20 results match your criteria: "Caffeine-Related Psychiatric Disorders"
Exploring the Potential Impact of GLP-1 Receptor Agonists on Substance Use, Compulsive Behavior, and Libido: Insights from Social Media Using a Mixed-Methods Approach.
Brain Sci
June 2024
Psychopharmacology, Drug Misuse, and Novel Psychoactive Substances Research Unit, University of Hertfordshire, College Lane Campus, Hatfield AL10 9AB, UK.
Article Synopsis
- The study investigates the impact of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) on various substance and behavioral addictions, including alcohol, nicotine, and compulsive shopping.
- Data was collected from online discussions on Reddit, focusing on posts between December 2019 and June 2023, where relevant comments were extracted using specific keywords related to GLP-1 RAs and addiction.
- Analysis revealed that a significant percentage of users reported reductions in alcohol (29.75%), caffeine (22.22%), and nicotine (23.08%) intake after starting GLP-1 RAs, while results for cannabis and other drugs were less conclusive.
Estimate the prevalence of daily caffeine consumption, caffeine use disorder, caffeine withdrawal and perceived harm in Iran: a cross-sectional study.
Sci Rep
April 2024
Department of Clinical Psychology, School of Behavioral Sciences, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Article Synopsis
- The study investigated the prevalence and effects of Caffeine Use Disorder (CUD) and caffeine consumption among 1,228 adults in Iran, finding significant rates of both conditions.
- Results revealed that 19.5% of participants had CUD and 46.62% experienced caffeine withdrawal, with higher prevalence in men compared to women.
- The study highlighted common caffeine-related harms such as cravings for sugar, insomnia, and dependence, indicating a need for evidence-based treatments for managing caffeine use issues in the Iranian population.
Caffeine-related genes influence anxiety disorders in children and adults with ADHD.
J Psychiatr Res
January 2022
Graduate Program in Biosciences, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil. Electronic address:
Article Synopsis
- ADHD and anxiety disorders often occur together, complicating treatment and increasing health issues.
- A study analyzed the genetic response to caffeine in children and adults with ADHD, finding a significant link between caffeine-related genes and anxiety disorders in both groups.
- However, these gene associations were not observed in a control group without ADHD, suggesting that caffeine-related genes may contribute specifically to anxiety disorders in individuals with ADHD.
The Neuroprotective Effects of Moderate and Regular Caffeine Consumption in Alzheimer's Disease.
Oxid Med Cell Longev
January 2022
The Key Laboratory for Special Medical Food Process in Hunan Province, Central South University of Forestry and Technology, Changsha, Hunan 410004, China.
Article Synopsis
- The rise in elderly Alzheimer's disease patients due to longer life expectancy raises significant scientific concerns, as effective treatments for AD are limited by unclear causes and mechanisms.
- Regular consumption of caffeine (200-500 mg/d) from coffee and tea may lower the risk of Alzheimer's and has potential therapeutic benefits.
- The paper reviews epidemiological studies on caffeine's impact on AD risk and recommends further research to determine optimal caffeine dosages and consumption patterns for slowing AD progression and treatment.
The Use and Impact of Cognitive Enhancers among University Students: A Systematic Review.
Brain Sci
March 2021
Psychopharmacology, Substance Misuse and Novel Psychoactive Substances Research Unit, School of Life and Medical Sciences, University of Hertfordshire, Hatfield AL10 9AB, UK.
Article Synopsis
- Cognitive enhancers (CEs), such as prescription drugs like methylphenidate and non-prescription options like caffeine, are increasingly being misused by university students as study aids, raising concerns about potential dependence.
- A systematic review of 1400 studies found that 48 were relevant, revealing that stimulant CEs are particularly popular among male students, often obtained from friends or online.
- The aim of the research is to better understand the awareness, perceptions, and impact of CEs in higher education institutions.
Caffeine consumption, toxicity, tolerance and withdrawal; shared genetic influences with normative personality and personality disorder traits.
Exp Clin Psychopharmacol
December 2021
Department of Mental Disorders.
Article Synopsis
- The study aimed to explore the genetic overlap between caffeine consumption and both healthy and disordered personality traits among adult twins in Norway.
- Data collected from interviews and self-reports revealed associations between caffeine use and various personality dimensions, particularly in traits related to personality disorders.
- Results indicated that while caffeine consumption has a genetic component, only a small to moderate percentage of its variance can be linked to shared genetic factors with normative and pathological personality traits.
Caffeine-related effects on cognitive performance: Roles of apoptosis in rat hippocampus following sleep deprivation.
Biochem Biophys Res Commun
January 2021
Basic Medical Sciences College, Hubei University of Chinese Medicine, Wuhan, 430065, China. Electronic address:
Article Synopsis
- - Caffeine acts as a stimulant that many people, especially those working shifts, use to boost alertness, but its effects combined with sleep deprivation (SD) on cognitive performance are not well understood.
- - Research found that sleep deprivation leads to cognitive issues and damage in the hippocampus, as well as increased neuron loss and apoptosis, which can be influenced by the levels of cAMP-PKA-CREB signaling.
- - Low doses of caffeine can enhance cognitive function post-sleep deprivation, while high doses may worsen cognitive impairment, suggesting that the amount of caffeine consumed after sleep loss is crucial for brain health.
Caffeine addiction: Need for awareness and research and regulatory measures.
Asian J Psychiatr
March 2019
Department of Psychiatry, Institute of Medical Sciences (IMS), Banaras Hindu University (BHU), Varanasi 221005, India. Electronic address:
Article Synopsis
- Caffeine consumption is rising among children and youth in India, but there is a lack of awareness about its addictive potential and harmful effects.
- This text highlights a case of caffeine dependence that leads to serious physical, psychological, and social consequences, along with predisposing personality traits and family history of psychosis.
- There is an urgent need for regulatory measures on caffeine products, improved public awareness, and further research to address the growing concerns related to caffeine use.
Arousal and the attentional network in panic disorder.
Hum Psychopharmacol
November 2014
Department of Psychiatry, University of Würzburg, Würzburg, Germany.
Article Synopsis
- Despite significant knowledge on panic disorder's neurobiology, a new model is needed that combines recent insights into the arousal system and higher cognitive functions.
- The review highlights evidence of dysfunction in key brain arousal systems, suggesting this could lead to panic disorder by triggering bodily symptoms and heightening awareness of those sensations through brain attention networks.
- A comprehensive model involving various neurochemical systems (norepinephrine, orexin, neuropeptide S, and adenosine) could help unify existing research on panic disorder's development.
Caffeine Withdrawal and Dependence: A Convenience Survey Among Addiction Professionals.
J Caffeine Res
June 2013
Department of Psychology, American University, Washington, District of Columbia.
Article Synopsis
- The study explored addiction professionals' beliefs about the clinical significance of caffeine withdrawal and dependence, as caffeine withdrawal was previously noted in the DSM-IV research appendix but not formally recognized as a disorder due to lack of research.* -
- A survey sent to members of six addiction-focused organizations revealed that while a large majority believe caffeine withdrawal is significant (73%) and that dependence could exist (58%), fewer support its inclusion in the DSM (48% and 44% respectively).* -
- Comments from respondents reflected concerns about psychiatric credibility due to potential stigmatization of common disorders, yet many urged for greater attention to caffeine-related issues and more research on the topic.*
"Clozapine makes me quite drowsy, so when I wake up in the morning those first cups of coffee are really handy": an exploratory qualitative study of excessive caffeine consumption among individuals with schizophrenia.
BMC Psychiatry
April 2014
Neami National, 247 - 249 Rosanna Road, 3084 Rosanna, VIC, Australia.
Article Synopsis
- * Through in-depth interviews with 20 participants categorized as 'moderate' or 'high' risk for caffeine use, researchers uncovered that cravings and previous positive experiences mainly drive caffeine consumption.
- * While many participants appreciated caffeine for its stimulating effects and social facilitation, some altered their consumption patterns based on anticipated negative consequences of use, highlighting a complex relationship with caffeine.
Acute caffeine administration effect on brain activation patterns in mild cognitive impairment.
J Alzheimers Dis
January 2015
Department of Mental Health and Psychiatry, University Hospitals of Geneva and Faculty of Medicine of the University of Geneva, Geneva, Switzerland.
Article Synopsis
- * It found that caffeine caused increased brain activation in specific areas for both groups, but MCI individuals exhibited a different, more widespread activation pattern, particularly in the prefrontal cortex and other regions.
- * The results suggest that individuals with MCI may shift their brain activation patterns posteriorly as a compensatory response to frontal lobe dysfunction when caffeine is consumed.
Energy drinks and caffeine-related adverse effects.
JAMA
January 2013
Infectious Disease Service, Department of Medicine, Infection Control, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA.
Article Synopsis
- The study aimed to find genetic variants linked to caffeine-induced insomnia and check if genes affected by caffeine are associated with this condition.
- Researchers conducted a large genome-wide association study using data from 2,402 coffee-drinking twins in Australia.
- Although no genetic variants met the significance threshold, some SNPs showed promising associations and the findings could shed light on the biological mechanisms of insomnia.*
Caffeinated energy drinks--a growing problem.
Drug Alcohol Depend
January 2009
Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.
Article Synopsis
- The energy drink market has exploded since Red Bull's introduction in 1987, with caffeine content varying significantly across brands—from 50 mg to 505 mg per serving.
- Regulation of energy drinks, especially in the U.S., is minimal, allowing aggressive marketing towards young males and potentially increasing risks of caffeine dependence and intoxication.
- Children and adolescents are particularly vulnerable to caffeine-related issues, and the rising trend of mixing energy drinks with alcohol raises further concerns about health risks and the potential for increased substance dependence.
Caffeine intake, toxicity and dependence and lifetime risk for psychiatric and substance use disorders: an epidemiologic and co-twin control analysis.
Psychol Med
December 2006
Virginia Institute of Psychiatric and Behavioral Genetics, Medical College of Virginia/Virginia Commonwealth University, Richmond, VA 23298-0126, USA.
Article Synopsis
- - Caffeine, despite being widely used, is linked to symptoms of toxicity and dependence, but its connection to psychiatric and substance use disorders is not well understood, especially in community settings.
- - A study involving over 3600 adult twins from the Virginia Twin Registry found that higher caffeine use and related issues were associated with various disorders like major depression and alcohol dependence, but these links were not significant among identical twins, suggesting that genetics and family environment play a crucial role.
- - The findings indicate that while there is a moderate association between caffeine consumption and disorders, the positive correlations likely stem from shared familial factors rather than direct causation between caffeine use and the development of mental health issues.
Caffeine deprivation state modulates coffee consumption but not attentional bias for caffeine-related stimuli.
Behav Pharmacol
November 2005
Department of Psychology, University of Portsmouth, Portsmouth, UK.
Article Synopsis
- Previous research indicated that caffeine deprivation affects how caffeine reinforces behavior and suggests an attentional bias towards caffeine-related stimuli among regular users.
- This study involved three experiments where participants were either given caffeine or a placebo, followed by tasks measuring their attentional bias towards caffeine-related words and subsequent coffee consumption.
- Results showed that while participants had an inherent attentional bias towards caffeine-related stimuli, their deprivation state did not influence this bias; however, those who were caffeine-deprived reported more drowsiness, headaches, and consumed more coffee.
Attentional bias for caffeine-related stimuli in high but not moderate or non-caffeine consumers.
Psychopharmacology (Berl)
September 2005
Department of Psychology, School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9Q6, UK.
Article Synopsis
- The study investigated whether caffeine consumers have an attentional bias toward caffeine-related words, similar to biases seen in other drug users.
- Sixteen individuals categorized as High, Moderate, and Non-consumers of caffeine participated in a dot-probe task after abstaining from caffeine overnight.
- Results showed that only High caffeine consumers displayed a significant bias for caffeine-related words, with their craving levels correlating to both attentional bias and caffeine intake, supporting theories of addiction.
Clinically significant pharmacokinetic interactions between dietary caffeine and medications.
Clin Pharmacokinet
August 2000
Department of Pharmacology and Psychiatry, Medical School, University of Extremadura, Badajoz, Spain.
Article Synopsis
- - Caffeine, commonly found in coffee, tea, and soft drinks, is the most widely consumed central nervous system stimulant, often viewed as safe despite its potential for abuse and significant health effects.
- - It can lead to serious complications like seizures and heart issues, particularly at high consumption levels or in combination with certain medications, as caffeine's metabolism can become saturated.
- - This saturation occurs when caffeine interacts with drugs that inhibit the CYP1A2 enzyme responsible for its breakdown, potentially resulting in increased toxicity and adverse effects.