153 results match your criteria: "CNRS-Aix Marseille University[Affiliation]"

Face swapping in seizure videos for patient deidentification.

Epilepsy Res

November 2024

Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taiwan; College of Medicine, National Yang Ming Chiao Tung University College of Medicine, Taiwan; Brain Research Center, National Yang Ming Chiao Tung University, Taiwan. Electronic address:

Article Synopsis
  • The study tested various AI face-swapping models on videos of epileptic seizures to maintain patient privacy while preserving important clinical details.
  • Three open-source models were used to replace original faces in seizure videos, with evaluations conducted by both AI metrics and expert clinicians.
  • Results showed that all models were effective at concealing original identities, but the GHOST model was slightly better at preserving clinically relevant details, suggesting potential for enhancing educational resources while protecting patients' identities.
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Letters, Words, Sentences, and Reading.

J Cogn

August 2024

Centre de Recherche en Psychologie et Neurosciences, CNRS & Aix-Marseille University, Marseille, France.

In this personal, and therefore highly selective, review article I summarize work performed in collaboration with numerous colleagues on how skilled adult readers perform identification tasks and speeded binary decision tasks involving single letters and visually presented words and sentences. The overarching aim is to highlight similarities in the processing performed at three key levels involved in written language comprehension (in languages that use an alphabetic script): letters, words, and sentences. The comparisons are made using behavioral data obtained with: i) speeded (response-limited) binary decision tasks; and ii) the effects of simultaneous surrounding context on letter and word identification using both data-limited (non-speeded) and response-limited procedures.

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Vestibular problems are frequent reasons for primary care consultations. However, there is considerable uncertainty about the prevalence and cost of vestibular disorders. Despite ambiguous effectiveness data, the histamine analogue betahistine is widely and almost exclusively used for treatment of vertigo.

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Hydraulic fracturing plays a major role in cavity formation during embryonic development, when pressurized fluid opens microlumens at cell-cell contacts, which evolve to form a single large lumen. However, the fundamental physical mechanisms behind these processes remain masked by the complexity and specificity of biological systems. Here, we show that adhered lipid vesicles subjected to osmotic stress form hydraulic microlumens similar to those in cells.

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Salinity stress is a major threat to crop growth and productivity. Millets are stress-tolerant crops that can withstand the environmental constraints. Foxtail millet is widely recognized as a drought and salinity-tolerant crop owing to its efficient ROS scavenging mechanism.

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Lexical competition in the flankers task revisited.

PLoS One

October 2023

Laboratoire de Psychologie Cognitive, CNRS & Aix-Marseille University, Marseille, France.

We investigated the impact of flanking stimuli that are orthographic neighbors of central target words in the reading version of the flankers task. Experiment 1 provided a replication of the finding that flanking words that are orthographic neighbors of central target words (e.g.

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BDNF as potential biomarker of epilepsy severity and psychiatric comorbidity: pitfalls in the clinical population.

Epilepsy Res

September 2023

APHM, Timone Hospital, Epileptology and Cerebral Rhythmology, Marseille, France; Aix Marseille Univ, INSERM, INS, Inst Neurosci Syst, Marseille, France.

Article Synopsis
  • The study investigated the role of brain-derived neurotrophic factor (BDNF) in epilepsy, specifically looking at its potential as a biomarker for epilepsy severity and related psychiatric conditions.
  • It analyzed serum BDNF levels in epilepsy patients from four centers in France, while documenting various clinical characteristics and conducting psychiatric screenings.
  • The results showed no significant correlation between serum BDNF levels and epilepsy features or depression, but found that the presence of anti-seizure medications (ASM) was linked to increased BDNF, especially with valproate and perampanel.
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Adding automated decision-tree models to multiparametric MRI for parotid tumours improves clinical performance.

Eur J Radiol

September 2023

Department of Radiology, Conception Hospital, Aix-Marseille Univ, Marseille, France; CNRS-Aix-Marseille University, CRMBM (UMR73-39), Marseille, France. Electronic address:

Article Synopsis
  • The study aimed to enhance the diagnosis of parotid gland tumors by developing automated decision-tree models using multiparametric MRI data, comparing their effectiveness to traditional morphological sequences.
  • A total of 206 MRIs were analyzed to build predictive models, which included various MRI parameters, showing a significant improvement in diagnostic performance for most tumor types when multiparametric analysis was used.
  • Key findings indicated that the ADCmean and the mean extracellular-extravascular space coefficient were the most effective parameters for distinguishing between different histological types of tumors, leading to better non-invasive diagnostic outcomes.
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Background: In endurance running, elite Kenyan runners are characterized by longer thigh, shank, and Achilles tendon (AT) lengths combined with shorter fascicles and larger medial gastrocnemius (MG) pennation angles than elite Japanese runners. These muscle-tendon characteristics may contribute to the running performance of Kenyans. Furthermore, these specific lower-leg musculoskeletal architectures have been confirmed not only in elite Kenyan runners but also in non-athletic Kenyans since early childhood.

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Article Synopsis
  • - Salinity negatively impacts plant growth by increasing reactive oxygen species (ROS), which damage vital cellular components; however, some ROS are necessary for plant development and signaling.
  • - The study explored how Zinc (Zn) affects proline metabolism and stress responses in proso millet, revealing that low doses of Zn can counteract the harmful effects of salt stress on plant growth.
  • - Results showed that low levels of Zn improved various growth metrics (e.g., shoot/root length) and proline content, indicating enhanced resilience against salt-induced stress through increased enzyme activity related to proline biosynthesis.
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Foreign speech sound discrimination and associative word learning lead to a fast reconfiguration of resting-state networks.

Neuroimage

May 2023

Department of Computational Linguistics, Computational Neuroscience of Speech & Hearing, University of Zurich, Zurich, Switzerland; Center for Neuroscience Zurich, University and ETH of Zurich, Zurich, Switzerland; Competence center Language & Medicine, University of Zurich, Switzerland.

Learning new words in an unfamiliar language is a complex endeavor that requires the orchestration of multiple perceptual and cognitive functions. Although the neural mechanisms governing word learning are becoming better understood, little is known about the predictive value of resting-state (RS) metrics for foreign word discrimination and word learning attainment. In addition, it is still unknown which of the multistep processes involved in word learning have the potential to rapidly reconfigure RS networks.

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Unorthodox regulation of the MglA Ras-like GTPase controlling polarity in Myxococcus xanthus.

FEBS Lett

March 2023

Laboratoire de Chimie Bactérienne, Institut de Microbiologie de la Méditerranée, CNRS-Aix-Marseille University, France.

Motile cells have developed a large array of molecular machineries to actively change their direction of movement in response to spatial cues from their environment. In this process, small GTPases act as molecular switches and work in tandem with regulators and sensors of their guanine nucleotide status (GAP, GEF, GDI and effectors) to dynamically polarize the cell and regulate its motility. In this review, we focus on Myxococcus xanthus as a model organism to elucidate the function of an atypical small Ras GTPase system in the control of directed cell motility.

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The electrophysiological correlates of word pre-activation during associative word learning.

Int J Psychophysiol

December 2022

Cognition and Brain Plasticity Group, Bellvitge Biomedical Research Institute, L'Hospitalet de Llobregat, 08097 Barcelona, Spain; Department of Cognition, Development and Educational Psychology, Campus Bellvitge, University of Barcelona, L'Hospitalet de Llobregat, 08097 Barcelona, Spain; Institució Catalana de Recerca i Estudis Avançats, ICREA, 08010 Barcelona, Spain. Electronic address:

Human beings continuously make use of learned associations to generate predictions about future occurrences in the environment. Such memory-related predictive processes provide a scaffold for learning in that mental representations of foreseeable events can be adjusted or strengthened based on a specific outcome. Learning the meaning of novel words through picture-word associations constitutes a prime example of associative learning because pictures preceding words can trigger word prediction through the pre-activation of the related mnemonic representations.

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Drought stress is one of the most severe abiotic stresses affecting soil fertility and plant health, and due to climate change, it is destined to increase even further, becoming a serious threat to crop production. An efficient, eco-friendly alternative is the use of plant growth-promoting bacteria (PGPB), which can promote plant fitness through direct and indirect approaches, protecting plants from biotic and abiotic stresses. The present study aims to identify bacterial consortia to promote L.

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Single people are more likely to die from COVID-19. Here we study whether this higher death rate could be partly explained by differences in compliance with protective health measures against COVID-19 between single and married people, and the drivers of this marital compliance gap. Data collected from 46,450 respondents in 67 countries reveal that married people are more likely to comply with protective measures than single people.

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The acute and delayed phases of the functional recovery pattern after running exercise have been studied mainly in men. However, it seems that women are less fatigable and/or recover faster than men, at least when tested in isometric condition. After a 20 km graded running race, the influence of sex on the delayed phase of recovery at 2-4 days was studied using a horizontal ballistic force-velocity test.

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SignificanceNanoporous carbon texture makes fundamental understanding of the electrochemical processes challenging. Based on density functional theory (DFT) results, the proposed atomistic approach takes into account topological and chemical defects of the electrodes and attributes to them a partial charge that depends on the applied voltage. Using a realistic carbon nanotexture, a model is developed to simulate the ionic charge both at the surface and in the subnanometric pores of the electrodes of a supercapacitor.

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Article Synopsis
  • Co-variations in resting state neuronal activity come from multiple sources, including inputs from different brain areas and fluctuations in neuromodulatory systems.
  • The researchers conducted extensive recordings from over a thousand electrodes in the visual cortex of non-human primates, creating a detailed resting state dataset with high resolution.
  • The paper outlines the dataset, explains its data formats and collection methods, and discusses its potential for providing new insights into how background activity affects visual information processing in the brain.
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ProbeInterface: A Unified Framework for Probe Handling in Extracellular Electrophysiology.

Front Neuroinform

February 2022

Department of Biosystems Science and Engineering, ETH Zurich, Zurich, Switzerland.

Recording neuronal activity with penetrating extracellular multi-channel electrode arrays, more commonly known as neural probes, is one of the most widespread approaches to probe neuronal activity. Despite a plethora of available extracellular probe designs, the time-consuming process of mapping of electrode channel order and relative geometries, as required by spike-sorting software is invariably left to the end-user. Consequently, this manual process is prone to mis-mapping mistakes, which in turn lead to undesirable spike-sorting errors and inefficiencies.

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Acoustic emission analysis is promising to investigate the physiological events leading to drought-induced injury and mortality. However, their nature and source are not fully understood, making this technique difficult to use as a direct measure of the loss of xylem hydraulic conductance. Acoustic emissions were recorded during severe dehydration in lavender plants (Lavandula angustifolia) and compared with the dynamics of embolism development and cell damage.

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Models of visual word recognition differ as to how print exposure modulates orthographic precision. In some models, precision is the optimal end state of a lexical representation; the associations between letters and positions are initially approximate and become more precise as readers gain exposure to the word. In others, flexible orthographic coding that allows for rapid access to semantics (i.

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Global organization of neuronal activity only requires unstructured local connectivity.

Elife

January 2022

Institute of Neuroscience and Medicine and Institute for Advanced Simulation and JARA Institut Brain Structure-Function Relationships, Jülich Research Centre, Jülich, Germany.

Article Synopsis
  • Modern electrophysiological techniques can record the activity of many neurons at once, revealing that they often function within low-dimensional patterns despite spatial separation.
  • The research uses both in vivo recordings and theoretical models to analyze coordination patterns in the macaque motor cortex, highlighting that varying local connectivity fosters complex inter-neuronal cooperation.
  • This study connects the brain's structural variations to how coordination among neurons adapts to specific tasks, explaining why similar covariance patterns occur during both resting and active states.
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Orthographic relatedness and transposed-word effects in the grammatical decision task.

Atten Percept Psychophys

April 2022

Laboratoire de Psychologie Cognitive, CNRS & Aix-Marseille University, 3 place Victor Hugo, 13331, Marseille, France.

In two on-line experiments (N = 386) we asked participants to make speeded grammatical decisions to a mixture of syntactically correct sentences and ungrammatical sequences of words. In Experiment 1, the ungrammatical sequences were formed by transposing two inner words in a correct sentence (e.g.

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Natural Products as Potential Antiviral Drugs: The Specific Case of Marine Biotoxins.

Russ J Bioorg Chem

December 2021

Institut de Biologie du Développement de Marseille (IBDM), UMR-7288 CNRS Aix-Marseille University, 13288 Marseille Cedex, France.

To fight against various viral infections researchers turned to new chemical structures resulting from natural medicinal plants and more recently from "marine origin" as sources of active molecules against viral infections. The present manuscript describes complex marine origin drugs, their chemical complex structure, their therapeutic use, and their antiviral properties. Emphasis is placed more particularly on the properties of ionic channels (Na, K, Ca) blockers compounds from marine origin, named , derived from "dinoflagellates microalgae".

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Article Synopsis
  • Anaerobic fungi like Caecomyces churrovis and methanogenic archaea such as Methanobacterium bryantii work together in the rumen to break down lignocellulose, indicating that microbes from different habitats can form beneficial relationships based on their metabolic functions.!* -
  • Research found that co-culturing C. churrovis with M. bryantii led to increased gene expression for enzymes related to carbohydrate breakdown and sugar uptake, suggesting that their partnership enhances biomass decomposition capabilities.!* -
  • The study highlighted the importance of a high-quality genome sequencing of C. churrovis, revealing significant genetic features that relate to carbohydrate processing and confirming that such co-cultures can boost
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