameters in HIV-infected children commencing antiretroviral therapy.

Background: Growth in HIV-infected children generally improves with antiretroviral therapy (ART). Little is known about the effect of pre-existing malnutrition on response to treatment.

Aim: To evaluate prospectively the effect of pre-existing malnutrition on growth of HIV-infected children commenced on ART compared with those without pre-existing malnutrition.

Evidence for tyrosinase as a beta1,6 branch containing glycoprotein: substrate of GnT-V.

Tyrosinase is a rate-limiting enzyme in mammalian melanogenesis, and is known as a glycoprotein. Post-translational processing of mammalian tyrosinase is required for its folding, sorting, and for enzymatic activity. Here we show for the first time that the mammalian tyrosinase has beta1,6-branched N-glycan structure that can be recognized by binding with specific lectin Leukoagglutinating phytohematoagglutinin (L-PHA).

Holoprosencephaly--a case report.

A newborn female with delayed initiation of respiration was presented. She was born at term, normally of an uncomplicated pregnancy. Her head circumference was 40.

A case report of unifocal Langerhans' cell histiocytosis or eosinophilic granuloma.

A case of unifocal Langerhans' cell histiocytosis or eosinophilic granuloma in a child is reported where the frontal, zygomatic and maxillary bones of the left orbital wall are affected. As eosinophilic granuloma is a rare disease and the involvement of maxillary bone in orbital eosinophilic granuloma is not well documented in the literature, this case is reported for its unusual involvement of 3 bones at a single site. The diagnosis was established by clinical, radiological and histological findings.

Action for tackling malnutrition: growth monitoring or surveillance?

Malnutrition is an important Public Health problem globally as well as in India. Mortality is a multi-causal phenomenon in which malnutrition is but one factor directly or indirectly contributing 55% mortality of children under-five years of age. Authors observed higher prevalence of severe degree of Malnutrition in the underserved section of population with specific reference to girl child, under 3 years of age, where there were large number of children in the family, repeated infections and Measles.

National rural health mission--opportunity for Indian Public Health Association.

Indian Public Health Association (IPHA) welcomes the release of National Rural Health Mission (NRHM) documents. It suggests that manpower requirements of the Community Health Centre (CHC) should be rationally determined on the basis of work and patient load of the CHC. Importance should be given on availability of simple & life saving equipment, female staff when male staff is not available.

Separation of thoraco-omphalopagus Siamese twin.

A pair of female thoraco-omphalopagus twins, with two pairs of lungs, common diaphragm and separate pleural cavities was separated at the age of 5(1/2) months after a parasitic relationship had developed between them. Before separation both the babies developed recurrent respiratory tract infection and frequent diarrhea. They were treated with medical therapy and made fit for anesthesia.

Diagnosis of symptomatic kala-azar by polymerase chain reaction using patient's blood.

Background: Detection of Leishmania parasite in patients by classical methods at the early stage of infection is limited. Several studies have shown that polymerase chain reaction (PCR) is more effective for the diagnosis of visceral Leishmaniasis (VL) in clinical samples. The purpose of this study was to develop a simple, specific and sensitive PCR-based assay for detecting VL caused by any species of the genus Leishmania.

Role of mycobacterium w as adjuvant treatment of lung cancer (non-small cell lung cancer).

Mycobacterium w (immuvac), a new potent immunomodulator was evaluated as an adjuvant therapy in the management of non-small cell lung cancer in a controlled clinical trial. The standard therapy employed was combination chemotherapy in the form of cisplatin and etoposide along with radiotherapy. The group receiving mycobacterium w tolerated the chemotherapy and radiotherapy well and completed it as planned, in contrast to premature stoppage of radiotherapy in 50% of patients in the control group.

Impact of modified leprosy elimination campaign in a MDT pilot project district of India.

A study was carried out based upon the data available from National Leprosy Eradication Program of Purulia district in West Bengal. The result showed that the disease was in a declining trend up to the year 1998 and was inclining during the year 1998-1999 due to more case detection through MLEC-I, then followed by declining trend during the year 2000 as it was observed by MLEC-II. Single skin lesion rate was higher, MB rate was same and reduced deformity rate indicates early detection of cases due to better awareness of the community about the disease.

Splenectomy and splenic slice grafting in the management of thalassemia.

Over the last decade and a half, we performed a splenectomy along with slice grafting of the spleen in 170 (beta28 and Ebeta 142) transfusion-dependent, high-risk thalassemic patients. Of these, 17 were selected for study of the fate of the grafts and their immune status before and after operation. The procedure had equally good advantages of splenectomy and immunoconservation as partial splenectomy, partial splenic embolization, or partial splenic dearterialization, if not better, but none of the disadvantages of the other procedures.

Juvenile nasopharyngeal angiofibromas with unique extrapharyngeal extensions.

From June 1999 to May 2000, 13 canes of Juvenile nasopharyngeal angiofibroma were diagnosed and treated in our department. From this series, 3 cases are highlighted here for their unusual extrapharyngeal presentation. Bio-mechanisms of these spreads are described.

Bradycardia, reversible panconduction defect and syncope following self-medication with a homeopathic medicine.

Alkaloid extracts from the plant Aconitum species have been used in various forms of herbal remedies predominantly as anti-inflammatory and analgesic agents. Many of these alkaloids are extremely potent cardiotoxins and documented cases of various arrhythmias with fatal outcomes have been reported. We report a case of self-medication with 'tincture of aconite' resulting in severe bradycardia, reversible panconduction defect evidenced by sinus inactivity, atrioventricular dissociation with idiojunctional rhythm and left bundle branch block pattern resulting in hypotension and syncope.

The role of life events in short term metabolic control of non-insulin dependent diabetes mellitus.

For present study 2 groups were first chosen, each consisting of 50 NIDDM patients with matched age, sex and social class. One group (i.e.

Relationship between lower serum cholesterol level and psychiatric disorders.

The study applies the General Health Questionnaire (GHQ-60) to 50 consecutive patients attending Psychiatry-O.P.D.