Metabolite Profiling, Biological and Molecular Analyses Validate the Nutraceutical Potential of Green Seaweed for Human Health.

Seaweeds have proven to be nutrient-dense and are rich in antioxidants, like phenolics, flavonoids, and other essential metabolites that help to provide their medicinal benefits. Non-targeted metabolite profiling of the tropical green seaweed s showed the presence of numerous groups of contents, including sugars, essential amino acids, and fatty acids. Targeted metabolite profiling using HPLC identified 17 amino acids.

Strategic design of VO encased in N-doped carbon as an efficient electrocatalyst for the nitrogen reduction reaction in neutral and acidic media.

Electrocatalytic nitrogen fixation to ammonia (NH), a precursor for fertilizer production and a promising energy carrier, has garnered widespread interest as an environment-friendly and sustainable alternative to the energy-intensive fossil-feedstock-dependent Haber-Bosch process. The large-scale deployment of this process is contingent on the identification of inexpensive, Earth-abundant systems that can operate efficiently, irrespective of the electrolyte pH for the selective production of NH. In this regard, we discuss the scalable synthesis of VO anchored on N-doped carbon (VO2@CN), and its applicability as a robust electrocatalyst for the nitrogen reduction reaction (NRR).

Deciphering the potential of extract: metabolic profiling and pathway analysis of groundnut () in response to extract and .

Unlabelled: Seaweed extracts have enormous potential as bio-stimulants and demonstrated increased growth and yield in different crops. The presence of physiologically active component stimulate plant stress signaling pathways, enhances growth and productivity, as well as serve as plant defense agents. The seaweed extracts can reduce the use of chemicals that harm the environment for disease management.

Diverse structural reactivity patterns of a POCOP ligand with coinage metals.

We have utilised the 4,6-di--butyl resorcinol bis(diphenylphosphinite) (POCOP) ligand for exploring its coordination ability towards group 11 metal centres. The treatment of the bidentate ligand 1 with various coinage metal precursors afforded a wide range of structurally diverse complexes 2-12, depending upon the metal precursors used. This furnishes several multinuclear Cu(I) complexes with dimeric (2) and tetrameric cores (3, 4, and 5).

Micropores in Hollow Organic Cage Nanocapsule as a Size Exclusion Gate: Cage Entrapped Pd(II)-Catalyst for Efficient Cross-Coupling Reaction.

Hollow porous organic capsules (HPOCs) with an entrapped active catalyst have nanosized cavities, providing the benefits of a nanoreactor, as well as separation of the catalysts from the reaction medium via pores acting as a size-exclusion gate. Such purpose-built HPOCs with desired molecular weight cutoffs offer the advantages of semipermeable membrane separation and a sustainable chemical process that excludes energy-extensive separation. Here, we report a newly synthesized HPOC with an entrapped Pd(PPh)Cl as the catalyst for demonstrating a Suzuki-Miyaura coupling reaction as a proof of concept.

H-Glass Supported Hybrid Gold Nano-Islands for Visible-Light-Driven Hydrogen Evolution.

Flat panel reactors, coated with photocatalytic materials, offer a sustainable approach for the commercial production of hydrogen (H) with zero carbon footprint. Despite this, achieving high solar-to-hydrogen (STH) conversion efficiency with these reactors is still a significant challenge due to the low utilization efficiency of solar light and rapid charge recombination. Herein, hybrid gold nano-islands (HGNIs) are developed on transparent glass support to improve the STH efficiency.

Highly Selective and Scalable Molecular Fluoride Sensor for Naked-Eye Detection.

Fluoride is widely present in nature, and human exposure to it is generally regarded as inevitable. High levels of fluoride intake induce acute and chronic illnesses. To reduce potential harm to the general public, it is essential to create selective fluoride detectors capable of providing a colorimetric response for naked-eye detection without the need for sophisticated equipment.

Organocatalyzed Enantio- and Diastereoselective Formal Domino 1,3-Dipolar Cycloaddition/Rearrangement: Synthesis of Chiral Pyrrolo-thiazine-2-carbaldehydes.

An efficient approach for the synthesis of chiral pyrrolo[1,2-][1,4]thiazine-2-carbaldehydes is achieved via formal 1,3-dipolar cycloaddition/rearrangement reactions of benzothiazolium salt and α,β-unsaturated aldehydes, utilizing an asymmetric organocatalyst. This process results in the formation of fluorescent, highly enantioenriched chiral molecules with three contiguous stereogenic centers, one of which is a chiral quaternary center, with excellent yields and enantio- and diastereoselectivity. A computational study demonstrated the understanding of the reaction mechanism.

Design and Fabrication of Broad-Spectrum Antimicrobial Porous Metallo-Polymeric Microsphere for Water Disinfection.

An expedient and efficient approach is used to synthesize a new class of metallo-polymeric microspheres (MPMs) as antimicrobials to succumb the wide range of bacteria from water. Three types of MPMs, that is, poly[Silver (I)-methacrylate-co-methylmethacrylate] (pAgMA), poly[Copper (II)-methacrylate-co-methyl methacrylate] (pCuMA), and poly[Nickel (II)-methacrylate-co-methylmethacrylate] (pNiMA), are prepared via radical suspension polymerization technique in 3D shape with porous texture. The structural and morphological characterization of the prepared microspheres are examined by analytical techniques.

Synthesis, characterization, and crystal structure of 2-(2-azido-phen-yl)-3-oxo-3-indole 1-oxide.

An attempt to explore the reactivity of the nitro group in the presence of gold catalysis in comparison to the azide group yielded intriguing results. Surprisingly, only the nitro group exhibited reactivity, ultimately giving rise to the formation of the title isatogen, CHNO. In the crystal structure, weak C-H⋯O hydrogen bonds and π-π stacking inter-actions link the mol-ecules.

Thermo-chemical behaviour of Dunaliella salina biomass and valorising their biochar for naphthalene removal from aqueous rural environment.

Thermo-chemical behavior of a microalgal biomass; Dunaliella salina was investigated through thermo-gravimetric analyses. Fully-grown D. salina biomass were subjected for biochar conversion using pyrolytic treatment at three distinct heating rates such as 2.

Development of masked silica tanning system for sustainable leather production.

Amid mounting pressure on the long-term recyclability of chromium in tanned leather and the associated environmental hazards, the quest for an alternative, cleaner tanning system has gained tremendous momentum. In this context, our study explores the remarkable potential of silicates as a versatile platform for skin/hide tanning, circumventing the inherent risks and ecological threats posed by chromium exposure and leaching. We present an alternative approach of using a silica-based tanning system, employing a Taguchi model, to optimize a masked silica (MaSil) tanning product/process for achieving effective collagen stabilization.

Do Ionic Liquids Exhibit the Required Characteristics to Dissolve, Extract, Stabilize, and Purify Proteins? Past-Present-Future Assessment.

Proteins are highly labile molecules, thus requiring the presence of appropriate solvents and excipients in their liquid milieu to keep their stability and biological activity. In this field, ionic liquids (ILs) have gained momentum in the past years, with a relevant number of works reporting their successful use to dissolve, stabilize, extract, and purify proteins. Different approaches in protein-IL systems have been reported, namely, proteins dissolved in () neat ILs, () ILs as co-solvents, () ILs as adjuvants, () ILs as surfactants, () ILs as phase-forming components of aqueous biphasic systems, and () IL-polymer-protein/peptide conjugates.

Chromone-Based Cd(II) Fluorescent Coordination Polymer Fabricated to Study Optoelectronic and Explosive Sensing Properties.

Here, electrical conductivity and explosive sensing properties of multifunctional chromone-Cd(II)-based coordination polymers (CPs) (-) have been explored. The presence of different pseudohalide linkers, thiocyanate ions, and dicyanamide ions resulted in 1D and 3D architecture in the CPs. Thin film devices developed from CPs - (complex-based Schottky devices, , , , and , respectively) showed semiconductor behavior.

Targeted Isolation of Antibiofilm Compounds from Halophytic Endophyte 7NPB-3B Using LC-HR-MS-Based Metabolomics.

The discovery of new natural products has become more challenging because of the re-isolation of compounds and the lack of new sources. Microbes dwelling in extreme conditions of high salinity and temperature are huge prospects for interesting natural metabolites. In this study, the endophytic bacteria 7NPB-3B isolated from the halophyte was screened for its biofilm inhibition against methicillin-resistant (MRSA).

Are Hansen solubility parameters relevant in predicting the post-treatment effect on polyamide-based TFC membranes?

This study investigates the impact of solvent post-treatment on polyamide-based thin film composite (TFC) membranes, specifically examining the effect on commercial nanofiltration (NF) and reverse osmosis (RO) membranes. NaSO rejection and increase in pure water permeance (PWP) were considered as the output parameters. The disparity in Hansen solubility parameters (HSP) between the post-treatment solution and the polyamide layer of the TFC membrane, denoted by Ra, is well adapted to understand the enhancement in water permeance through the membranes upon treatment.

Revealing the key structural features promoting the helical conformation in algal polysaccharide carrageenan in solution.

Carrageenans are industrially important polysaccharides with tunable viscoelastic and gelation properties. The function of polysaccharide depends on its conformation and chemical composition. However, the solution conformations of carrageenans are highly debated, and the structure-function relationship remains elusive.

Differential regulation of key triterpene synthase gene under abiotic stress in Withania somnifera L. Dunal and its co-relation to sterols and withanolides.

Withania somnifera (Ashwagandha), is one of the most reputed Indian medicinal plants, having immense pharmacological activities due to the occurrence of withanolides. The withanolides are biosynthesized through triterpenoid biosynthetic pathway with the involvement of WsCAS leading to cyclization of 2, 3 oxidosqualene, which is a key metabolite to further diversify to a myriad of phytochemicals. In contrast to the available reports on the studies of WsCAS in withanolide biosynthesis, its involvement in phytosterol biosynthesis needs investigation.

The role of LMG S-31876 in treating IBS-diarrhea.

Introduction: Irritable bowel syndrome (IBS) is a common gastrointestinal condition. Some studies have shown the efficacy of probiotics in the treatment of irritable bowel syndrome (IBS). LMG S-31876 has been marketed as a dietary ingredient, but to date, its efficacy in diarrhea-predominant irritable bowel syndrome (IBS) condition has not been clinically elucidated.

Epitaxially Grown Mechanically Robust 2D Thin Film of Secondary Interactions Led Molecularly Woven Material.

Molecularly woven materials with striking mechanical resilience, and 2D controlled topologies like textiles, fishing nets, and baskets are highly anticipated. Molecular weaving exclusively apprehended by the secondary interactions expanding to laterally grown 2D self-assemblies with retained crystalline arrangement is stimulating. The interlacing entails planar molecules screwed together to form 2D woven thin films.

Fluorescent Carbon Dots: Aggregation-Induced Emission Enhancement, Application as Probe for CN and CrO, Sensing Strips and Bio-imaging Agent.

Fluorescent carbon dots (Trp-CDs) were prepared using tryptophan as precursor and were characterized on the basis of elemental analysis, powder-XRD, IR, Raman spectroscopy, C-NMR, UV-Vis, fluorescence and TEM. Trp-CDs exhibit poor fluorescence in 100% water but showed strong Aggregation Induced Emission (AIE) in ethanol and higher alcohols. The anion sensing study of Trp-CD revealed that it selectively detects CN and CrO and from fluorescence quenching titration study, quenching constant, LOD and range of detection were evaluated.

Molten salt mediated single-step synthesis of reusable nanostructured CaTiO for the removal and recovery of Sr: A potential adsorbent for the contaminated water bodies.

The facile synthesis approach for the adsorbent preparation and recyclability during decontamination of radioactive pollutants is a significant concern in water treatment. The objective of this study is to, synthesis via solid-state reaction of the nanostructured CaTiO for the removal and recovery of strontium (Sr) from the various water sources. The influence of the adsorption-dependent parameters including, initial concentration, adsorbent dose, pH, contact time and co-existing ions interference were investigated.

Novel protocol for fouling detection of reverse osmosis membrane based on methylene blue colorimetric method by image processing technique.

In the current study, a novel methylene blue (MB)-based colorimetric method for a quick, inexpensive, and facile approach for the determination of fouling intensity of reverse osmosis (RO) membrane has been reported. This technique is based on the interaction of MB with the organic foulants and shows the corresponding change in the colour intensity depending on the severity of fouling. The organic foulants, such as albumin, sodium alginate, and carboxymethyl cellulose (CMC), were chosen as model foulants, and the membranes were subjected to foul under extreme fouling conditions.

Eco-friendly and sustainable process for recovery of sulfate from paper mill mixed salt: Recycling of sulfate for dye fixation process.

Paper mill Electrostatic Precipitator (ESP) ash contains a mixture of alkali metal chloride (34.2 %) and sulfate (84.2 %) which has serious negative effects on the environment and makes it more expensive and constrained to dispose ESP ash.