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627 results match your criteria: "CSIR-Central Leather Research Institute[Affiliation]"
Org Lett
December 2024
Indian Institute of Science Education and Research Thiruvananthapuram, Kerala-695 551, India.
A series of dithienopyrrole (DTP) embedded BODIPYs were synthesized and structurally characterized. These BODIPYs have strong absorption in the green region and broad emission in the red region with a large Stokes shift ranging from 3100 to 4200 cm. Interestingly, all three BODIPYs show intramolecular charge transfer interaction (ICT).
View Article and Find Full Text PDFBiomater Sci
December 2024
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India.
Pathogenic bacterial growth at wound sites, particularly , poses a serious threat during trauma. Delayed treatment can lead to increased inflammation and severe tissue damage. In this study, a chitosan cross-linked polycationic peptide-conjugated graphene-silver (CGrAP) nanocomposite hydrogel film was developed as an antibacterial wound dressing to treat infections.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, Uttar Pradesh, India; Centre for Analysis, Testing, Evaluation & Reporting Services (CATERS), CSIR-Central Leather Research Institute (CSIR-CLRI), Adyar, Chennai 600020, Tamil Nadu, India.
Existing polystyrenic and polyolefinic packaging foams are non-biodegradable, and persist in the environment for hundreds of years. Gelatin foams are an interesting alternative, given their biodegradability, biocompatibility, solution-based processability, low cost, and non-toxicity. However, current methods for preparing gelatin foams, such as freeze-drying, microfluidic foaming, and batch foaming, are not suitable for high-volume production.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
December 2024
Inorganic and Physical Chemistry Department, CSIR - Central Leather Research Institute (CLRI), Chennai, Tamil Nadu, India, 600020.
To overcome the stringent regulations in the usage of chromium salts and dye-rich effluent let out by the tanning industry, a sustainable way of leather processing has been demonstrated utilizing amine pendant metal-organic frameworks (MOF) UiO-66-NH along with glyoxal. It was found that an offer of 8% (w/w) MOF along with 6% (w/w) glyoxal increased the shrinkage temperature of the leathers to 89 ± 2 °C with exhaustion of MOF up to 84.3 ± 1.
View Article and Find Full Text PDFChem Asian J
December 2024
Organic and Bio-Organic Chemistry laboratory, CSIR-Central Leather Research Institute (CSIR-CLRI), Chennai, 600020, India.
The efficient pentaflurophenol-catalyzed Pictet-Spengler cyclization was carried out which led to the formation of spirobenzazepinoindole. This article examines the methods and modifications of Pictet-Spengler cyclization in the synthesis of intricate organic compounds, emphasizing its significance in drug discovery and development. This reaction generally entails the condensation of an amine with an aldehyde or ketone, succeeded by an intramolecular cyclization step catalyzed by pentafluorophenol, an alternate for metal-mediated catalysts due to its facile characteristics which render it an invaluable asset in organic synthesis and catalysis.
View Article and Find Full Text PDFLangmuir
December 2024
Organic & Bioorganic Chemistry Laboratory, Council of Scientific and Industrial Research (CSIR) - Central Leather Research Institute (CLRI), Adyar, Chennai 600020, India.
Controlling the minimum gelation concentration (MGC) of low molecular weight (LMW) hydrogelators is a key for modulating gel properties, such as mechanical strength, viscoelasticity, and stability, which are crucial for applications ranging from drug delivery to tissue engineering. However, tweaking the MGC under specific conditions, such as pH and/or temperature, poses a considerable challenge. Herein, we varied the ionic strength of buffer solutions using NaCl for several LMW hydrogelators, including Fmoc-Phe, Fmoc-Tyr, Fmoc-Trp, Fmoc-Met, and Fmoc-Cha, and assessed their gelation efficiency at pH 7.
View Article and Find Full Text PDFRSC Adv
November 2024
Advanced Materials Laboratory, CSIR-Central Leather Research Institute Sardar Patel Road, Adyar Chennai 600020 India
Despite the increased research and scholarly attention on two-dimensional (2D) materials, there is still a limited range of practical applications for these materials. This is because it is challenging to acquire properties that are usually obtained by experiments or first-principles predictions, which require substantial time and resources. Descriptor-based machine learning models frequently require further density functional theory (DFT) calculations to enhance prediction accuracy due to the intricate nature of the systems and the constraints of the descriptors employed.
View Article and Find Full Text PDFChem Asian J
November 2024
Department of Chemistry, Indian Institute of Technology Madras, Chennai, 600036, India.
The increasing global energy demand and environmental pollution necessitate the development of alternative, sustainable energy sources. Hydrogen production through electrochemical methods offers a carbon-free energy solution. In this study, we have designed novel boron nitride analogues (BNyne) and investigated their stability and electronic properties.
View Article and Find Full Text PDFLangmuir
November 2024
Organic and Bioorganic Chemistry Laboratory, Council of Scientific and Industrial Research (CSIR) - Central Leather Research Institute (CLRI), Adyar, Chennai 600020, India.
Biomacromolecules
November 2024
Polymer Science & Technology Unit, Advanced Materials Laboratory, CSIR-Central Leather Research Institute (CSIR-CLRI) Sardar Patel Road, Adyar, Chennai 600 020, India.
Hydrogels are indispensable for a variety of applications. Conventional biomaterial-based hydrogels, typically made from proteins or polysaccharides, often suffer from high costs, poor mechanical properties, and limited chemical functionality for modification. In this work, we present a novel hydrogel developed from modified castor oil, which is a renewable and cost-effective resource.
View Article and Find Full Text PDFJ Mech Behav Biomed Mater
December 2024
Inorganic and Physical Chemical Laboratory, CSIR-Central Leather Research Institute (CSIR-CLRI), Adyar, Chennai 600 020, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India. Electronic address:
Tuned assembly of collagen has tremendous applications in the field of biomedical and tissue engineering owing to its targeted biological functionalities. In this study, ionic liquids choline dihydrogen citrate (CDHC) and diethyl methyl ammonium methane sulfonate (AMS) have been used to regulate the self-assembly of collagen at its physiological pH by probing the assembled systems at certain concentration ratios of ionic liquids and the systems were studied using various characterization methods. Due to interaction with collagen, choline dihydrogen citrate causes delay in the collagen fibrillisation process showing no binding interactions with collagen.
View Article and Find Full Text PDFMacromol Biosci
October 2024
Department of Biochemistry and Biotechnology, CSIR- Central Leather Research Institute, Chennai, 600020, India.
J Fluoresc
October 2024
Organic and Bioorganic Chemistry Laboratory, CSIR-Central Leather Research Institute, Adyar, Chennai, 600020, India.
A novel imidazo[1,2-a]pyridine derivative probe (R) was designed, synthesized, and characterized via various characterization techniques, such as ESI-MS, H NMR, C NMR, and Dept-135 NMR. The data obtained from single-crystal XRD reveal that probe R has a coplanar configuration and is part of the monoclinic crystal system, designated the P2(1)/n space group. The fluorescence of (R) is further enhanced by silver (I) ions.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
October 2024
Catalysis Science Laboratory, CSIR-Central Leather Research Institute, Adyar, Chennai, 600 020, India.
Phys Chem Chem Phys
October 2024
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India.
The realm of atomic catalysts has witnessed notable advancements; yet, the predominant focus remains on single atomic catalysts (SACs). The exploration and successful implementation of dual atomic catalysts (DACs) pose intricate challenges, primarily concerning thermodynamic stability and optimal metallic composition. To address these issues, we present a comprehensive theoretical investigation of α-2 graphyne (GPY)-based DACs, synthesized in-house with a keen focus on formation stability.
View Article and Find Full Text PDFChem Asian J
December 2024
Organic and Bio-Organic Chemistry laboratory, CSIR-Central Leather Research Institute (CSIR-CLRI), Chennai, 600020, India.
The syntheses of novel spirobenzazepinoindole derivatives has been achieved through a highly efficient and synthetic route. The approach involves a two-step reaction, utilizing indole derivatives, 2-amino benzyl alcohol, and ninhydrin as key starting materials under mild reaction conditions. The reaction proceeds via a sequential cascade process involving cyclization, condensation and spiro-annulation, leading to the formation of the spirobenzazepinoindole core structure in good to excellent yields.
View Article and Find Full Text PDFInt J Biol Macromol
November 2024
Department of Chemistry, Anna University, Chennai 600 025, India.
The objective of this study is to create high-performance nano biocomposites by utilizing unsaturated polyester resin (PE) reinforced with pre-treated short (2 cm) lengthened sunn hemp (SH) fibers and by incorporating 5 % nanoclay (hydrophilic bentonite) through the compression molding technique. The addition of 5 % nanoclay to the biocomposite significantly increased the flexural strength by approximately 165 % for HO-treated SH fiber and 148 % for KMnO-treated SH fiber, when compared to untreated fibers. This enhancement was achieved through phase separation, intercalation, and exfoliation between the SH fibers, polyester resin (PE), and 5 % nanoclay.
View Article and Find Full Text PDFChemMedChem
November 2024
Inorganic and Physical Chemistry Laboratory, CSIR-Central Leather Research Institute, Chennai, 600020, Tamil Nadu, India.
Cancer, a deadly and constantly evolving disease, has always been difficult to treat due to the complexity of the tumor microenvironment (TME). Cancer nanomedicines are proving to be a much better alternative for treatment due to their stability and ability to provide an efficient targeted therapy. An amorphous alloy bimetallene with an introduction of 2 % tensile strain with photothermal multiple enzyme-like catalytic activity is being presented here that functions as a TME-responsive nanozyme.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
January 2025
Organic and Bioorganic Chemistry Laboratory, CSIR-Central Leather Research Institute, Adyar, Chennai 600020, India; Academy of Scientific and Innovative Research (AcSIR), CSIR-Central Leather Research Institute, Adyar, Chennai 600020, India. Electronic address:
A new 1,8-naphthalimide derivative (probe 1) adopts V-shaped structure, emits fluorescence and displays the Mie effect and aggregation-induced emission (AIE). Selective interactions of thiophilic Ag and Hg ions (10 µM) with 1 (10 µM) resulted in AIEs at 499 and 521 nm, respectively. Both Ag and Hg induce the formation of 1:2 complexes with 1, leading to the formation of AIE active aggregates with an average size of 423 and 198 nm, respectively.
View Article and Find Full Text PDFInt J Biol Macromol
November 2024
Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai 600036, India. Electronic address:
We have fabricated and characterized novel bioactive nanocomposite interpenetrating polymer network (IPN) scaffolds to treat bone defects by loading mesoporous silica nanoparticles (MSNs) into blends of Konjac glucomannan, polyvinyl alcohol, and polycaprolactone. By loading MSNs, we developed a porous nanocomposite scaffold with mechanical strengths comparable to cancellous bone. In vitro cell culture studies proved the cytocompatibility of the nanocomposite scaffolds.
View Article and Find Full Text PDFJ Phys Chem A
September 2024
Department of Chemistry, Ashoka University, Sonipat 131029, Haryana, India.
Designing an efficient and cost-effective catalyst for ammonia borane () dehydrogenation remains a persistent challenge in advancing a hydrogen-based economy. Transition metal complexes, known for their C-H bond activation capabilities, have emerged as promising candidates for dehydrogenation. In this study, we investigated two recently synthesized C-H activation catalysts, (Co-dinitrate complex) and (Ni-nitrate complex), and demonstrated their efficacy for dehydrogenation.
View Article and Find Full Text PDFChemphyschem
December 2024
Polymer Science and Technology, CSIR-Central Leather Research Institute, Adyar, Chennai, 600020, India.
A Model mesogen and its symmetrical Dimer made up of phenyl benzoate core unit are investigated by C NMR spectroscopy. The existence of layer order in smectic A and smectic C phases of Dimer mesogen is established by powder X-ray diffraction. The chemical shift anisotropy (CSA) tensors of Model mesogen are determined by 2D separation of undistorted powder patterns by effortless recoupling (SUPER) experiment and are utilized for calculating the order parameters employing the alignment-induced chemical shifts (AIS).
View Article and Find Full Text PDFChem Sci
August 2024
Inorganic and Physical Chemistry Laboratory, CSIR-Central Leather Research Institute Chennai-600020 Tamil Nadu India
Nature has endowed us with some complex enzymes capable of utilizing proteins as their substrates to generate functional proteins through post-translational modification. However, nanozymes' interplay with proteins as substrates is scarce, with their chemistry predominantly established using only small molecule substrates, featuring a significant gap in this area. Due to the huge prospects of nanozymes in biotechnological and therapeutic interventions, studies establishing the unexplored roles of nanozymes in the biological environments and their interplay beyond small molecule substrates warrant immediate attention.
View Article and Find Full Text PDFMitochondrion
September 2024
Microbiology Division, CSIR - Central Leather Research Institute, Adyar, Chennai 20, Tamil Nadu, India. Electronic address:
Authentication of true (genuine) cow leathers is in high demand to promote merchandise and economic growth. The present study employs RT-PCR-based TaqMan assay to facilitate the identification. Species-specific primers and probes were designed utilizing the existing NCBI data on mitochondrial DNA (mtDNA) genes, particularly the cytochrome b region (Cyt b).
View Article and Find Full Text PDFActa Trop
October 2024
Microbiology Laboratory, CSIR- Central Leather Research Institute, Adyar, Chennai, 600020, India. Electronic address:
The Siddha system of medicine (SSM) is the oldest medical science practised in the ancient period of the southern part of India and Sri Lanka. Many formulations were described for wound healing in the SSM, with specific diagnostic differentiation in the Siddha literature. Most preparations for wound healing were available in the form of oil-based formulations, especially for external usage.
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