Demonic axe-like conjugated alkynes in combating microbes.

A new series of disubstituted alkynes was obtained by microwave induced internal splitting of the corresponding β-oxo-alkylidenetriphenylphosphoranes. The antimicrobial potential of these conjugated alkynes and phosphoranes was assayed in vitro against three Gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis, Staphylococcus epidermidis), three Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae) and five fungal strains (Aspergillus niger, Candida albicans, Aspergillus flavus, Candida rugosa, Saccharomyces cerevisiae). The 3-pyridylalkyne derivatives viz.

Chronic unpredictable stress (CUS)-induced anxiety and related mood disorders in a zebrafish model: altered brain proteome profile implicates mitochondrial dysfunction.

Anxiety and depression are major chronic mood disorders, and the etiopathology for each appears to be repeated exposure to diverse unpredictable stress factors. Most of the studies on anxiety and related mood disorders are performed in rodents, and a good model is chronic unpredictable stress (CUS). In this study, we have attempted to understand the molecular basis of the neuroglial and behavioral changes underlying CUS-induced mood disorders in the simplest vertebrate model, the zebrafish, Danio rerio.

Gas phase bio-filter for the removal of triethylamine (TEA) from air: microbial diversity analysis with reference to design parameters.

Biotic (packed bio-filter; PBF) and abiotic (packed filter; PF) studies were carried out on two similar 2L gas phase filters for the removal of triethylamine (TEA) at inlet concentration in the range of 250-280 ppmV. Removal efficiency (RE) of PBF remained in the range of 90-99% during the stable period of operation (170 days) whereas RE of PF dropped gradually to 10% in a span of 90 days. Five different bacterial species viz; Aeromonas sp.

Influence of graphite flake addition to sediment on electrogenesis in a sediment-type fuel cell.

Graphite flakes at levels of 5%, 15%, 20% and 40% (weight per sediment volume) were added to lake bed sediment and electrogenesis in a sediment-type fuel cell was evaluated. Addition of graphite flakes by 20% to the sediment showed higher electrogenic activity of the fuel cell (578mV; 0.37mW) compared to control (304mV; 0.