1,863 results match your criteria: "COMSATS Institute of information Technology[Affiliation]"

Biosorption of iron ions through microalgae from wastewater and soil: Optimization and comparative study.

Chemosphere

February 2021

Beijing Key Laboratory for Bioengineering and Sensing Technology, Research Centre for Bioengineering and Sensing Technology, School of Chemistry and Biological Engineering, University of Science & Technology Beijing, 30 Xueyuan Road, Beijing, 100083, PR China; School of Biomedical Engineering, Health Science Centre, Shenzhen University Shenzhen, Guangdong, 518060, PR China. Electronic address:

Microalgae play a significant role in wastewater and soil-bioremediation due to their low-cost and eco-friendly nature. In this study, 21 strains of microalgae were evaluated during removal of iron Fe from aqueous solutions. Out of 21 strains, five strains (S.

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Flue gas contains high amount of low-grade heat and water vapor that are attractive for recovery. This study assesses performance of a hybrid of water scrubber and membrane distillation (MD) to recover both heat and water from a simulated flue gas. The former help to condense the water vapor to form a hot liquid flow which later used as the feed for the MD unit.

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The present study investigated the stability and efficacy of a biosurfactant produced by Klebsiella sp. KOD36 under extreme conditions and its potential for enhancing the solubilization and degradation of phenanthrene in various environmental matrices. Klebsiella sp.

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Molecular drug targets for scabies: a medicinal chemistry perspective.

Future Med Chem

December 2020

Department of Pharmacy, Comsats Institute of Information Technology, University Road, Abbottabad 22010, Pakistan.

is a causative organism for scabies that affects an estimated global population of 300 million and remains a disease of significant concern. Recently, a number of potential drug targets were identified for scabies, including hydrolytic enzymes, inactivated paralogues of hydrolytic enzymes, inhibitors of host proteolytic enzymes and other proteins of interest. These discoveries remain confined to academic laboratories and institutions, failing to attract interest from researchers in commercial drug development.

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Determinants Of Eating Habits And Physical Activity Among Female Students Of Government Schools Of Urban City Of Pakistan.

J Ayub Med Coll Abbottabad

January 2021

Health Services Academy, Ministry of National Health Services Regulation and Coordination Islamabad, Pakistan.

Background: Obesity is constantly increasing among adolescents since the last few decades becoming an alarming situation worldwide. The objective of this study was to know the determinants of eating habits and physical activities among school-going female adolescents of public sectors schools of Rawalpindi Pakistan.

Methods: A cross sectional study with mixed method with both quantitative and qualitative approach was conducted on three public sector schools of Rawalpindi Pakistan.

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In the present study, occurrence of arsenic (As) and lead (Pb) is reported in rural and urban household dust (floor and AC filter dust) of the Kingdom of Saudi Arabia (KSA). Several studies have found concerning concentrations of these toxic metals in indoor dust from different countries, but data from this region is missing. The association between studied toxic metals and different socioeconomic parameters was investigated.

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Very recently, two-dimensional (2D) perovskite nanosheets (PNSs), taking the advantages of perovskite as well as the 2D structure properties, have received an enormous level of interest throughout the scientific community. In spite of this incredible success in perovskite nanocrystals (NCs), self-assembly of many nanostructures in metal halide perovskites has not yet been realized, and producing highly efficient red-emitting PNSs remains challenging. In this Letter, we show that by using CsPbBrI perovskite nanoparticles (NPs) as a building block, PNSs can emerge spontaneously under high ambient pressure via template-free self-assembly without additional complicated operation.

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The ongoing escalation of drug-resistant bacteria creates the leading challenges for human health. Current predictions show that deaths due to bacterial illness will be more in comparison to cancer in 2050. Irrational use of antibiotics, prolonged regimen and using as a prophylactic treatment for various infections are leading cause of microbial resistance.

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The shortcomings in Boron neutron capture therapy (BNCT) and Hyperthermia for killing the tumor cell desired for the synthesis of a new kind of material suitable to be first used in BNCT and later on enable the conditions for Hyperthermia to destroy the tumor cell. The desire led to the synthesis of large band gap semiconductor nano-size Boron-10 enriched crystals of hexagonal boron nitride (BNNCs). The contents of BNNCs are analyzed with the help of x-ray photoelectron spectroscopy (XPS) and counter checked with Raman and XRD.

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This paper presents analysis, design and experimentation of a high voltage DC power supply (HVDCPS) with power factor correction based on LLC resonant converter. For power factor correction improvement, the proposed topology has an input rectifier with two filter capacitors, two inductors with a bus capacitor (Cbus) and a resonant tank. To prevent the reverse current flow towards the source diodes (D9 & D10) are employed.

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Genome editing is a relevant, versatile, and preferred tool for crop improvement, as well as for functional genomics. In this review, we summarize the advances in gene-editing techniques, such as zinc-finger nucleases (ZFNs), transcription activator-like (TAL) effector nucleases (TALENs), and clustered regularly interspaced short palindromic repeats (CRISPR) associated with the Cas9 and Cpf1 proteins. These tools support great opportunities for the future development of plant science and rapid remodeling of crops.

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Development of NSAID-loaded nano-composite scaffolds for skin tissue engineering applications.

J Biomed Mater Res B Appl Biomater

November 2020

National Center of Excellence in Molecular Biology (CEMB), University of the Punjab, Lahore, Pakistan.

Scar free healing together with pain management is one of the major considerations in full thickness wound healing. Extensive wounds take longer to heal without any clinical intervention and, hence, need natural or artificial extracellular matrix support for quick skin regeneration. To address these issues, medicated 3D porous biomimetic scaffolds were developed with a unique combination of biopolymers, that is, chitosan, sodium alginate, and elastin, supplemented with a non-steroidal anti-inflammatory drug (NSAID).

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Black mustard () was grown in pots amended with 41 nm ZnO (200-600 mg/kg soil) and 47 nm CuO (12.5-50 mg/kg soil) nanoparticles (NPs) to analyze growth response and yield characteristics. seed germination was not affected by CuO NPs, but significant toxicity was observed by ZnO NP treatment.

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Objective: The objective of this study was to assess the influence of enzyme suppression on the values of various pharmacokinetic factors of orally administered metoclopramide.

Method: This study was conducted in two phases and a 4-week duration was adopted for drug washout. This randomized study involved 12 healthy human volunteers who received a single oral dose of metoclopramide 20 mg.

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Silk fibroin/hydroxyapatite scaffold: a highly compatible material for bone regeneration.

Sci Technol Adv Mater

April 2020

Institute for Advanced Study, Shenzhen University, Nanshan District, Shenzhen, Guangdong, 518060, China.

In recent years remarkable efforts have been made to produce artificial bone through tissue engineering techniques. Silk fibroin (SF) and hydroxyapatite (HA) have been used in bone tissue regeneration as biomaterials due to mechanical properties of SF and biocompatibility of HA. There has been growing interest in developing SF/HA composites to reduce bone defects.

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The geometric, thermodynamic and electronic properties of Pd-graphene nanocomposites are comprehensively studied through quantum mechanical methods. Geometries of these clusters are optimized with the well-calibrated Minnesota functional M06-2X. The adsorption energies calculated at the M06-2X/LANL2DZ level show better agreement with those calculated from MP2/ANO-RCC-VDZP.

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Background: Metoclopramide is metabolized by various cytochrome P450 (CYP) enzymes such as CYP3A4, CYP1A2, CYP2D6, CYP2C9, and CYP2C19. Rifampicin is a non-selective inducer of P-glycoprotein (P-gp) and CYP enzymes such as CYP3A4 and others.

Objective: This study was aimed at the evaluation of rifampicin's enzyme induction effect on the pharmacokinetic parameters of orally administered metoclopramide.

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Waste management is an emerging focus in Pakistan. Specifically, waste-to-energy (WtE) projects are conceived to obtain benefits from municipal waste collection in metropolitan cities. This study provides a brief background of WtE potential, waste collection statistics, type of generated wastes, and current measures to build the confidence of investors in WtE projects.

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The current study was planned to assess how the integration of brief cognitive behaviour therapy (CBT) with hypnotherapy can be productive for a client's quick progress in treatment. It illustrates the effectiveness of two methods of treatment integrated to make better prognosis in the treatment of a depressed Pakistani housewife aged 25 years, who had been suffering for a year. The sessions included hypnotic induction, teaching self-hypnosis with positive suggestions, mood monitoring, use of imagery and relaxation techniques along with specific strategies of brief CBT.

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Combined Pre- and Posttreatment of Paraoxon Exposure.

Molecules

March 2020

Herbert Wertheim College of Medicine, Department of Cellular Biology & Pharmacology, Florida International University, University Park GL 495, 11200 SW 8th St, Miami, FL 33199, USA.

Aims: Organophosphates (OPCs), useful agents as pesticides, also represent a serious health hazard. Standard therapy with atropine and established oxime-type enzyme reactivators is unsatisfactory. Experimental data indicate that superior therapeutic results can be obtained when reversible cholinesterase inhibitors are administered before OPC exposure.

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Progresses on bacterial secretomes enlighten research on Mycoplasma secretome.

Microb Pathog

July 2020

The State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070, China; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, China; Hubei International Scientific and Technological Cooperation Base of Veterinary Epidemiology, Huazhong Agricultural University, Wuhan, 430070, China; International Research Center for Animal Disease (Ministry of Science and Technology of China, Huazhong Agricultural University, Wuhan, 430070, China. Electronic address:

Bacterial secretome is a comprehensive catalog of bacterial proteins that are released or secreted outside the cells. They offer a number of factors that possess several significant roles in virulence as well as cell to cell communication and hence play a core role in bacterial pathogenesis. Sometimes these proteins are bounded with membranes giving them the shape of vesicles called extracellular vesicles (EVs) or outer membrane vesicles (OMVs).

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Identification of 60 secreted proteins for Mycoplasma bovis with secretome assay.

Microb Pathog

June 2020

The State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070, China; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, China; Key Laboratory of Development of Veterinary Diagnostic Products, China Ministry of Agriculture, Hubei International Scientific and Technological Cooperation Base of Veterinary Epidemiology, Huazhong Agricultural University, Wuhan, 430070, China. Electronic address:

Mycoplasma bovis is a risky pathogen mainly responsible for pneumonia and mastitis in cattle. Up to date, its pathogenesis is not clear. Since secreted proteins have a tricky role in M.

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Whey plays an important role in the sports nutrition because of high quality proteins and essential amino acid profile. Nine formulations of sportsman drinks were made using Cheddar, Mozzarella and Paneer whey with normal as well as additional fermentation. The developed sportsman drinks were evaluated for physico-chemical analyses, amino acid profile, viscosity and total plate count along with sensory response during two month storage.

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