Percutaneous endoscopic resection of a large fibroepithelial polyp in the renal pelvis using a resectoscope: a case report.

Background: Fibroepithelial polyp (FEP) in the renal pelvis is a rare benign tumor of the urinary tract. Treatment of such diseases varies from local resection to radical nephroureterectomy, either by open or endoscopic surgery. This study aims to show our successful experience in percutaneous endoscopic resection of FEP.

Brain aging rejuvenation factors in adults with genetic and sporadic neurodegenerative disease.

The largest risk factor for dementia is age. Heterochronic blood exchange studies have uncovered age-related blood factors that demonstrate 'pro-aging' or 'pro-youthful' effects on the mouse brain. The clinical relevance and combined effects of these factors for humans is unclear.

Does gene polymorphism affect the duration of orogastric tube use in moderate to late preterm neonates? A cross-sectional study in Indonesia.

Premature and low birth weight neonates often struggle with oral intake due to immaturity or respiratory distress. Forkhead box protein 2 gene () is predicted to influence oral feeding ability in newborns, but studies assessing the role of this gene in influencing oral feeding ability are limited. The aim of this study was to investigate the role of gene polymorphism, particularly single nucleotide polymorphism (SNP) rs17137124, on the duration of orogastric tube (OGT) use in moderate to late preterm neonates.

Assessing the value of computed tomography (CT) of the chest in the follow-up of patients with intrahepatic cholangiocarcinoma.

Background: Following tumor resection, imaging recommendation for the follow-up of patients with intrahepatic cholangiocarcinoma (IHCCA) include frequent chest, abdomen and pelvis computed tomography (CT) imaging. The appropriateness of additional imaging studies is usually derived from their clinical utility. The purpose of this work is to determine the value of chest CT imaging in the follow-up of patients with IHCCA.

A case report: spleen Epstein-Barr virus-positive inflammatory follicular dendritic cell sarcoma.

Background: Epstein-Barr virus-positive (EBV) inflammatory follicular dendritic cell sarcoma (IFDCS) is a rare stroma-derived neoplasm of lymphoid tissues. It typically involves the spleen and liver, and is often associated with the presence of EBV. Because of its nonspecific clinical and imaging findings, making a correct diagnosis at the time of initial diagnosis is challenging.

Development and nomogram prediction of early postoperative recurrence in hepatocellular carcinoma based on preoperative CT imaging radiomic features and serum features related to microvascular infiltration.

Background: Hepatocellular carcinoma (HCC) is characterized by high postoperative recurrence rates, and predicting early recurrence is crucial for improving clinical outcomes, yet remains challenging. Both preoperative computed tomography (CT) imaging radiomic features and serum biomarkers related to microvascular infiltration are important indicators of HCC prognosis. This study aimed to develop a nomogram model incorporating both preoperative CT radiomic features and serum biomarkers associated with microvascular infiltration to predict early postoperative recurrence in HCC patients.

Airway Mycobiota-Microbiota During Pulmonary Exacerbation of Cystic Fibrosis Patients: A Culture and Targeted Sequencing Study.

Background: The airways of patients with cystic fibrosis (pwCF) harbour complex fungal and bacterial microbiota involved in pulmonary exacerbations (PEx) and requiring antimicrobial treatment. Descriptive studies analysing bacterial and fungal microbiota concomitantly are scarce, especially using both culture and high-throughput-sequencing (HTS).

Objectives: We analysed bacterial-fungal microbiota and inter-kingdom correlations in two French CF centres according to clinical parameters and antimicrobial choices.

Efficacy of Open Reduction and Internal Fixation Assisted by Handheld Ultrasound Combined with 3D Printing Technology in Treating Multiple Rib Fractures.

Aim: This study aimed to explore the efficacy of open reduction and internal fixation assisted by handheld ultrasound combined with three-dimensional (3D) printing technology in treating multiple rib fractures.

Methods: We retrospectively analyzed the clinical data from 84 patients affected with multiple rib fractures admitted to our hospital between August 2022 and April 2024. After excluding four cases, 80 cases were included in this study.

A Novel Ensemble Approach for Rib Fracture Detection and Visualization using CNNs and Grad-CAM.

Aim: This study aimed to develop a reliable and efficient system for predicting and locating rib fractures in medical images using an ensemble of convolutional neural networks (CNNs).

Methods: We employed five CNN architectures-Visual Geometry Group Network 16 (VGG16), Densely Connected Convolutional Network 169 (DenseNet169), Inception Version 4 (Inception V4), Efficient Network B7 (EfficientNet-B7), and Residual Network Next 50 layers (ResNeXt-50)-trained on a dataset of 840 grayscale computed tomography (CT) scan images in .jpg format collected from 42 patients at a local hospital.

Post-transplant liver biopsies: a concise and practical approach for beginners.

Exposure to post-transplant liver biopsies varies among pathology residencies and largely depends on the institution's training program, particularly if the hospital has a liver transplant program. The interpretation of biopsies from transplanted livers presents its own set of challenges, even for those with a solid understanding of non-transplant medical liver biopsies. In this review, we aim to provide a succinct, step-by-step approach to help you interpret liver transplant biopsies.

Neurobiological fingerprints of negative symptoms in schizophrenia identified by connectome-based modeling.

Aim: As a central component of schizophrenia psychopathology, negative symptoms result in detrimental effects on long-term functional prognosis. However, the neurobiological mechanism underlying negative symptoms remains poorly understood, which limits the development of novel treatment interventions. This study aimed to identify the specific neural fingerprints of negative symptoms in schizophrenia.

[Clinical case : Prevascular mediastinal mass].

In the event of a prevascular mediastinal mass, knowledge of the anatomy and content of the mediastinum is an essential prerequisite to establish a differential diagnosis. The «4T» rule is applicable because it is a simple and effective mnemonic. It groups together; thyroid goiter, terrible lymphoma, teratoma and thymoma.

Heads and Tails: Comparative Osteology of Nearctic Dipsadid Snakes.

Although numerous studies have addressed some aspects of the cranial osteology of Nearctic dipsadid species, only the species within the genera Heterodon and Carphophis have a formal published description of their skull. Similarly, vertebral data on such species are extremely scarce, and most of the available literature is focused on fossils. Such group has a complex phylogenetic history, being recovered as monophyletic or nonmonophyletic depending on the approach.

Managing Chyle Leakage Following Right Retroperitoneoscopic Adrenalectomy: A Case Study.

BACKGROUND Surgery involving the right retroperitoneum can result in lymphatic (chylous) leakage from the cisterna chyli located anterior to the L1 and L2 vertebra or from lymph node dissection. This report describes a 46-year-old woman with retroperitoneal lymphatic (chylous) leak following right adrenalectomy for a nonfunctional adrenal adenoma. CASE REPORT A 46-year-old woman presented with a medical history of hypertension.

Evaluating the impact of stratification on the power and cross-arm balance of randomized phase 2 clinical trials.

Background/aims: Randomized clinical trials often use stratification to ensure balance between arms. Analysis of primary endpoints of these trials typically uses a "stratified analysis," in which analyses are performed separately in each subgroup defined by the stratification factors, and those separate analyses are weighted and combined. In the phase 3 setting, stratified analyses based on a small number of stratification factors can provide a small increase in power.

Augmented Reality Navigation System Enhances the Accuracy of Spinal Surgery Pedicle Screw Placement: A Randomized, Multicenter, Parallel-Controlled Clinical Trial.

Objective: The pedicle screw insertion technique has evolved significantly, and despite the challenges of precise placement, advancements like AR-based surgical navigation systems now offer enhanced accuracy and safety in spinal surgery by integrating real-time, high-resolution imaging with virtual models to aid surgeons. This study aims to evaluate the differences in accuracy between novel AR-guided pedicle screw insertion and conventional surgery techniques.

Methods: A randomized controlled trial was conducted from March 2019 to December 2023 to compare the efficacy of AR-guided pedicle screw fixation with conventional freehand surgery using CT guidance.

Developing an automatic treatment record review system for quality assurance of patient treatment delivery in radiation therapy.

Background And Purpose: Treatment record contains most of information related to treatment plan delivery in radiation therapy. Reviewing treatment record is an important quality assurance (QA) task for safety and quality of patient treatments. This task is usually performed by senior medical physicists.

Location or size? A finite element analysis study of necrotic lesion impact on femoral head collapse.

Background: The location and size of necrotic lesions are important factors for collapse, The preserved angles (PAs) are divided into anterior preserved angle (APA) and lateral preserved angle (LPA), which could accurately measure the location of necrosis lesion. We used them to evaluate the effect of the location and size of necrotic lesions on collapse by finite element analysis, to offer a framework for evaluating the prognosis of osteonecrosis of the femoral head (ONFH) in clinical settings.

Methods: 3 left hip models were constructed based on CT data.

Latent class analysis of the capacity of countries to manage diabetes and its relationship with diabetes-related deaths and healthcare costs.

Background: The prevalence of diabetes is escalating globally, underscoring the need for comprehensive evidence to inform health systems in effectively addressing this epidemic. The purpose of this study was to examine the patterns of countries' capacity to manage diabetes using latent class analysis (LCA) and to determine whether the patterns are associated with diabetes-related deaths and healthcare costs.

Methods: Eight indicators of country-level capacity were drawn from the World Health Organization Global Health Observatory dataset: the widespread availability of hemoglobin A1C (HbA1c) testing, existence of diabetes registry, national diabetes management guidelines, national strategy for diabetes care, blood glucose testing, diabetic retinopathy screening, sulfonylureas, and metformin in the public health sector.

Combining theory and usability testing to inform optimization and implementation of an online primary care depression management tool.

Background: The 'Ottawa Depression Algorithm' is an evidence-based online tool developed to support primary care professionals care for adults with depression. Uptake of such tools require provider behaviour change. Identifying issues which may impact use of an innovation in routine practice (i.

Clinical and imaging features of co-existent pulmonary tuberculosis and lung cancer: a population-based matching study in China.

Background: Co-existent pulmonary tuberculosis and lung cancer (PTB-LC) represent a unique disease entity often characterized by missed or delayed diagnosis. This study aimed to investigate the clinical and radiological features of patients diagnosed with PTB-LC.

Methods: Patients diagnosed with active PTB-LC (APTB-LC), inactive PTB-LC (IAPTB), and LC alone without PTB between 2010 and 2022 at our institute were retrospectively collected and 1:1:1 matched based on gender, age, and time of admission.

Treatment of posterolateral tibial plateau fractures through the articular line approach.

Background: Posterolateral tibial plateau fractures pose significant challenges for orthopedic surgeons due to the anatomical risks associated with the posterolateral approach. Despite numerous surgical techniques available, there lacks a consensus on the optimal approach.

Methods: Articular line incision approach was employed on 12 patients suffering from posterolateral tibial plateau fractures.

Preoperative CT lymph node size as a predictor of nodal metastasis in resectable Colon cancer: a retrospective study of 694 patients.

Purpose: This study aimed to investigate the efficacy of measuring lymph node size on preoperative CT imaging to predict pathological lymph node metastasis in patients with colon cancer to enhance diagnostic accuracy and improve treatment planning by establishing more reliable assessment methods for lymph node metastasis.

Methods: We retrospectively analyzed 1,056 patients who underwent colorectal resection at our institution between January 2004 and March 2020. From this cohort, 694 patients with resectable colon cancer were included in the study.

Removal of an entrapped guidewire by excimer laser coronary angioplasty in patients with chronic total occlusion intervention.

Guidewire entrapment (GE) is a rare complication that warrants complex interventions or surgical procedures. Here, we report the removal of an entrapped guidewire using excimer laser coronary angioplasty (ELCA) in a case of chronic total occlusion (CTO). Plaque tissue trapped with the guidewire was also removed.