Ultrastable CsPbBr@CsPbBr@TiO Composites for Photocatalytic and White Light-Emitting Diodes.

Although cesium halide lead (CsPbX, X = Cl, Br, I) perovskite quantum dots (QDs) have excellent photovoltaic properties, their unstable characteristics are major limitations to application. Previous research has demonstrated that the core-shell structure can significantly improve the stability of CsPbX QDs and form heterojunctions at interfaces, enabling multifunctionalization of perovskite materials. In this article, we propose a convenient method to construct core-shell-structured perovskite materials, in which CsPbBr@CsPbBr core-shell micrometer crystals can be prepared by controlling the ratio of Cs/Pb in the precursor and the reaction time.

Proliferative Diabetic Retinopathy Diagnosis Using Varying-Scales Filter Banks and Double-Layered Thresholding.

Diabetic retinopathy is one of the abnormalities of the retina in which a diabetic patient suffers from severe vision loss due to an affected retina. Proliferative diabetic retinopathy (PDR) is the final and most critical stage of diabetic retinopathy. Abnormal and fragile blood vessels start to grow on the surface of the retina at this stage.

Photophysical and biological aspects of α, β-unsaturated ketones: Experimental and in silico approach.

In this work, four fluorinated α, β-unsaturated ketones named as 3-(3-bromophenyl)-1-(3-(trifluoromethyl)phenyl)prop-2-en-1-one (1), 3-(4-methoxyphenyl)-1-(3-(trifluoromethyl)phenyl) prop-2-en-1-one (2), 3-(3-bromo-5-chloro-2-hydroxyphenyl)-1-(3-(trifluoromethyl)phenyl) prop-2-en-1-one (3) and 3-(2-hydroxy-5-methylphenyl)-1-(3-(trifluoromethyl)phenyl)prop-2-en-1-one (4) were synthesized by Claisen-Schmidt reaction. The synthesized molecules were then characterized through ultraviolet-visible spectroscopy (UV-Vis), Fourier transform infrared (FTIR), H-NMR, C-NMR, and mass spectrometry. The antioxidant potential, Urease inhibition, and interaction of compounds 1-4 with Salmon sperm DNA were experimentally explored and supported by molecular docking studies.

Improved angelization technique against background knowledge attack for 1:M microdata.

With the advent of modern information systems, sharing Electronic Health Records (EHRs) with different organizations for better medical treatment, and analysis is beneficial for both academic as well as for business development. However, an individual's personal privacy is a big concern because of the trust issue across organizations. At the same time, the utility of the shared data that is required for its favorable use is also important.

Preparation of CsPb(Cl/Br)/TiO:Eu composites for white light emitting diodes.

The inherent single narrow emission peak and fast anion exchange process of cesium lead halide perovskite CsPbX (X = Cl, Br, I) nanocrystals severely limited its application in white light-emitting diodes. Previous studies have shown that composite structures can passivate surface defects of NCs and improve the stability of perovskite materials, but complex post-treatment processes commonly lead to dissolution of NCs. In this study, CsPb(Cl/Br) NCs was in-situ grown in TiO hollow shells doped with Eu ions by a modified thermal injection method to prepare CsPb(Cl/Br)/TiO:Eu composites with direct excitation of white light without additional treatment.

In Situ Fabrication of Lead-Free Double Perovskite/Polymer Composite Films for Optoelectronic Devices and Anticounterfeit Printing.

Lead-free double perovskites (DP) have the potential to become a rising star in the next generation of lighting markets by addressing the toxicity and instability issues associated with traditional lead-based perovskites. However, high concentrations of hydrochloric acid (HCl) were often employed as a solvent in the preparation of most DPs, accompanied by slow crystallization at high temperatures, which not only raised the risk and cost in the preparation process, but also had a potential threat to the environment. Here, an in situ fabrication strategy was proposed to realize the crystallization of DP in the polymer at low temperature with a mild dimethyl sulfoxide (DMSO) solvent, and subsequently obtained optically well-behaved CsNaAgBiCl/PMMA composite films (CFs) by doping with Ag, generating bright orange luminescence with a photoluminescence quantum yield (PLQY) of up to 21.

Zinc oxide loaded chitosan-elastin-sodium alginate nanocomposite gel using freeze gelation for enhanced adipose stem cell proliferation and antibacterial properties.

Hydrogels have been the material of choice for regenerative medicine applications due to their biocompatibility that can facilitate cellular attachment and proliferation. The present study aimed at constructing a porous hydrogel composite scaffold (chitosan, sodium alginate and elastin) for the repair of chronic skin wounds. Chitosan-based hydrogel incorporating varying concentrations of zinc oxide nanoparticles i.

Correlates of early initiation of breast feeding and prelacteal feeding: a cross-sectional study in Sindh province of Pakistan.

Objectives: The objective of this study was to determine the prevalence and correlates of early initiation of breast feeding and prelacteal feeding in highly disadvantaged districts in Pakistan.

Design: This cross-sectional study design.

Settings: This study was carried out in twelve districts of the Sindh province of Pakistan.

Computational Investigation of Near-Infrared-Absorbing Indeno[1,2-]indole Analogues as Acceptors in Organic Photovoltaic Devices.

Organic solar cells (OSCs) with fullerene-free acceptors have recently been in high demand in the solar cell market because OSCs are less expensive, more flexible, long-lasting, eco-friendly, and, most importantly, have better photovoltaic performance with a higher PCE. We used INTIC as our reference R molecule and designed five new molecules DF1-DF5 from this R molecule. We attempted to test the power conversion efficiencies of five designed novel molecules, DF1-DF5.

Comparative efficacy of cephradine-loaded silver and gold nanoparticles against resistant human pathogens.

Infections caused by drug-resistant bacteria are major health concerns worldwide. We successfully synthesized cephradine gold nanoparticles (Ceph-Au NPs) and cephradine silver nanoparticles (Ceph-Ag NPs) and compared their efficacy against resistant human pathogens. X-Ray diffraction (XRD), Atomic Force Microscopy (AFM) and Transmission Electron Microscopy (TEM) results showed that average particle size of Ceph-Au NPs and Ceph-Ag NPs were 7 and 12 nm, respectively.

Prediction of Autogenous Shrinkage of Concrete Incorporating Super Absorbent Polymer and Waste Materials through Individual and Ensemble Machine Learning Approaches.

The use of superabsorbent polymers, sometimes known as SAP, is a tremendously efficacious method for reducing the amount of autogenous shrinkage (AS) that occurs in high-performance concrete. This study utilizes support vector regression (SVR) as a standalone machine-learning algorithm (MLA) which is then ensemble with boosting and bagging approaches to reduce the bias and overfitting issues. In addition, these ensemble methods are optimized with twenty sub-models with varying the n estimators to achieve a robust R.

Preparation of ultra-stable and environmentally friendly CsPbBr@ZrO/PS composite films for white light-emitting diodes.

The working stability of perovskite light-emitting diodes (LEDs) has become an urgent bottleneck to be solved in the process of commercialization. Although lead halide perovskite CsPbX (X = Br, I, Cl) quantum dots (QDs) are considered rising stars in the lighting market owing to their excellent optoelectronic properties, they suffer from fluorescence quenching under thermal conditions. Unfortunately, the surfaces of electronic devices inevitably warm up under long-term energization, which is extremely detrimental to the appropriate functioning of CsPbX QDs.

Team diversity, conflict, and trust: Evidence from the health sector.

The current study aims to determine the impact of diversity and intra-team trust on conflict within the health sector of Pakistan. This study also measures the moderating role of trust in the relationship between diversity and conflict among team members. Data was collected using personally administered questionnaires from 61 teams, including 377 respondents working in 4 public sector hospitals in Pakistan, which were selected using a simple random sampling technique.

A strong construction of S-box using Mandelbrot set an image encryption scheme.

The substitution box (S-box) plays a vital role in creating confusion during the encryption process of digital data. The quality of encryption schemes depends upon the S-box. There have been several attempts to enhance the quality of the S-box by using fractal chaotic mechanisms.

Profiling of phthalates, brominated, and organophosphate flame retardants in COVID-19 lockdown house dust; implication on the human health.

In this study, brominated flame retardants (BFRs), phthalates, and organophosphate flame retardants (PFRs) were analyzed in indoor household dust collected during the COVID-19 related strict lockdown (April-July 2020) period. Floor dust samples were collected from 40 households in Jeddah, Saudi Arabia. The levels of most of the analyzed chemicals were visibly high and for certain chemicals multifold high in analyzed samples compared to earlier studies on indoor dust from Jeddah.

Genetic overview of postaxial polydactyly: Updated classification.

Polydactyly or polydactylism, also known as a hyperdactyly, is a congenital limb defect with various morphologic phenotypes. Apart from physical and functional impairments, the presence of polydactyly is an indication of an underlying syndrome in the newborn. Usually, it follows as an autosomal dominant/recessive inheritance pattern with defects in the limb development's anteroposterior patterning.

Fixed Dose Combination Tablets of Aripiprazole and Divalproex Sodium: a Pilot Pharmacokinetic Study in Human Volunteers.

A combination product of aripiprazole (antipsychotic) and divalproex sodium (mood stabilizer) was recently developed to establish their tolerability and safety in fixed dose combination (FDC). A pilot pharmacokinetic (PK) open-labeled parallel study on healthy human volunteers was carried out to assess the PK of FDC of aripiprazole/divalproex sodium in comparison with its individual components with a view to rationalize therapeutic regimen and potentially improve compliance of bipolar patients in future. A total of 24 volunteers were randomized to aripiprazole 5mg, divalproex sodium 500mg, and FDC (aripiprazole/divalproex sodium 5/500 mg) enteric-coated tablets.

Synthesis and Evaluation of Finasteride-Loaded HPMC-Based Nanogels for Transdermal Delivery: A Versatile Nanoscopic Platform.

Herein, we report nanogels comprising diverse feed ratio of polymer hydroxypropyl methylcellulose (HPMC), monomer acrylic acid (AA), and cross-linker methylene bisacrylamide (MBA) fabricated for transdermal delivery of finasteride (FIN). Free radical solution polymerization method with subsequent condensation was employed for the synthesis using ammonium per sulfate (APS) and sodium hydrogen sulfite (SHS) as initiators. Carbopol-940 gel (CG) was formulated as assisting platform to deliver FIN nanogels transdermally.

Barriers and facilitators to pharmacovigilance activities in Pakistan: A healthcare professionals-based survey.

The timely reporting of adverse drug reactions (ADRs) could improve pharmacovigilance (PV) in a healthcare system. However, in almost all healthcare systems barriers exist that lead to the underreporting of ADRs. The objective of this study was to identify the barriers and facilitators regarding PV activities from the point of view of healthcare professionals (HCPs) in Lahore, Pakistan.

Biodegradation of crude oil in seawater by using a consortium of symbiotic bacteria.

This work presents the enhancement of oil biodegradation in seawater using a mixture of oil and microorganisms. Retardation of crude oil biodegradation in seawater is hypothetically due to the inhibiting of metabolites produced by the oil bacterium which inhibit its enzymes. For this purpose, the bacteria consortium consisting of an active oil-oxidizing bacterium (AR3-Pseudomonas pseudoalcaligenes) and two oil-resistant and active heterotrophic bacteria (OG1 and OG2-Erythrobacter citreus) were formed.

Sesquiterpene from Polygonum barbatum disrupts mitochondrial membrane potential to induce apoptosis and inhibits metastasis by downregulating matrix metalloproteinase and osteopontin in NCI-H460 cells.

Globally, lung cancer accounts for 18% of cancer-associated mortalities. Among the subtypes, non-small cell lung cancer (NSCLC) is the most prevalent. The increased resistance and poor survival rates signify disease aggressiveness and thus require a search for an alternative anticancer molecule.

A novel CAPTCHA solver framework using deep skipping Convolutional Neural Networks.

A Completely Automated Public Turing Test to tell Computers and Humans Apart (CAPTCHA) is used in web systems to secure authentication purposes; it may break using Optical Character Recognition (OCR) type methods. CAPTCHA breakers make web systems highly insecure. However, several techniques to break CAPTCHA suggest CAPTCHA designers about their designed CAPTCHA's need improvement to prevent computer vision-based malicious attacks.

Antiurease screening of alkyl chain-linked thiourea derivatives: biological activities, molecular docking, and dynamic simulations studies.

Urease has become an important therapeutic target because it stimulates the pathogenesis of many human health conditions, such as pyelonephritis, the development of urolithiasis, hepatic encephalopathy, peptic ulcers, gastritis and gastric cancer. A series of alkyl chain-linked thiourea derivatives were synthesized to screen for urease inhibition activity. Structure elucidation of these compounds was done by spectral studies, such as IR, H NMR and C NMR, and MS analysis.